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Written By aquibnaseer ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

DEFLAZACORT-1MG

Manufacturer/Marketer

Wallace Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Defza 1 mg Tablet 6's

Defza 1 mg Tablet 6's belongs to the class of medication called steroid primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.

Defza 1 mg Tablet 6's is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug Defza 1 mg Tablet 6's binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defza 1 mg Tablet 6's class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defza 1 mg Tablet 6's make organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defza 1 mg Tablet 6's is available in both oral tablet and suspension dosage forms. The tablet form of Defza 1 mg Tablet 6's can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defza 1 mg Tablet 6's can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defza 1 mg Tablet 6's based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defza 1 mg Tablet 6's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defza 1 mg Tablet 6's, please inform your doctor that you are allergic (hypersensitive) to Defza 1 mg Tablet 6's. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Defza 1 mg Tablet 6's is not safe to use during pregnancy. 

Uses of Defza 1 mg Tablet 6's

Duchenne muscular dystrophy (DMD) 

Directions for Use

Tablet: Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.Suspension: Measure the suspension in the measuring cup provided with the pack and consume it in the doses as directed by your doctor.

Medicinal Benefits

Defza 1 mg Tablet 6's is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defza 1 mg Tablet 6's is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Defza 1 mg Tablet 6's

Most of the side effects of Defza 1 mg Tablet 6's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defza 1 mg Tablet 6's.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defza 1 mg Tablet 6's. Before taking Defza 1 mg Tablet 6's for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortNevirapine
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Defza 1 mg Tablet:
Co-administration of Defza 1 mg Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortNevirapine
Severe
How does the drug interact with Defza 1 mg Tablet:
Taking Nevirapine with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Nevirapine and Defza 1 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortModafinil
Severe
How does the drug interact with Defza 1 mg Tablet:
Taking Modafinil with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Defza 1 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortVerapamil
Severe
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Verapamil with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Verapamil with Defza 1 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like swelling, weight gain, electrolyte abnormalities, high blood pressure, high blood glucose, muscle weakness, depression, mood swings, acne, thinning skin, stretch marks, easy bruising, bone density loss, cataracts, glaucoma, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist. contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortFosphenytoin
Severe
How does the drug interact with Defza 1 mg Tablet:
Taking Fosphenytoin with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Fosphenytoin and Defza 1 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortDabrafenib
Severe
How does the drug interact with Defza 1 mg Tablet:
Co- administration of Dabrafenib with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dabrafenib and Defza 1 mg Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortTofacitinib
Severe
How does the drug interact with Defza 1 mg Tablet:
Co-administration of Defza 1 mg Tablet with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Defza 1 mg Tablet and Tofacitinib, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortEfavirenz
Severe
How does the drug interact with Defza 1 mg Tablet:
Taking Efavirenz with Defza 1 mg Tablet may significantly reduce the blood levels of Defza 1 mg Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Efavirenz and Defza 1 mg Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortGatifloxacin
Severe
How does the drug interact with Defza 1 mg Tablet:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defza 1 mg Tablet.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Defza 1 mg Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortNelfinavir
Severe
How does the drug interact with Defza 1 mg Tablet:
Coadministration of Nelfinavir with Defza 1 mg Tablet can increase the levels of Defza 1 mg Tablet in the body.

How to manage the interaction:
Taking Nelfinavir with Defza 1 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Defza 1 mg Tablet therapy may elevate Defza 1 mg Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Defza 1 mg Tablet 6's Substitute

Substitutes safety advice
  • Defcort 1 Tablet 6's

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    4.50per tablet
  • Dezacor 1 mg Tablet 10's

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    2.75per tablet
  • Defnalone 1 mg Tablet 10's

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    1.50per tablet
  • Deflaz 1 mg Tablet 6's

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    9.67per tablet
  • Dfz 1 mg Tablet 10's

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    26.55per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • RIFABUTIN
  • CARBAMAZEPINE
  • PHENOBARBITONE
  • PHENYTOIN
  • PRIMIDONE

Special Advise

  • While taking Defza 1 mg Tablet 6's and for at least 4-6 weeks before you start taking it. If you are taking Defza 1 mg Tablet 6's, so do not receive a 'live' vaccine or you could develop a serious infection.  
  • Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Defza 1 mg Tablet 6's.
  • Regular eye check-ups, bone mineral test and liver function test is suggested while using Defza 1 mg Tablet 6's. 

Disease/Condition Glossary

Autoimmune disease: These are a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that starts attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day to day life and promote diseases like arthritis, muscular weakness. The immune system can also damage the organ, which has been transplanted to the patient from another person due to having different blood groups/antigens of donor patients organ. The immune system considers it a foreign harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart. 

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