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  3. Dacoplice 45mg Tablet 30's

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

DACOMITINIB-45MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dacoplice 45mg Tablet

Dacoplice 45mg Tablet is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Dacoplice 45mg Tablet is used as a first-line therapy in the treatment of metastatic NSCLC with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations.

Dacoplice 45mg Tablet consists of Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This prevents the abnormal growth of cancer cells and thus reduces the further spread to other parts of the body.

Dacoplice 45mg Tablet may cause certain side effects such as diarrhea, rash, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, hair loss, decreased appetite, decreased weight loss, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Dacoplice 45mg Tablet should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Dacoplice 45mg Tablet based on the severity of your condition.

Avoid taking Dacoplice 45mg Tablet if you are allergic to it or any other components of it. Before taking Dacoplice 45mg Tablet , inform your doctor if you have/had liver or kidney disease and lung disease other than lung cancer. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.

Uses of Dacoplice 45mg Tablet

Non-small cell lung cancer (NSCLC).

Directions for Use

Take Dacoplice 45mg Tablet as prescribed by the doctor. Swallow it as a whole with a glass of water. Do not crush, break, or chew it.

Medicinal Benefits

Dacoplice 45mg Tablet contains Dacominitib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. In this way, Dacoplice 45mg Tablet stops the body's production, spread and growth of cancerous cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dacoplice 45mg Tablet
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.
  • Exercise regularly to maintain a healthy weight.
  • Follow a proper diet; avoid sugary snacks and drinks.
  • Manage stress with yoga or meditation.
  • Limit alcohol consumption.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Prefer liquid food like juices and soups when you are not likely to eat.
  • Avoid spicy, fatty and fried foods as they cause stomach upset.
  • Eat small and frequent meals, avoiding large meals at a time.
  • Add healthy foods in your diet like fruits and vegetables.
  • Take starchy food like cereals, bread and potatoes etc.
  • Dehydration would need immediate medical attention if its severe where medical help can save you from crisis.
  • In case the level of dehydration is from mild to moderate, drink plenty of water for an immediate relief.
  • Seek a place where the surrounding temperature is less and try to stay away from heat and humidity.
  • Lie down by keeping a cool and wet towel on your forehead to prevent high temperature in your body to avoid dehydration.
  • Talk to your medical practitioner and use oral rehydrating salts to replace the lost salts from your body.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Drug Warnings

To treat your condition effectually, continue taking Dacoplice 45mg Tablet for the period that your doctor has prescribed. Avoid taking Dacoplice 45mg Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Effective birth control pills should be used for at least 17 days after the last dose of the medicine. Dacoplice 45mg Tablet may cause severe diarrhea, severe skin conditions, and Interstitial lung disease in some patients. Hence, inform your doctor about your complete medication and medical history before taking Dacoplice 45mg Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children as the safety and efficacy are not established.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dacoplice 45mg Tablet:
Taking Atomoxetine and Dacoplice 45mg Tablet may significantly increase the blood levels of atomoxetine. This can increase side effects (dizziness, dry mouth, loss of appetite, sleep disturbances, and heart palpitations).

How to manage the interaction:
Although taking Atomoxetine and Dacoplice 45mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, dry mouth, loss of appetite, sleep disturbances, and rapid heartbeats, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Dacoplice 45mg Tablet:
Taking Pantoprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Pantoprazole with Dacoplice 45mg Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dacoplice 45mg Tablet:
Esomeprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esomeprazole with Dacoplice 45mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Dacoplice 45mg Tablet:
Co-administration of Lansoprazole can make Dacoplice 45mg Tablet less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Lansoprazole with Dacoplice 45mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dacoplice 45mg Tablet contains Dacominitib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.

The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer, followed by coughing.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • RABEPRAZOLE
  • PANTOPRAZOLE
  • LANSOPRAZOLE
  • CODEINE
  • HALOPERIDOL
  • ARIPIPRAZOLE
  • NORTRIPTYLINE

Special Advise

  • Avoid being under the sun for a long time, as prolonged duration of sun exposure may cause serious hypersensitivity reactions.
  • Your doctor may suggest blood tests to check for any changes in the patient during the treatment period.

Disease/Condition Glossary

Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an Uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. There are different forms of lung cancer. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.

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