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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Dacoplice 45mg Tablet 30's

Dacoplice 45mg Tablet 30's is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Dacoplice 45mg Tablet 30's is used as a first-line therapy in the treatment of metastatic NSCLC with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations.

Dacoplice 45mg Tablet 30's consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This prevents the abnormal growth of cancer cells and thus reduces the further spread to other parts of the body.

Dacoplice 45mg Tablet 30's may cause certain side effects such as diarrhea, rash, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, hair loss, decreased appetite, decreased weight loss, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dacoplice 45mg Tablet 30's should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Dacoplice 45mg Tablet 30's based on the severity of your condition.

Avoid taking Dacoplice 45mg Tablet 30's if you are allergic to it or any other components of it. Before taking Dacoplice 45mg Tablet 30's, inform your doctor if you have/had liver or kidney disease and lung disease other than lung cancer. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

DACOMITINIB-45MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Dacoplice 45mg Tablet 30's

Non-small cell lung cancer (NSCLC).

Medicinal Benefits

Dacoplice 45mg Tablet 30's contains Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. In this way, Dacoplice 45mg Tablet 30's stops the body's production, spread and growth of cancerous cells.

Side Effects of Dacoplice 45mg Tablet 30's

  • Dry skin
  • Nausea
  • Rash
  • Pruritus (itching)
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching or skin rash
  • Mouth sores
  • Decreased weight loss
  • Nail inflammation
  • Dry, red and itchy eyes
  • Abdominal pain

Directions for Use

Take Dacoplice 45mg Tablet 30's as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

To treat your condition effectually, continue taking Dacoplice 45mg Tablet 30's for the period that your doctor has prescribed. Avoid taking Dacoplice 45mg Tablet 30's if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Effective birth control pills should be used for at least 17 days after the last dose of the medicine. Dacoplice 45mg Tablet 30's may cause severe diarrhea, severe skin conditions, and Interstitial lung disease in some patients. Hence, inform your doctor about your complete medication and medical history before taking Dacoplice 45mg Tablet 30's. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children as the safety and efficacy are not established.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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DacomitinibLansoprazole
Severe
DacomitinibAtomoxetine
Severe

Drug-Drug Interactions

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DacomitinibLansoprazole
Severe
How does the drug interact with Dacoplice 45mg Tablet 30's:
Co-administration of Lansoprazole can make Dacoplice 45mg Tablet 30's less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Lansoprazole with Dacoplice 45mg Tablet 30's can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting to a doctor.
DacomitinibAtomoxetine
Severe
How does the drug interact with Dacoplice 45mg Tablet 30's:
Taking Atomoxetine and Dacoplice 45mg Tablet 30's may significantly increase the blood levels of atomoxetine. This can increase side effects (dizziness, dry mouth, loss of appetite, sleep disturbances, and heart palpitations).

How to manage the interaction:
Although taking Atomoxetine and Dacoplice 45mg Tablet 30's together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, dry mouth, loss of appetite, sleep disturbances, and rapid heartbeats, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DacomitinibEsomeprazole
Severe
How does the drug interact with Dacoplice 45mg Tablet 30's:
Esomeprazole can make Dacoplice 45mg Tablet 30's less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esomeprazole with Dacoplice 45mg Tablet 30's can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
DacomitinibPantoprazole
Severe
How does the drug interact with Dacoplice 45mg Tablet 30's:
Taking Pantoprazole can make Dacoplice 45mg Tablet 30's less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pantoprazole with Dacoplice 45mg Tablet 30's together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • RABEPRAZOLE
  • PANTOPRAZOLE
  • LANSOPRAZOLE
  • CODEINE
  • HALOPERIDOL
  • ARIPIPRAZOLE
  • NORTRIPTYLINE

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Special Advise

  • Avoid being under the sun for a long time, as prolonged duration of sun exposure may cause serious hypersensitivity reactions.
  • Your doctor may suggest blood tests to check for any changes in the patient during the treatment period.

Disease/Condition Glossary

Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an Uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. There are different forms of lung cancer. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.

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