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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

Online payment accepted

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Composition :

DEFERASIROX-360MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Defrijet FCT 360 Tablet

Defrijet FCT 360 Tablet belongs to the group of medicines called iron chelators. Defrijet FCT 360 Tablet is indicated for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

The active ingredient in Defrijet FCT 360 Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.

Defrijet FCT 360 Tablet is available in the form of oral formulations. Please take Defrijet FCT 360 Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Defrijet FCT 360 Tablet for as long as your doctor has prescribed it. Do not use Defrijet FCT 360 Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Defrijet FCT 360 Tablet if you are pregnant or breastfeeding. Do not use Defrijet FCT 360 Tablet in more than prescribed doses or longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Defrijet FCT 360 Tablet to rule out any side effects.

Uses of Defrijet FCT 360 Tablet

Defrijet FCT 360 Tablet is indicated for treating chronic iron overload that occurs due to blood transfusions (transfusional hemosiderosis) in patients two years of age and older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Deferasirox is the active component in Defrijet FCT 360 Tablet . It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

Storage

Keep out of sight and reach of children.
Side effects of Defrijet FCT 360 Tablet
  • Your doctor may recommend medications to dissolve the small gallstones (like ursodiol) or use shock waves to break up the stones.
  • Try to eat regular meals because skipping meals can increase the risk of gallstones by making your gallbladder work less efficiently.
  • Eat breakfast soon after you wake up, as cholesterol in bile is highest in the morning.
  • If you are overweight, losing weight gradually can help lower the chance of developing gallstones.
  • Include plenty of fresh vegetables and fruits in your diet.
  • Base your meals around starchy foods like bread, pasta, rice, and potatoes, especially whole grain or high-fibre varieties.

Drug Warnings

Do not take Defrijet FCT 360 Tablet if you are allergic to Defrijet FCT 360 Tablet or its ingredients. Defrijet FCT 360 Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Defrijet FCT 360 Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Defrijet FCT 360 Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Defrijet FCT 360 Tablet:
Using Defrijet FCT 360 Tablet together with ticlopidine may increase the risk of gastrointestinal ulcers and bleeding.

How to manage the interaction:
Co-administration of Ticlopidine with Defrijet FCT 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Defrijet FCT 360 Tablet:
Taking Defrijet FCT 360 Tablet may cause kidney problems and combining it with gentamicin may increase that risk.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Defrijet FCT 360 Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Dehydration can also harm the kidney, therefore drink plenty of fluids if you develop diarrhoea or vomiting during treatment with these medications.
How does the drug interact with Defrijet FCT 360 Tablet:
Taking Defrijet FCT 360 Tablet with methotrexate may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Defrijet FCT 360 Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Defrijet FCT 360 Tablet:
Combining Dipyridamole with Defrijet FCT 360 Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Dipyridamole with Defrijet FCT 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Defrijet FCT 360 Tablet:
Taking Celecoxib with Defrijet FCT 360 Tablet can increase the risk of gastrointestinal bleeding and ulcers.

How to manage the interaction:
Taking Defrijet FCT 360 Tablet with Celecoxib together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience symptoms such as stomach ulcers, bleeding, joint pain, chronic pain, severe stomach pain, feeling bloated, feeling dizzy or lightheaded, feeling sick to your stomach or throwing up, not feeling hungry, or having black or dark stools, feeling weak or confused, irregular heartbeat, diarrhea and feeling dehydrate up. Do not discontinue any medications without consulting a doctor.
DeferasiroxBacitracin
Severe
How does the drug interact with Defrijet FCT 360 Tablet:
Defrijet FCT 360 Tablet may cause kidney problems and combining it with bacitracin may increase that risk.

How to manage the interaction:
Although taking Bacitracin and Defrijet FCT 360 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Defrijet FCT 360 Tablet:
Taking Etodolac with Defrijet FCT 360 Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Taking Defrijet FCT 360 Tablet with Etodolac together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Defrijet FCT 360 Tablet:
Using Defrijet FCT 360 Tablet together with Tirofiban may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Tirofiban with Defrijet FCT 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Defrijet FCT 360 Tablet:
Using Defrijet FCT 360 Tablet together with Prasugrel may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Prasugrel with Defrijet FCT 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
DeferasiroxDanaparoid
Severe
How does the drug interact with Defrijet FCT 360 Tablet:
Combining Danaparoid with Defrijet FCT 360 Tablet can increase the risk of gastrointestinal bleeding.

How to manage the interaction:
Co-administration of Danaparoid with Defrijet FCT 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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DEFERASIROX-360MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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DEFERASIROX-360MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Defrijet FCT 360 Tablet. Avoid consumption of caffeinated drinks during the treatment with Defrijet FCT 360 Tablet. If you experience any unusual symptoms call a doctor.

Diet & Lifestyle Advise

  • Choose foods high in nutrients, such as fruits, vegetables, and whole grains.
  • Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.
  • Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
  • Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol and caffeine consumption.

Habit Forming

No

Therapeutic Class

CHELATING AGENTS

Defrijet FCT 360 Tablet Substitute

Substitutes safety advice

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Deferasirox is the active component in Defrijet FCT 360 Tablet . It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.

No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Defrijet FCT 360 Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.

Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It can cause severe damage to your body, including to your heart, liver and pancreas.

Drug-Drug Interactions Checker List

  • ALUMINIUM HYDROXIDE
  • REPAGLINIDE
  • THEOPHYLLINE
  • BUSULFAN
  • ASPIRIN
  • CELECOXIB
  • DILTIAZEM
  • PARACETAMOL

Special Advise

  • Monitor blood counts, liver function, and renal function monthly.
  • Monitor serum ferritin monthly to assess the patient’s response to therapy and minimize the risk of over-chelation.

Disease/Condition Glossary

Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It can cause severe damage to your body, including to your heart, liver and pancreas.

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