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  3. Dalpin 5000IU Injection

Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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Composition :

DALTEPARIN-5000IU

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Dalpin 5000IU Injection

Dalpin 5000IU Injection belongs to a class of drugs known as anticoagulants (blood thinner), primarily used to prevent and treat stroke risk, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. A blood clot can occur in any part of the body, leading to a heart attack, stroke and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs and limbs.

Dalpin 5000IU Injection contains ‘Dalteparin’ works by inhibiting the production of clotting factors Xa and thrombin. This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes blood flow easily through your veins, making it less likely to form a serious blood clot. So, an intake of Dalpin 5000IU Injection helps prevent blood clots if you have an increased risk of having a heart attack or stroke.

Take Dalpin 5000IU Injection as prescribed by your doctor. You are advised to take Dalpin 5000IU Injection for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience unusual bleeding, haematoma (blood clotting under the skin), thrombocytopenia (low number of platelets), pain and irritation at the injection site. Most of these side effects of Dalpin 5000IU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dalpin 5000IU Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dalpin 5000IU Injection. Dalpin 5000IU Injection should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. Dalpin 5000IU Injection should be given to children only if prescribed by a doctor. Extra care must be taken while brushing your teeth or shaving to prevent bleeding. If you have a stomach ulcer, kidney or liver problems, high blood pressure or bleeding problems, inform your doctor before taking Dalpin 5000IU Injection. Try not to stop taking this medicine of your own. Stopping a sudden intake of Dalpin 5000IU Injection may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke.

Uses of Dalpin 5000IU Injection

Blood Clot

Directions for Use

Dalpin 5000IU Injection will be administered by a healthcare professional, do not self-administer. If you have kidney or liver problems, please inform your doctor before taking Dalpin 5000IU Injection so that the dose may be adjusted accordingly.

Medicinal Benefits

Dalpin 5000IU Injection belongs to a class of drugs known as anticoagulants or blood thinners. Dalpin 5000IU Injection contains ‘Dalteparin’ used to prevent clot formation in deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain) and heart in patients with atrial fibrillation (irregular heart rhythm). Dalpin 5000IU Injection is primarily used to prevent and treat the risk of the acute coronary syndrome (sudden reduction or blockage of blood flow to the heart) and stroke by reducing blood clot formation. Besides this, it reduces the risk of clots in people who have undergone knee or hip replacement surgeries and abdominal surgery. Dalpin 5000IU Injection works by stopping the action of clotting factor Xa and thrombin (a protein that causes clotting). This prevents fibrinogen's conversion (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation.

Storage

Keep Dalpin 5000IU Injection out of the sight and reach of children.
Side effects of Dalpin 5000IU Injection
  • Increase iron intake through iron-rich foods like red meat, spinach, and beans.
  • Boost vitamin C intake through foods like citrus fruits, bell peppers, and broccoli.
  • Consume foods high in antioxidants, such as berries, leafy greens, and nuts, to help protect against oxidative stress.
  • Stay hydrated by drinking plenty of water.
  • Rest and recover from surgery and transfusion.
  • Avoid strenuous activities like heavy lifting, bending, or exercise.
  • Practice stress-reducing techniques, including meditation, yoga, and deep breathing exercises to help cope with stress and promote relaxation.
  • Follow medical advice and attend follow-up appointments.
  • Focus on consuming a variety of nutrient-dense foods, including plenty of colorful fruits and vegetables, along with whole grains for optimal nutrition.
  • Avoid excessive sugar, salt, and unhealthy fats.
  • Consider increasing foods high in antioxidants, such as berries and leafy greens.
  • Abstain from alcohol or significantly reduce consumption.
  • Achieve and maintain a healthy weight by balancing a nutritious diet with regular physical activity.
  • Engage in moderate exercise, such as brisk walking, most days of the week.
  • Find calm and reduce stress by practicing relaxation methods like mindfulness, meditation, or slow, deliberate breathing.
  • Review medications and supplements with your doctor to ensure they are not contributing to elevated liver enzymes.
  • Reduce saturated fat and sugar intake by limiting processed foods, sugary drinks, and fried foods.
  • Increase fiber intake through plenty of fruits, vegetables, and whole grains.
  • Focus on liver-friendly foods like garlic, turmeric, leafy greens, cruciferous vegetables, and berries.
  • Consider a low-sodium diet by monitoring salt intake.
  • Limit alcohol consumption as even moderate intake can elevate liver enzymes.
  • Engage in regular exercise with moderate-intensity activity most days of the week.
  • Manage weight, as losing a small amount can improve liver health.
  • Quit smoking to prevent worsening liver damage.
  • Practice stress management through relaxation techniques like yoga or meditation.
  • Consult a doctor if your AST and ALT levels are significantly elevated or if you experience symptoms such as fatigue, abdominal pain, jaundice, or loss of appetite.
  • Apply pressure for 5-10 minutes to reduce bleeding.
  • Apply cold compresses or ice packs for 15-20 minutes, repeat every few hours.
  • Consult the doctor and use antihistamines if advised to minimise injection site reaction.
  • Use pain relief medication, like acetaminophen if recommended by the doctor, but avoid NSAIDs if bleeding is a concern.
  • Rotate injection sites and use proper needle size and technique if you are self-administering the medication.
  • Monitor signs such as increased pain, redness, warmth, or pus, and seek medical attention if symptoms worsen.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Staying hydrated helps prevent hematuria by increasing urine production. You should drink about eight glasses of fluid per day, and more in hot weather.
  • Avoiding smoking as it is linked to urinary tract cancers.
  • Eat berries like Cranberries, blueberries, and raspberries can help promote urinary tract health and protect against infection.
  • Taking Vitamin C can help treat urinary tract infections.
  • Avoid irritants that can contribute to hematuria.
  • Empty the bladder regularly, as it can helps in preventing hematuria.

