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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

FLUOXETINE-10MG

Manufacturer/Marketer

Tas Med India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Depnil 10 mg Tablet

Depnil 10 mg Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. Depression is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Depnil 10 mg Tablet contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
 
Take Depnil 10 mg Tablet as prescribed. You are advised to take Depnil 10 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Depnil 10 mg Tablet on your own as it could lead to withdrawal symptoms. Do not take Depnil 10 mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Depnil 10 mg Tablet may cause dizziness and might impair your reactions. Depnil 10 mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Depnil 10 mg Tablet as it could lead to increased dizziness.  Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Depnil 10 mg Tablet

Depression, Obsessive-Compulsive Disorder (OCD), Bulimia nervosa (eating disorder) 

Directions for Use

Take Depnil 10 mg Tablet with or without food. Your doctor will decide for how long you need to take Depnil 10 mg Tablet based on your medical condition and response to treatment. Take Depnil 10 mg Tablet exactly as prescribed by the doctor. Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Depnil 10 mg Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Depnil 10 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder with or without agoraphobia. Depnil 10 mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression. Depnil 10 mg Tablet may also be used to treat premenstrual dysphoric disorder (a severe form of premenstrual syndrome). Depnil 10 mg Tablet has fewer unwanted effects than other antidepressant drugs. Depnil 10 mg Tablet is used in combination with other drugs to treat bipolar disorder and treatment-resistant depression.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Depnil 10 mg Tablet

  • Insomnia (difficulty sleeping)
  • Headache
  • Diarrhoea
  • Nausea
  • Fatigue
  • Dry mouth
  • Loss of appetite
  • Indigestion

Drug Warnings

Do not take Depnil 10 mg Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MOA) or have taken them in the last 14days, or if you are taking metoprolol (used to treat high blood pressure). Do not take Depnil 10 mg Tablet along with opioid antagonists such as buprenorphine and naloxone as it might lead to a serious condition called serotonin syndrome. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).  Do not take Depnil 10 mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Depnil 10 mg Tablet may cause dizziness and might impair your reactions. Depnil 10 mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Depnil 10 mg Tablet as it could lead to increased dizziness. 

Drug-Drug Interactions

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FluoxetineCisapride
Severe
FluoxetineGatifloxacin
Severe

Drug-Drug Interactions

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FluoxetineCisapride
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet with Cisapride may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Depnil 10 mg Tablet can be taken with Cisapride if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluoxetineGatifloxacin
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet with gatifloxacin may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, Depnil 10 mg Tablet can be taken with gatifloxacin if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue the medications without consulting a doctor.
FluoxetineParoxetine
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet together with paroxetine may increase the risk of Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Although there is a possible interaction, Depnil 10 mg Tablet can be taken with paroxetine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea (or) side effects such as cognitive and motor impairment, insomnia, drowsiness, seizures, abnormal bleeding, sexual dysfunction.
FluoxetineLinezolid
Severe
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Linezolid with Depnil 10 mg Tablet can result in effects and also Serotonin syndrome (a condition wherein serotonin levels are increased in the body).

How to manage the interaction:
Co-administration of linezolid along with Depnil 10 mg Tablet can possibly lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
FluoxetineArsenic trioxide
Severe
How does the drug interact with Depnil 10 mg Tablet:
Combining Depnil 10 mg Tablet with Arsenic trioxide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Arsenic trioxide with Depnil 10 mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any fainting or irregular heartbeat, it's best to go to the hospital for check-ups. If you experience symptoms like fainting, irregular heartbeat, dizziness, or shortness of breath, make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
FluoxetineChloroquine
Severe
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Chloroquine with Depnil 10 mg Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Depnil 10 mg Tablet together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluoxetineMifepristone
Severe
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Depnil 10 mg Tablet with mifepristone can increase the risk of irregular heart rhythm. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Depnil 10 mg Tablet with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
FluoxetineTetrabenazine
Severe
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Depnil 10 mg Tablet with Tetrabenazine may increase the blood levels and side effects of tetrabenazine.

How to manage the interaction:
Although there is a possible interaction, Depnil 10 mg Tablet can be taken with tetrabenazine if prescribed by the doctor. Consult the doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, fever, heat intolerance, excessive sweating, stiff muscles, and difficulty moving or swallowing. Do not stop using any medications without consulting a doctor.
FluoxetineDofetilide
Severe
How does the drug interact with Depnil 10 mg Tablet:
Combining Depnil 10 mg Tablet with Dofetilide can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Depnil 10 mg Tablet with Dofetilide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or palpitations. Do not stop using any medications without talking to a doctor.
FluoxetineDesvenlafaxine
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet with desvenlafaxine might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is a possible interaction, Depnil 10 mg Tablet can be taken with desvenlafaxine if prescribed by the doctor. Consult the doctor if you experience symptoms of serotonin syndrome such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Depnil 10 mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Depnil 10 mg Tablet may cause weight loss due to loss of appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight. Please consult your doctor if you experience fluctuations in weight while taking Depnil 10 mg Tablet .

Do not discontinue Depnil 10 mg Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually continue taking Depnil 10 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Depnil 10 mg Tablet ; the doctor may reduce the dose gradually.

Depnil 10 mg Tablet may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Depnil 10 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Please consult your doctor before taking Depnil 10 mg Tablet if you have glaucoma as it might cause increased pressure in the eye.

Consult tour doctor before taking Depnil 10 mg Tablet if you are diabetic as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Depnil 10 mg Tablet . Talk to your doctor if you experience fluctuations in blood sugar levels.

Depnil 10 mg Tablet might increase the risk of bone fractures. Talk to your doctor before taking Depnil 10 mg Tablet if you have osteoporosis. Consult your doctor if you experience bone pain.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • NEBIVOLOL
  • BUPRENORPHINE
  • NALOXONE
  • LINEZOLID
  • PIMOZIDE
  • THIORIDAZINE
  • LITHIUM
  • RISPERIDONE
  • METHYLENE BLUE
  • BUPROPION
  • PROPAFENONE
  • FLECAINIDE
  • ATOMOXETINE
  • DESMOPRESSIN
  • MEFLOQUINE
  • CHLOROQUINE
  • MEQUITAZINE
  • CYPROHEPTADINE
  • OXCARBAZEPINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • SELEGILINE
  • TRAMADOL
  • IBUPROFEN
  • ASPIRIN
  • SUMATRIPTAN
  • WARFARIN
  • TAMOXIFEN

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, changes in appetite, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression. 

Obsessive-Compulsive Disorder (OCD): It is a mental disorder which is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions). 

Bulimia nervosa: It is a serious eating disorder which is characterised by binge eating followed by methods to avoid overweight such as vomiting, severe exercise or fasting.

Panic disorder: It is a type of anxiety disorder which causes panic attacks. In this condition, a person experiences a sudden feeling of fear, when, in reality, there is no danger. Symptoms include fast heartbeat, breathing difficulty, chest or stomach pain, weakness or dizziness, and sweating.

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