Definac P 50/325 Tablet 10's belongs to a class of medications known as a non-steroidal anti-inflammatory drug (NSAID) or pain killer. Definac P 50/325 Tablet 10's is widely useful for treating painful musculoskeletal joint conditions like osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.

Definac P 50/325 Tablet 10's contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

Definac P 50/325 Tablet 10's can be taken with or after the meal. Definac P 50/325 Tablet 10's may cause common side effects like stomach upset, dizziness, light-headedness, malaise, nausea, vomiting, liver dysfunction (hepatitis), pruritis (itchy skin), and rash, although not everybody gets them. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

Definac P 50/325 Tablet 10's is not recommended during the last three months of pregnancy and for children. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects/interactions. Stop taking this medicine if you experience symptoms like tightness of the chest, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Definac P 50/325 Tablet 10's contains Diclofenac (analgesic) and Paracetamol (fever reducer/mild analgesic), effective against painful musculoskeletal pain, joint pain, and skeletal muscle spasms. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX), which causes pain and swelling at the injured or damaged tissue site. On the other hand, paracetamol acts as a mild analgesic (mild pain reducer) and antipyretic (fever reducer), enhancing Diclofenac's pain relief action. It also helps relieve toothache, ear pain, backache and other musculoskeletal-related pain.

• Dizziness
• Light-headedness
• Malaise (feeling of discomfort)
• Nausea
• Vomiting
• Liver dysfunction

Do not take Definac P 50/325 Tablet 10's if you are allergic to any components present in it. Patients with asthma, prolonged bleeding time, wheezing (whistling sound during breath), and blocked airways (bronchospasm) should avoid using Definac P 50/325 Tablet 10's. It is not recommended for use in children less than 14 years of age, people with liver disease, heart disease, or gastric ulcers/bleeding problems. Definac P 50/325 Tablet 10's may be associated with a small increase in the risk of heart attack (myocardial infarction). Pregnant women should not take during their last trimester of pregnancy. Definac P 50/325 Tablet 10's is excreted in the breast milk, so the nursing mother should contact the doctor before its usage. Avoid the consumption of alcohol as it may damage your liver and cause even more side effects on taking this drug. Consult your doctor if your pain, inflammation, and fever symptoms do not disappear even after ten days.

Drug-Drug Interactions: Definac P 50/325 Tablet 10's is shown to interact with various drugs. Some of them include painkillers (naproxen, aspirin, ibuprofen, tramadol, hydrocodone, oxycodone), antibiotics (ciprofloxacin, levofloxacin, moxifloxacin, nalidixic acid, norfloxacin or ofloxacin), diuretics (furosemide and bumetanide), medicines for heart problems or medication for high blood pressure (digoxin), medicines used to lower cholesterol (colestipol and cholestyramine), drugs to treat seizures (phenytoin), medicines that reduce the activity of your immune system (ciclosporin or tacrolimus), steroid medicines (hydrocortisone or prednisolone), blood thinner (warfarin), anti-depressant (duloxetine) and acidity lowering drugs (cimetidine). These drugs may affect the working of Definac P 50/325 Tablet 10's and may alter its efficacy.

Drug-Food Interactions: Excessive caffeine-containing food or drinks like coffee, tea, chocolate and some fizzy drinks should be avoided while taking Definac P 50/325 Tablet 10's. Taking them together may lead to drowsiness and dizziness, and sleepiness.

Drug-Disease Interactions: Definac P 50/325 Tablet 10's interacts with disease conditions, including asthma, urticaria or acute rhinitis, as the attacks precipitate with NSAIDs.

• ASPIRIN
• IBUPROFEN
• NAPROXEN
• CIPROFLOXACIN
• FUROSEMIDE
• TRAMADOL
• HYDROCODONE
• OXYCODONE
• LEVOFLOXACIN
• MOXIFLOXACIN
• NALIDIXIC ACID
• NORFLOXACIN
• OFLOXACIN
• BUMETANIDE
• DIGOXIN
• COLESTIPOL
• CHOLESTYRAMINE
• PHENYTOIN
• CICLOSPORIN
• TACROLIMUS
• HYDROCORTISONE
• PREDNISOLONE
• WARFARIN
• DULOXETINE
• CIMETIDINE

• Physical activity helps strengthen muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
• Performing yoga may also help in improving joint flexibility and pain management.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
• Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Acupuncture, massage and physical therapy may also be helpful.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.

Musculoskeletal pain: It is generally caused by disorders of bones, joints, muscles, tendons, ligaments, or a combination. Injuries (mostly sports-related) are the most common cause of musculoskeletal pain. Muscle pain (myalgia) can be caused due to injury, infection, loss of blood flow to the muscle, infection, or a tumour. Extreme tissue pain and inflammation caused due to sprains, strains, trauma, or post-surgery may require prolonged healing time.

Osteoarthritis: Osteoarthritis is the most common form of joint disorder, which occurs when the protective cartilage that cushions the ends of your bones wears down over time. It can damage any joint, affecting your hands, knees, hips and spine joints.

Ankylosing spondylitis: Ankylosing spondylitis is the painful condition in which fused bones of your spinal cord or vertebrae gets inflamed, leading to hunched spine. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.