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  3. Depof 0.5/10 Tablet 10's

Not for online sale
Depof 0.5/10 Tablet 10's, Pack of 10 TABLETS
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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COD available

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Whats That

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Composition :

FLUPENTIXOL-0.50MG + MELITRACEN-10MG

Manufacturer/Marketer :

Talent India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Depof 0.5/10 Tablet

Depof 0.5/10 Tablet is primarily used to treat psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia, menopausal depression, depression in alcoholics and drug addicts. Depression is a mood disorder that affects a person's daily life and is described as feelings of sadness, loss, or anger. These symptoms may interfere with daily activities and affect the quality of life.

Depof 0.5/10 Tablet contains Flupentixol and Melitracen. Flupentixol is an antipsychotic medication that works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen is a tricyclic antidepressant that raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression. Thus, Depof 0.5/10 Tablet effectively treats various forms of depression and anxiety.

Take Depof 0.5/10 Tablet as prescribed. Your doctor will decide the dose and duration based on your medical condition. Common side effects of Depof 0.5/10 Tablet  include insomnia, restlessness, agitation, dizziness, tremor, dry mouth, constipation, accommodation disorder and fatigue. If any of these side effects persist or worsen, contact your doctor immediately. 

Do not use Depof 0.5/10 Tablet if you are allergic to any of the components. Seek medical advice if you are pregnant, planning to get pregnant, or breastfeeding. Do not consume alcohol while using Depof 0.5/10 Tablet as there may be an interaction. Depof 0.5/10 Tablet is not recommended for excitable or overactive patients since its activating effect may exaggerate these characteristics. The safety and efficacy of Depof 0.5/10 Tablet in children have not been established. Keep your doctor informed about your medical condition and medications to rule out any negative effects or interactions.

Uses of Depof 0.5/10 Tablet

Depression, anxiety, asthenia

Directions for Use

Take Depof 0.5/10 Tablet as prescribed by your doctor. Swallow the tablet as a whole with a glass of water. Do not crush, break or chew the tablet.

Medicinal Benefits

Depof 0.5/10 Tablet contains Flupentixol and Melitracen. Depof 0.5/10 Tablet is used to treat psychogenic depression, depressive neurosis, psychosomatic affections accompanied by anxiety and apathy, asthenia (abnormal physical weakness), menopausal depression, depression in alcoholics and drug addicts. Flupentixol is an antipsychotic medication. It works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen is a tricyclic antidepressant that raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression. 

Storage

Keep out of sight and reach of children.

Drug Warnings

Do not use Depof 0.5/10 Tablet if you are allergic to any of the components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Let your doctor know if you have circulatory collapse (specific failure of the blood circulation), depressed level of consciousness due to any cause (e.g. intoxication with alcohol, opiates or barbiturates), untreated narrow-angle glaucoma, coma, blood disorders, phaeochromocytoma (a small vascular tumour), recent myocardial infarction, any degree of atrioventricular block or disorders of cardiac rhythm and coronary artery insufficiency. Concomitant treatment of Depof 0.5/10 Tablet with MAOIs (monoamine oxidase inhibitors) is contraindicated as it may cause serotonin syndrome (a combination of symptoms, possibly including confusion, agitation, tremor, hyperthermia and myoclonus). Therefore, do not take Depof 0.5/10 Tablet if you are taking MAOIs or have taken them in the past 14 days.

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical
ImipramineSafinamide
Critical

Drug-Drug Interactions

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ChlordiazepoxideSodium oxybate
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Taking Depof 0.5/10 Tablet with Sodium oxybate increases the risk of breathing difficulty or low blood pressure.

