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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dajio-M 1000 Tablet

Dajio-M 1000 Tablet belongs to the class of 'antidiabetic drugs', primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Dajio-M 1000 Tablet also lowers the risk of heart failure in type 2 diabetic patients with heart diseases. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. Dajio-M 1000 Tablet is not indicated for use in type 1 diabetes.

Dajio-M 1000 Tablet is composed of two antidiabetic medicines, namely: Metformin and Dapagliflozin. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine.

Take Dajio-M 1000 Tablet as advised by your doctor. Some common side effects of Dajio-M 1000 Tablet include nausea, vomiting, diarrhoea, headache, weakness, runny nose, genital infection, dizziness, taste changes, and sore throat. Sometimes, Dajio-M 1000 Tablet can cause side effects like lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation) and diabetic ketoacidosis (excess production of blood acids (ketones)). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Dajio-M 1000 Tablet may cause hypoglycaemia (low blood sugar); hence it advised to take healthy food with enough calories and avoid heavy exercises. Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Dajio-M 1000 Tablet , let your doctor know if you have any medical history of heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, low blood pressure, and yeast infection of genitals. It is advised to avoid your alcohol intake while using Dajio-M 1000 Tablet to decrease the risk of lactic acidosis. Dajio-M 1000 Tablet is not recommended for use during the second or third trimester of pregnancy and breastfeeding.

Uses of Dajio-M 1000 Tablet

Type 2 Diabetes mellitus.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it. Take it preferably with a meal since it lowers blood sugar levels and may cause gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

Dajio-M 1000 Tablet treats type 2 diabetes mellitus and contains Metformin and Dapagliflozin. Metformin is a biguanide and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. Dajio-M 1000 Tablet also reduces the risk of heart failure in patients with type 2 diabetes and heart disease. Dajio-M 1000 Tablet may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Storage

Keep out of sight and reach of children.
Side effects of Dajio-M 1000 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

Inform your doctor if you take other antidiabetic drugs so that the dosage of Dajio-M 1000 Tablet will be adjusted accordingly. Do not abruptly stop taking Dajio-M 1000 Tablet midway if the doctor did not advise you. Dajio-M 1000 Tablet may cause hypoglycaemia (low blood sugar); hence it is advised to make healthy food with enough calories and avoid heavy exercises. Brief your medical history to doctor if you have any heart, kidney or liver diseases, breathing problems (asthma, obstructive lung diseases), blood problems like anaemia (lack of blood cells), vitamin B12 deficiency, pancreas problems/surgery, dehydration, alcohol use, low blood pressure, and yeast infection of genitals before taking Dajio-M 1000 Tablet . Avoid alcohol intake while using Dajio-M 1000 Tablet since it may increase the risk of lactic acidosis. Dajio-M 1000 Tablet is not recommended for use during the second or third trimester of pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Dajio-M 1000 Tablet is not recommended for people younger than 18 years of age.

Drug-Drug Interactions

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MetforminIopamidol
Critical
MetforminIoglycamic acid
Critical

Drug-Drug Interactions

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MetforminIopamidol
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iopamidol with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Ioglycamic acid with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iohexol with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iopromide with Dajio-M 1000 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with Dajio-M 1000 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIocarmic acid
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Dajio-M 1000 Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iodixanol with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIofendylate
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iofendylate with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Dajio-M 1000 Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iopydol with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Dajio-M 1000 Tablet:
Co-administration of Iopentol with Dajio-M 1000 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Dajio-M 1000 Tablet with Iopentol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Dajio-M 1000 Tablet for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dajio-M 1000 Tablet .
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas. 

Side Effects of Dajio-M 1000 Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Weakness
  • Runny nose
  • Genital infection
  • Dizziness
  • Taste changes
  • Sore throat
  • Lactic acidosis (build-up of lactic acid in the bloodstream) (rare)
  • Diabetic ketoacidosis (a diabetic complication with excess blood acids) (rare)

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dajio-M 1000 Tablet contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

Dajio-M 1000 Tablet may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Dajio-M 1000 Tablet with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.

Your doctor may advise Dajio-M 1000 Tablet with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Dajio-M 1000 Tablet with or without other antidiabetic drugs.

Dajio-M 1000 Tablet should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. Dajio-M 1000 Tablet is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

While using Dajio-M 1000 Tablet , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.

It is not recommended to use Dajio-M 1000 Tablet along with water pills/diuretics. Simultaneous use of Dajio-M 1000 Tablet and water pills causes dehydration and may increase the risk of lactic acidosis.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • HYDROCHLOROTHIAZIDE
  • IBUPROFEN
  • CELECOXIB
  • CIMETIDINE

Special Advise

  • It is advised to monitor your blood sugar levels regularly.
  • If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Dajio-M 1000 Tablet temporarily.
  • Regular monitoring of kidney functioning is advised while using Dajio-M 1000 Tablet .
  • Dajio-M 1000 Tablet may make you test positive for a urine glucose test, hence inform your doctor in advance that you take Dajio-M 1000 Tablet . 

Disease/Condition Glossary

Diabetes mellitus, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots. 

Have a query?

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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

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Pregnancy

Unsafe

Dapagliflozin in Dajio-M 1000 Tablet is not recommended during the second or third trimester of pregnancy. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting Dajio-M 1000 Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Unsafe

Dajio-M 1000 Tablet may be unsafe to use during breastfeeding since it is excreted into the breast milk. Please seek medical advice for further information.

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Driving

Unsafe

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed Dajio-M 1000 Tablet .

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Kidney

Unsafe

Dajio-M 1000 Tablet is contraindicated in patients with severe renal impairment/kidney diseases. Let your doctor know if you have any history of kidney diseases when you are prescribed Dajio-M 1000 Tablet .

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Children

Unsafe

Dajio-M 1000 Tablet is not recommended for people younger than 18 years of age.

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