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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Deriphyllin OD 450 Tablet

Deriphyllin OD 450 Tablet belongs to the class of drugs called bronchodilators used to prevent and treat symptoms of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Deriphyllin OD 450 Tablet contains Theophylline and Etofylline, that work by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier. Thereby, Deriphyllin OD 450 Tablet helps prevent and treat the symptoms of asthma and COPD.

Take Deriphyllin OD 450 Tablet as prescribed by your doctor. You are advised to take Deriphyllin OD 450 Tablet for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience nausea, vomiting, headache, restlessness, dizziness, irregular heartbeat, or stomach upset. Most of these side effects of Deriphyllin OD 450 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Deriphyllin OD 450 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Deriphyllin OD 450 Tablet . Do not take Deriphyllin OD 450 Tablet if you have a heart rhythm disorder. If your breathing worsens or you often wake up at night with asthma and experience chest tightness in the morning, please consult a doctor immediately, as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. 

Uses of Deriphyllin OD 450 Tablet

Asthma, chronic obstructive pulmonary disease (COPD)

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Deriphyllin OD 450 Tablet contains two bronchodilators, namely, Theophylline and Etofylline, used to treat symptoms of asthma and chronic obstructive pulmonary diseases (COPD). Deriphyllin OD 450 Tablet works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Deriphyllin OD 450 Tablet or any other medicines, please tell your doctor. If your breathing worsens or you often wake up at night with asthma, and experience chest tightness in the morning, please consult a doctor immediately as these might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Deriphyllin OD 450 Tablet as it may cause low potassium levels in the blood. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Deriphyllin OD 450 Tablet . Do not take Deriphyllin OD 450 Tablet if you have a heart rhythm disorder. Avoid taking Deriphyllin OD 450 Tablet if you have a history of a heart attack.

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
TheophyllineBupropion
Severe

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Deriphyllin OD 450 Tablet with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Deriphyllin OD 450 Tablet with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
TheophyllineBupropion
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Deriphyllin OD 450 Tablet with bupropion can increase the risk of seizures (fits).

How to manage the interaction:
Co-administration of bupropion along with Deriphyllin OD 450 Tablet can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any symptoms like Temporary confusion, A state of staring, Uncontrollable jerking movements of the arms and legs, Consciousness or awareness loss, Changes in cognition or emotion, consult a doctor. Do not discontinue any medications without consulting a doctor.
TheophyllinePropranolol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Using propranolol together with Deriphyllin OD 450 Tablet makes the propranolol less effective in controlling blood pressure, and it also increases the effects of Deriphyllin OD 450 Tablet

How to manage the interaction:
Although taking Propranolol together with Deriphyllin OD 450 Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
TheophyllineSotalol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking sotalol with Deriphyllin OD 450 Tablet, could reduce sotalol effects and increase the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although taking sotalol and Deriphyllin OD 450 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineLabetalol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking Labetalol with Deriphyllin OD 450 Tablet may reduce the effectiveness of Labetalol and increase Deriphyllin OD 450 Tablet's effects.

How to manage the interaction:
Although taking Labetalol and Deriphyllin OD 450 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sleeplessness, shaking, irregular heartbeats, or trouble breathing, consult a doctor. Do not discontinue any medications without a doctor's advice.
TheophyllineNebivolol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Combined use of Nebivolol with Deriphyllin OD 450 Tablet may increase the effect of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although there is a possible interaction between Deriphyllin OD 450 Tablet and Nebivolol, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, irregular heartbeats, contact a doctor. Do not discontinue any medications without a doctor's advice.
TheophyllineCarvedilol
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking carvedilol with Deriphyllin OD 450 Tablet, could make carvedilol less effective and increase the effects of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although Carvedilol and Deriphyllin OD 450 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, restlessness, palpitations, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineMexiletine
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Co-administration of Deriphyllin OD 450 Tablet with mexiletine can increase the effect of mexiletine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Deriphyllin OD 450 Tablet with Mexiletine can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, diarrhea, loss of appetite, headache, tremor, confusion, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineMetoprolol Tartrate
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking Metoprolol Tartrate with Deriphyllin OD 450 Tablet could make Metoprolol Tartrate less effective and increase the side effects of Deriphyllin OD 450 Tablet

How to manage the interaction:
Although taking metoprolol tartrate and Deriphyllin OD 450 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineDeferasirox
Severe
How does the drug interact with Deriphyllin OD 450 Tablet:
Taking deferasirox with Deriphyllin OD 450 Tablet may significantly increase the blood levels of Deriphyllin OD 450 Tablet.

How to manage the interaction:
Although taking deferasirox and Deriphyllin OD 450 Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as nausea, vomiting, diarrhea, loss of hunger, headache, shaking, confusion, restlessness, sleeplesness, fits, heart palpitations, and/or irregular heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ETOFYLLINE-346MG+THEOPHYLLINE-104MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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ETOFYLLINE-346MG+THEOPHYLLINE-104MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of caffeine-containing foods/drinks while on the treatment with Theophylline, Etofylline nicotinate can increase the risk of Theophylline, Etofylline nicotinate and cause nausea, vomiting, headache, loose stools, sleeplessness, shaking of hands and legs, fits, restlessness, increased or decreased heartbeat, or difficulty in breathing. Avoid or limit consumption of caffeine-containing foods/drinks while on the treatment with Theophylline, Etofylline nicotinate.

Diet & Lifestyle Advise

  • Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a deficiency in potassium may cause breathing problems.
  • Drink plenty of fluids as it h thin mucus and makes it easier to cough out.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice as it may worsen asthma symptoms.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of Deriphyllin OD 450 Tablet , irritate the lungs or worsen breathing problems.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

Deriphyllin OD 450 Tablet Substitute

Substitutes safety advice
  • Theot 346mg/104mg Tablet SR

    by Others

    7.20per tablet
  • Theot Tablet 10's

    by Others

    7.88per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Deriphyllin OD 450 Tablet works by relaxing muscles and widening the airways of the lungs. Thus, it makes breathing easier.

You are not recommended to take linezolid with Deriphyllin OD 450 Tablet as it may increase the risk of adverse effects of Deriphyllin OD 450 Tablet . However, please consult a doctor before using other medicines with Deriphyllin OD 450 Tablet .

You are recommended to avoid taking Deriphyllin OD 450 Tablet if you are allergic to theophylline, etofylline or are suffering from irregular heart rhythm, severe liver or kidney diseases or have a history of a heart attack. Inform your doctor if you have any of these conditions before taking Deriphyllin OD 450 Tablet .

You are not recommended to stop taking Deriphyllin OD 450 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Deriphyllin OD 450 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Deriphyllin OD 450 Tablet , please consult your doctor.

Deriphyllin OD 450 Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to always carry a rescue inhaler to treat sudden asthma symptoms.

Drug-Drug Interactions Checker List

  • DESIPRAMINE
  • AMITRIPTYLINE
  • AMOXAPINE
  • RITONAVIR
  • ERYTHROMYCIN
  • CIPROFLOXACIN
  • ENOXACIN
  • LINEZOLID
  • FLUCONAZOLE
  • CLOMIPRAMINE
  • RIFAMPICIN
  • ISONIAZID
  • CLARITHROMYCIN

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The treatment for asthma includes medication, breathing exercises, and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).

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