How to manage the interaction:
Taking Depof 0.5/10 Tablet with Sodium oxybate is generally avoided as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience dizziness, shortness of breath, excessive sweating, or blurred vision, contact your doctor. Do not discontinue any medications without consulting a doctor.
ImipramineSafinamide
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Coadministration of Safinamide with Depof 0.5/10 Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking safinamide and Depof 0.5/10 Tablet together is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
ImipramineSparfloxacin
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Taking Sparfloxacin with Depof 0.5/10 Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sparfloxacin and Depof 0.5/10 Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePotassium citrate
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Taking Depof 0.5/10 Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Potassium citrate and Depof 0.5/10 Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ImipramineLinezolid
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Coadministration of Linezolid with Depof 0.5/10 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Linezolid and Depof 0.5/10 Tablet together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipraminePhenelzine
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Coadministration of Depof 0.5/10 Tablet with Phenelzine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Depof 0.5/10 Tablet and Phenelzine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineDronedarone
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Taking Depof 0.5/10 Tablet with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Depof 0.5/10 Tablet with Dronedarone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineZiprasidone
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Using ziprasidone together with Depof 0.5/10 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Depof 0.5/10 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
ImipramineSelegiline
Critical
How does the drug interact with Depof 0.5/10 Tablet:
Co-administration of Depof 0.5/10 Tablet with Selegiline might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Depof 0.5/10 Tablet and Selegiline together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ImipramineThioridazine
Critical
How does the drug interact with Depof 0.5/10 Tablet:
When Thioridazine and Depof 0.5/10 Tablet are taken together, the body's ability to break down Thioridazine may be reduced. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Depof 0.5/10 Tablet with Thioridazine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, or seizure, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Regularly attend treatment sessions.
  • Meditation and yoga help to relieve stress.
  • Maintain a consistent sleep schedule to increase the amount and quality of sleep you obtain.
  • Include omega-3 fatty acid-rich foods like fish, nuts, fresh fruits and vegetables, and olive oils in your diet.
  • Amino acids are the building blocks of neurotransmitters. Include foods high in amino acids, including meat, dairy products, and some fruits and vegetables as they aid in maintaining neurotransmitters.
  • Complex carbs such as whole grains, legumes, spinach, broccoli, oranges, and pears aid in the stimulation of serotonin (a feel-good neurotransmitter).
  • Exercising helps the body's natural antidepressant synthesis. It also aids in stress relief, mood enhancement, self-esteem enhancement, and comfortable sleep.
  • Avoid smoking and drinking alcohol.
  • Learn about your medical condition, be aware of the risk factors, and stick to your doctor's treatment plan.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Depof 0.5/10 Tablet Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Depof 0.5/10 Tablet contains Flupentixol and Melitracen. Flupentixol works by inhibiting dopamine, a chemical messenger in the brain that influences thoughts and mood. Melitracen raises the levels of chemical messengers in the brain that aid in mood regulation and the treatment of depression. Thus, Depof 0.5/10 Tablet effectively reduces the symptoms of depression.

Depof 0.5/10 Tablet should not be abruptly discontinued since this may worsen your symptoms. Consult your doctor if you experience any difficulty while taking Depof 0.5/10 Tablet .

Depof 0.5/10 Tablet is contraindicated for patients who have had a recent myocardial infarction, atrioventricular block of any degree, coronary artery insufficiency, or cardiac rhythm abnormalities.

Depof 0.5/10 Tablet works by acting on the brain's neurotransmitters to help regulate mood more effectively. Thereby, making you feel energetic and thus helping treat asthenia.

Depof 0.5/10 Tablet works by boosting the level of a neurotransmitter in the brain called serotonin. The higher the serotonin levels, the better the brain communicates. Thus, Depof 0.5/10 Tablet eases anxiety symptoms.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • PENTOBARBITAL
  • PHENOBARBITAL
  • DIAZEPAM
  • CLONAZEPAM
  • ALPRAZOLAM
  • THIORIDAZINE
  • CHLORPROMAZINE

Special Advise

While using this medication, strictly follow your doctor's recommendations. Even if you feel better, do not reduce or discontinue your medicine on your own. This may aggravate your condition.

 

Disease/Condition Glossary

Depression: It is a mood condition defined by a continuous feeling of unhappiness, dissatisfaction, hopelessness, anger or loss that interferes with a person's daily activities. Depression can also have an impact on some chronic health issues and relationships. Neurotransmitters such as serotonin, dopamine, and noradrenaline levels drop in this illness, resulting in depressive symptoms. The specific aetiology of depression is unknown; however, it may be linked to mental health issues, family history, drug use, trauma, and physiological diseases. Depression can be treated with medications and psychotherapy.

Anxiety: Anxiety is a state of uneasiness that can range from mild to severe. Anxiety is a normal emotion. However, some people struggle to keep their fears in control. Their worry is more persistent and frequently interferes with their daily life. Anxiety is the primary symptom of several disorders, including panic disorder, phobias (such as agoraphobia or claustrophobia), post-traumatic stress disorder (PTSD), and social anxiety disorder (social phobia).

Asthenia: It is a condition characterised by a lack of energy, strength, and physical or mental weakness which can affect certain body parts or the entire body.

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