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  1. Home
  2. Medicine

  3. Depnil 10 mg Tablet 10's

Depnil 10 mg Tablet 10's, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

FLUOXETINE-10MG

Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Depnil 10 mg Tablet

Depnil 10 mg Tablet belongs to a group of medicines called antidepressants used to treat a major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder. Depression is a mood disorder characterised by the feeling of sadness, unhappiness, anger, hopelessness or loss that interferes with a person’s daily activities.
 
Depnil 10 mg Tablet contains ‘Fluoxetine’ which is a selective serotonin reuptake inhibitor. It works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.
 
Take Depnil 10 mg Tablet as prescribed. You are advised to take Depnil 10 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as insomnia (difficulty sleeping), headache, diarrhoea, nausea, fatigue, dry mouth, loss of appetite, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Depnil 10 mg Tablet on your own as it could lead to withdrawal symptoms. Do not take Depnil 10 mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Depnil 10 mg Tablet may cause dizziness and might impair your reactions. Depnil 10 mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Depnil 10 mg Tablet as it could lead to increased dizziness.  Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Depnil 10 mg Tablet

Depression, Obsessive-Compulsive Disorder (OCD), Bulimia nervosa (eating disorder) 

Directions for Use

Take Depnil 10 mg Tablet with or without food. Your doctor will decide for how long you need to take Depnil 10 mg Tablet based on your medical condition and response to treatment. Take Depnil 10 mg Tablet exactly as prescribed by the doctor. Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Depnil 10 mg Tablet belongs to a group of antidepressant medicines called selective serotonin reuptake inhibitors. Depnil 10 mg Tablet is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa (eating disorder), and panic disorder with or without agoraphobia. Depnil 10 mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression. Depnil 10 mg Tablet may also be used to treat premenstrual dysphoric disorder (a severe form of premenstrual syndrome). Depnil 10 mg Tablet has fewer unwanted effects than other antidepressant drugs. Depnil 10 mg Tablet is used in combination with other drugs to treat bipolar disorder and treatment-resistant depression.

Storage

Store in a cool and dry place away from sunlight
Side effects of Depnil 10 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug Warnings

Do not take Depnil 10 mg Tablet if you are allergic to any of its contents; if you are taking monoamine oxidase inhibitors (MOA) or have taken them in the last 14days, or if you are taking metoprolol (used to treat high blood pressure). Do not take Depnil 10 mg Tablet along with opioid antagonists such as buprenorphine and naloxone as it might lead to a serious condition called serotonin syndrome. Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself. Inform your doctor if you have/had epilepsy, mania, glaucoma, diabetes, bleeding disorders, or hyponatremia (low sodium levels).  Do not take Depnil 10 mg Tablet if you are pregnant or breastfeeding unless prescribed. Do not drive or operate machinery as Depnil 10 mg Tablet may cause dizziness and might impair your reactions. Depnil 10 mg Tablet should not be given to children below 8years as the safety and effectiveness have not been established. Avoid consuming alcohol along with Depnil 10 mg Tablet as it could lead to increased dizziness. 

Drug-Drug Interactions

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VortioxetineLinezolid
Critical
VortioxetineProcarbazine
Critical

Drug-Drug Interactions

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VortioxetineLinezolid
Critical
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Linezolid with Depnil 10 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Linezolid with Depnil 10 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
VortioxetineProcarbazine
Critical
How does the drug interact with Depnil 10 mg Tablet:
When Depnil 10 mg Tablet is taken with Procarbazine, it can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Procarbazine is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
VortioxetineSafinamide
Critical
How does the drug interact with Depnil 10 mg Tablet:
Taking Safinamide with Depnil 10 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Safinamide is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
VortioxetineVenlafaxine
Severe
How does the drug interact with Depnil 10 mg Tablet:
When Venlafaxine is combined with Depnil 10 mg Tablet, increases the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Venlafaxine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
VortioxetineDexfenfluramine
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet with Dexfenfluramine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Dexfenfluramine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
VortioxetineAlfentanil
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Alfentanil with Depnil 10 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Depnil 10 mg Tablet and Alfentanil, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
VortioxetineCitalopram
Severe
How does the drug interact with Depnil 10 mg Tablet:
Combining Depnil 10 mg Tablet with Citalopram can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Citalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to your doctor right away. Do not discontinue any medications without first consulting your doctor.
VortioxetineDextromethorphan
Severe
How does the drug interact with Depnil 10 mg Tablet:
Co-administration of Dextromethorphan with Depnil 10 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Co-administration of Depnil 10 mg Tablet with Dextromethorphan can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact a doctor. Do not stop using any medications without a doctor's advice.
VortioxetineNefazodone
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Depnil 10 mg Tablet with Nefazodone can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Depnil 10 mg Tablet with Nefazodone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
VortioxetineRasagiline
Severe
How does the drug interact with Depnil 10 mg Tablet:
Taking Rasagiline with Depnil 10 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Co-administration of Depnil 10 mg Tablet with rasagiline can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improving mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

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Depnil 10 mg Tablet Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Depnil 10 mg Tablet works by inhibiting the reuptake of serotonin by nerves, a mood-enhancing chemical messenger in the brain which communicates between brain cells. This helps in an increase in serotonin concentrations in the nerve synapse, thereby helps in regulating mood and treats depression.

Depnil 10 mg Tablet may cause weight loss due to loss of appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight. Please consult your doctor if you experience fluctuations in weight while taking Depnil 10 mg Tablet .

Do not discontinue Depnil 10 mg Tablet without consulting your doctor as it could lead to withdrawal effects. To treat your condition effectually continue taking Depnil 10 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Depnil 10 mg Tablet ; the doctor may reduce the dose gradually.

Depnil 10 mg Tablet may cause decreased sex-drive, problems with erection and orgasm. Consult your doctor if you have any concerns regarding this.

Dry mouth could be a side-effect of Depnil 10 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Please consult your doctor before taking Depnil 10 mg Tablet if you have glaucoma as it might cause increased pressure in the eye.

Consult tour doctor before taking Depnil 10 mg Tablet if you are diabetic as it might fluctuate blood glucose levels. Regular monitoring of blood sugar levels is advised if you are taking Depnil 10 mg Tablet . Talk to your doctor if you experience fluctuations in blood sugar levels.

Depnil 10 mg Tablet might increase the risk of bone fractures. Talk to your doctor before taking Depnil 10 mg Tablet if you have osteoporosis. Consult your doctor if you experience bone pain.

Drug-Drug Interactions Checker List

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Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, changes in appetite, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression. 

Obsessive-Compulsive Disorder (OCD): It is a mental disorder which is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions). 

Bulimia nervosa: It is a serious eating disorder which is characterised by binge eating followed by methods to avoid overweight such as vomiting, severe exercise or fasting.

Panic disorder: It is a type of anxiety disorder which causes panic attacks. In this condition, a person experiences a sudden feeling of fear, when, in reality, there is no danger. Symptoms include fast heartbeat, breathing difficulty, chest or stomach pain, weakness or dizziness, and sweating.

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