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Written By aquibnaseer ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Defza 6 Tablet 10's

Defza 6 Tablet 10's belongs to the class of medication called steroid primarily used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally & is unable to distinguish between a foreign cell & a native cell. This condition results in an immune system that starts to attack native cells & organs, leading to medical problems like Duchenne muscular dystrophy, psoriasis & arthritis, etc.

Defza 6 Tablet 10's is an immunosuppressive drug that works by binding to immune system cells and turns off the switches (receptors) that lead to their abnormal functioning or damaging effects. After taking the drug Defza 6 Tablet 10's binds to immune cells, resulting in the inhibition of inflammation & autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. Thus, a Defza 6 Tablet 10's class of drugs is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis & skin psoriasis. Defza 6 Tablet 10's make organ transplantation possible & treats muscle disorders like Duchenne muscular dystrophy.

Defza 6 Tablet 10's is available in both oral tablet and suspension dosage forms. The tablet form of Defza 6 Tablet 10's can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Defza 6 Tablet 10's can be taken as advised by your doctor with a measuring cup. Your doctor will recommend how often you take Defza 6 Tablet 10's based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremor, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Defza 6 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, a disturbed stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may be caused by stopping the medication suddenly.

Before starting Defza 6 Tablet 10's, please inform your doctor that you are allergic (hypersensitive) to Defza 6 Tablet 10's. Extra care is to be taken when a patient has an already existing infection being treated (systemic infection) or has recently had some live virus vaccines. Doctors' consultation is required as Defza 6 Tablet 10's is not safe to use during pregnancy. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

DEFLAZACORT-6MG

Manufacturer/Marketer

Wallace Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Defza 6 Tablet 10's

Duchenne muscular dystrophy (DMD) 

Medicinal Benefits

Defza 6 Tablet 10's is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Defza 6 Tablet 10's is a steroid that interacts with overactive immune cells and slows their activity and decreases the damaging effects they cause in the body. 

Side Effects of Defza 6 Tablet 10's

Most of the side effects of Defza 6 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

Directions for Use

Tablet: Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.Suspension: Measure the suspension in the measuring cup provided with the pack and consume it in the doses as directed by your doctor.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney & liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Defza 6 Tablet 10's.  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Defza 6 Tablet 10's. Before taking Defza 6 Tablet 10's for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortCiprofloxacin
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Defza 6 Tablet 10's:
Co-administration of Defza 6 Tablet 10's and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortCiprofloxacin
Severe
How does the drug interact with Defza 6 Tablet 10's:
Co-administration of Defza 6 Tablet 10's with Ciprofloxacin leads to tendinitis and tendon rupture.

How to manage the interaction:
Although there is an interaction, Ciprofloxacin can be taken with Defza 6 Tablet 10's if prescribed by the doctor. However, if you experience pain or swelling consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from the doctor. Do not stop using any medications without talking to a doctor.
DeflazacortModafinil
Severe
How does the drug interact with Defza 6 Tablet 10's:
Taking Modafinil with Defza 6 Tablet 10's may significantly reduce the blood levels of Defza 6 Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Defza 6 Tablet 10's together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortBempedoic acid
Severe
How does the drug interact with Defza 6 Tablet 10's:
Co-administration of Bempedoic acid and Defza 6 Tablet 10's can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Defza 6 Tablet 10's if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
DeflazacortDiltiazem
Severe
How does the drug interact with Defza 6 Tablet 10's:
Coadministration of Diltiazem with Defza 6 Tablet 10's can increase the levels of Defza 6 Tablet 10's in the body. This increases the risk of side effects.

How to manage the interaction:
Taking Diltiazem with Defza 6 Tablet 10's together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortMifepristone
Severe
How does the drug interact with Defza 6 Tablet 10's:
Taking Mifepristone with Defza 6 Tablet 10's may significantly reduce the blood levels of Defza 6 Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Mifepristone and Defza 6 Tablet 10's together can possibly result in an interaction, they can be taken together if advised by a doctor. However, consult a doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortNafcillin
Severe
How does the drug interact with Defza 6 Tablet 10's:
Taking Nafcillin with Defza 6 Tablet 10's may significantly reduce the blood levels of Defza 6 Tablet 10's, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Nafcillin and Defza 6 Tablet 10's together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortNorfloxacin
Severe
How does the drug interact with Defza 6 Tablet 10's:
Norfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Defza 6 Tablet 10's.

How to manage the interaction:
Although there is an interaction, Norfloxacin can be taken with Defza 6 Tablet 10's if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without talking to a doctor.
DeflazacortTofacitinib
Severe
How does the drug interact with Defza 6 Tablet 10's:
Co-administration of Defza 6 Tablet 10's with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Defza 6 Tablet 10's and Tofacitinib, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortFluconazole
Severe
How does the drug interact with Defza 6 Tablet 10's:
Co-administration of Fluconazole with Defza 6 Tablet 10's can increase the levels of Defza 6 Tablet 10's in the body.

How to manage the interaction:
Taking Fluconazole with Defza 6 Tablet 10's together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, or sudden dizziness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Defza 6 Tablet 10's therapy may elevate Defza 6 Tablet 10's levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • RIFABUTIN
  • CARBAMAZEPINE
  • PHENOBARBITONE
  • PHENYTOIN
  • PRIMIDONE

Diet & Lifestyle Advise

A patient needs to take extra care of hygiene & stay away from places/people believed to be a cause of infection as this drug affects a patient's immune system & thus proper care is to be taken.

 

Habit Forming

No

Special Advise

  • While taking Defza 6 Tablet 10's and for at least 4-6 weeks before you start taking it. If you are taking Defza 6 Tablet 10's, so do not receive a 'live' vaccine or you could develop a serious infection.  
  • Do not eat grapefruit or drink grapefruit juice while taking this medication as grapefruit has interaction with Defza 6 Tablet 10's.
  • Regular eye check-ups, bone mineral test and liver function test is suggested while using Defza 6 Tablet 10's. 

Author Details

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Disease/Condition Glossary

Autoimmune disease: These are a group of disorders in which the immune system doesn't work properly due to various genetic & environmental reasons that starts attacking normal cells, producing various chemicals resulting in unwanted and hazardous effects in patients. The overactive immune system leads to various symptoms that affect day to day life and promote diseases like arthritis, muscular weakness. The immune system can also damage the organ, which has been transplanted to the patient from another person due to having different blood groups/antigens of donor patients organ. The immune system considers it a foreign harmful body, leading to complications after transplanting an organ like a kidney, liver, or heart. 

Defza 6 Tablet 10's Substitute

Substitutes safety advice
  • Defcort 6 Tablet 10's

    13.50per tablet
  • Vellcort 6 mg Tablet 10's

    by AYUR

    14.40per tablet
  • Enzocort 6 Tablet 10's

    18.54per tablet
  • Emflav 6 Tablet 10's

    15.21per tablet
  • Orthocort 6 Tablet 10's

    by AYUR

    13.50per tablet
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