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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

DOXOFYLLINE-400MG

Manufacturer/Marketer :

Constant Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Defill-400 Tablet

Defill-400 Tablet belongs to the class of drugs called 'bronchodilators' primarily used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Defill-400 Tablet contains Doxofylline that acts by inhibiting the phosphodiesterase 4 (PD-4) thereby relaxing the bronchial smooth muscle of lung's airways, making it easier for asthma and COPD patient to breath easily.

Use Defill-400 Tablet as prescribed. Your doctor will recommend you how often you take Defill-400 Tablet based on your medical condition. Some people may experience headache, nausea, vomiting, stomach pain, irritability, insomnia (difficulty in falling or staying asleep) or fast heart rate. Most of these side effects of Defill-400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Defill-400 Tablet is contraindicated in acute myocardial infarction, low blood pressure (hypotension), lactating women and patients allergic to Defill-400 Tablet . Let your doctor know if you are pregnant or planning for pregnancy, before using Defill-400 Tablet . Defill-400 Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance leading to high blood levels even after stopping treatment with Defill-400 Tablet .

Uses of Defill-400 Tablet

Asthma, Chronic obstructive pulmonary disease (COPD)

Directions for Use

Tablet/Capsule: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Syrup: Shake the bottle well before use. Check the label for directions and take it in doses as prescribed by your doctor with the help of a measuring cup.

Medicinal Benefits

Defill-400 Tablet is a bronchodilator and also possess antitussive (cough suppressant) properties that are used to treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD). Defill-400 Tablet works by relaxing muscles and widening the airways of the lungs, especially in asthma and COPD patients. Additionally, Defill-400 Tablet helps in suppressing cough and makes breathing easier by opening airways. Thus it prevents an asthma attack, and an individual can exercise freely if it is taken before exercise or before expected exposure to irritants such as pollen, house dust, cigarette smoke and pets.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defill-400 Tablet

  • Headache
  • Nausea
  • Vomiting
  • Stomach pain
  • Irritability
  • Insomnia (difficulty in falling or staying asleep)
  • Fast heart rate

Drug Warnings

If you are allergic to Defill-400 Tablet or any other medicines, please tell your doctor. You are recommended to avoid taking Defill-400 Tablet with chocolate and caffeinated foods such as cocoa beans or tea leaves as they may increase the risk of severity of side effects. Defill-400 Tablet is contraindicated in breastfeeding mothers. If you are pregnant or planning for pregnancy, please consult a doctor before using Defill-400 Tablet . Do not take Defill-400 Tablet if you have low blood pressure or had a heart attack. Defill-400 Tablet should be used with caution in congestive heart failure patients as these patients have slow drug clearance leading to high blood levels even after stopping treatment with Defill-400 Tablet . If you have low blood pressure, congestive heart failure, hypoxemia (low oxygen levels in the blood), hyperthyroidism (overactive thyroid), pulmonary heart diseases, stomach ulcer, kidney, liver or heart diseases, inform your doctor before taking Defill-400 Tablet .

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.
  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon and lime juice as it may worsen asthma symptoms.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Defill-400 Tablet and irritate the lungs worsening breathing problem.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

Defill-400 Tablet Substitute

Substitutes safety advice
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  • Doxofly 400 mg Tablet 10's

    by AYUR

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  • Duphill Tablet 10's

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Defill-400 Tablet contains Doxofylline which belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Additionally, Defill-400 Tablet possess antitussive (cough suppressant) properties and helps in suppressing cough. Thereby, makes breathing easier by opening airways.

No, you are not recommended to take erythromycin with Defill-400 Tablet as co-administration of these medicines may increase the risk of adverse effects of Defill-400 Tablet . However, please consult a doctor before using other medicines with Defill-400 Tablet .

You are recommended to avoid taking Defill-400 Tablet if you are allergic to Defill-400 Tablet or other xanthine derivatives if you are breastfeeding, suffering from low blood pressure or had a heart attack. However, inform your doctor if you have any of these conditions before taking Defill-400 Tablet .

You are not recommended to take more than the prescribed dose of Defill-400 Tablet as it may cause overdose resulting in irregular heartbeats and fits. However, if you experience any of these symptoms while taking Defill-400 Tablet , please consult a doctor immediately.

No, you are not recommended to smoke while taking Defill-400 Tablet as it may reduce the effectiveness of Defill-400 Tablet .

No, you are not recommended to stop taking Defill-400 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Defill-400 Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Defill-400 Tablet , please consult your doctor.

No, Defill-400 Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Drug-Drug Interactions Checker List

  • ALLOPURINOL
  • CIMETIDINE
  • ERYTHROMYCIN
  • CLINDAMYCIN
  • LINCOMYCIN
  • PROPRANOLOL
  • EPHEDRINE
  • INFLUENZA (LIVE ATTENUATED)
  • PHENYTOIN

Special Advise

  • Regular blood tests are recommended while taking Defill-400 Tablet to monitor potassium levels and levels of Defill-400 Tablet in the blood.
  • Defill-400 Tablet can cause serious side effects, possibly similar, which occurs by taking too much amount of caffeine. So avoid intake of Defill-400 Tablet with caffeinated beverages like chocolate, coffee etc.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times in a week and up to 4 nights in a month whereas, in case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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