Drug Warnings

  • If you are known to be allergic to Dalpin 5000IU Injection or any other medicines, please tell your doctor.

  • If you are pregnant or breastfeeding, it is advised to consult a doctor before using Dalpin 5000IU Injection.

  • Dalpin 5000IU Injection should be given to children only if prescribed by a doctor.

  • Do not use multiple-dose formulations of Dalpin 5000IU Injection in neonates and infants as they contain benzyl alcohol that may harm a newborn.

  • Dalpin 5000IU Injection should be used with caution in the elderly above 65 years of age as they may be at high risk of bleeding. 

  • If you have diabetes, high blood pressure, congestive heart failure,  blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, had a stroke, kidney, liver or bleeding problems, stomach ulcer, inform your doctor before taking Dalpin 5000IU Injection.

  • Do not stop taking Dalpin 5000IU Injection of your own. Stopping a sudden intake of Dalpin 5000IU Injection may worsen your condition and increase your risk of cardiovascular death, heart attack and stroke. Hence, you should consult a doctor before stopping the dose of Dalpin 5000IU Injection.

  • You should inform the doctor that you are taking Dalpin 5000IU Injection before any surgery is scheduled. 

  • Dalpin 5000IU Injection can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural).

  • Avoid consumption of alcohol while taking Dalpin 5000IU Injection as it may increase the risk of stomach bleeding.

  • Extra care must be taken while brushing your teeth or shaving to prevent bleeding.

Drug-Drug Interactions

verifiedApollotooltip
DalteparinDefibrotide
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Do not make any changes in your diet without first talking to your doctor.
  • Avoid vitamin K-rich foods such as coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, and Brussels sprouts as they may decrease the effectiveness of Dalpin 5000IU Injection.
  • Avoid cranberry juice, grapefruit juice, noni juice, pomegranate juice and green tea as they may interact with Dalpin 5000IU Injection and lead to unwanted side effects.
  • Do the regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid the consumption of alcohol as it may increase the risk of bleeding.
  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dalpin 5000IU Injection.
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart disease.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Dalpin 5000IU Injection contains Dalteparin, an anticoagulant (blood thinner) that inhibits the production of clotting factors Xa (a protein that causes clotting). It prevents the conversion of fibrinogen to fibrin (a protein that binds platelets together and forms a clot) and helps prevent blood clot formation.

No, you are not recommended to take clopidogrel with Dalpin 5000IU Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

It is recommended to avoid taking grapefruit and grapefruit juice while taking Dalpin 5000IU Injection. It contains compounds that slow down the metabolism of Dalpin 5000IU Injection and increase the activity leading to bleeding.

Do not stop taking Dalpin 5000IU Injection without consulting your doctor to worsen the condition. Therefore, take Dalpin 5000IU Injection for as long as your doctor has prescribed it.

Yes, Dalpin 5000IU Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Dalpin 5000IU Injection consists of Dalteparin is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Drug-Drug Interactions Checker List

  • APIXABAN
  • ENOXAPARIN
  • WARFARIN
  • CLOPIDOGREL
  • PRASUGREL
  • RIVAROXABAN
  • DABIGATRAN
  • ANISINDIONE
  • IBUPROFEN
  • NAPROXEN
  • DICLOFENAC
  • BROMFENAC
  • CELECOXIB
  • ABCIXIMAB
  • LISINOPRIL
  • LOSARTAN
  • ALISKIREN
  • SPIRONOLACTONE
  • EPLERENONE

Special Advise

You should have a regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio, to analyze your blood clotting time.

Disease/Condition Glossary

Blood clot: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart or lungs and result in serious conditions.

Deep vein thrombosis (blood clots in legs): Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung): Pulmonary embolism is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough and shortness of breath. Stroke is a condition where a blood clot restricts blood flow to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Heart attack: A heart attack is when a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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