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Desferal 500 mg Injection 1's

Desferal 500 mg Injection 1's

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Prescription drug
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Manufacturer/Marketer

Novartis India Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Desferal 500 mg Injection 1's

Desferal 500 mg Injection 1's belongs to the group of medicines called ‘chelating agents’ used to remove excess iron from the body in anemia or chronic iron overload due to blood transfusions in patients 2 years of age and older. It is also used with other medicines to treat acute iron poisoning, especially in small children. Besides this, Desferal 500 mg Injection 1's may also be used for high aluminum levels in dialysis patients and people with aluminum poisoning.

Desferal 500 mg Injection 1's contains Deferoxamine an iron-binding agent that belongs to a class of medicines called heavy metal antagonists. It works by binding trivalent (ferric) iron which has a strong affinity, forming ferrioxamine, a stable complex that prevents the iron from entering into further chemical reactions and also is eliminated from the body. It helps the kidneys and gallbladder get rid of the extra iron.

Desferal 500 mg Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as flushing (sense of warmth in the face, ears, neck, and trunk), skin rash, hypotension (decreased pressure), change in color of urine to red, headache, upset stomach or throwing up, diarrhea, muscle or joint pain, irritation where the injection is given. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Desferal 500 mg Injection 1's for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Desferal 500 mg Injection 1's if you are pregnant or planning for pregnancy and breastfeeding unless prescribed by a doctor. Your doctor may advise you to undergo regular blood tests, kidney and liver tests, eye examinations, and hearing tests to monitor your condition. Avoid consuming alcohol along with Desferal 500 mg Injection 1's as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Desferal 500 mg Injection 1's

Iron Intoxication

Medicinal Benefits

Desferal 500 mg Injection 1's contains Deferoxamine an iron-chelating agent used for treating acute iron intoxication or emergency cases of iron poisoning. This medication can also be used to help get rid of iron in patients with high iron levels due to many blood transfusions. Desferal 500 mg Injection 1's works by forming a stable complex that prevents the iron and aluminum ions from entering into further chemical reactions and helping the kidneys and gallbladder eliminate the extra iron. This reduces the risk of organ damage.

Directions for Use

Desferal 500 mg Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Desferal 500 mg Injection 1's

  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Skin rash
  • Hypotension (decreased blood pressure) 
  • Change in color of urine to red
  • Headache
  • Abdominal pain
  • Upset stomach or throwing up
  • Diarrhea
  • Muscle or joint pain
  • Irritation where the injection is given

Drug Warnings

Do not take Desferal 500 mg Injection 1's if you are allergic to Deferoxamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems and are on dialysis, liver disease, rheumatoid arthritis, diabetes, and any fungal infection. Do not take Desferal 500 mg Injection 1's if you are pregnant or planning to get pregnant and breastfeeding unless prescribed by a doctor. Desferal 500 mg Injection 1's may affect growth in children (especially those younger than 3 years of age) and teens in some cases. They may need regular growth checkups while taking Desferal 500 mg Injection 1's. Your doctor may recommend to you regular eye tests and hearing tests. Desferal 500 mg Injection 1's can affect your vision and your hearing.  Older adults (65 or older) may be more sensitive to the side effects of Desferal 500 mg Injection 1's, especially vision/hearing problems. Talk with your doctor before taking multivitamins, natural products, and diet aids. If you are using Desferal 500 mg Injection 1's to treat high iron levels, your doctor may advise you to take vitamin C (ascorbic acid) after using this medication for at least 1 month. Taking vitamin C will help replace vitamin C loss due to high iron levels and help the medication work to get rid of the iron. If you have a heart problem (heart failure), Desferal 500 mg Injection 1's should not be used with vitamin C (ascorbic acid) because severe interactions may occur. This medicine may affect certain lab tests. Inform your doctor and lab staff that you take Desferal 500 mg Injection 1's. If you are using Desferal 500 mg Injection 1's for aluminum poisoning, inform your doctor if you have seizures (fits), hypocalcemia (decreased calcium level in blood), and hyperparathyroidism.

Drug Interactions

Drug-Drug Interactions: Desferal 500 mg Injection 1's interacts with a medicine used to treat anxiety or schizophrenia (prochlorperazine), a medicine used to treat anemia (erythropoietin), antacids (aluminum hydroxide, aluminum carbonate), a medicine used to treat asthma (theophylline), antiviral (tenofovir, cidofovir), a contrast agent used during X-rays (diatrizoate), a medication used for the treatment of nerve damage (inotersen), radiocontrast agent (metrizamide), a diagnostic contrast agent (ioxilan), a medication used to treat epilepsy (vigabatrin).

Drug-Food Interactions: No interaction found.

Drug-Disease Interactions: Desferal 500 mg Injection 1's should not be used in people with renal dysfunction, auditory dysfunction, hepatic impairment, ocular dysfunction, or respiratory distress syndrome.

Drug-Drug Interactions Checker List

  • PROCHLORPERAZINE
  • ERYTHROPOIETIN
  • ALUMINIUM HYDROXIDE
  • THEOPHYLLINE
  • TENOFOVIR DISOPROXIL
  • CIDOFOVIR
  • VIGABATRIN
  • INOTERSEN
  • DIATRIZOATE
  • IOXILAN
  • METRIZAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • It is essential to follow a specific diet plan created by your nutritionist to control health condition.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Your doctor may advise you to take blood and urine tests while using Desferal 500 mg Injection 1's to examine your health condition and ensure that this medicine treats your condition.
  • Eye examination and hearing tests are recommended while using Desferal 500 mg Injection 1's to affect your vision and hearing.
  • X-rays or scan results may be affected by treatment with Desferal 500 mg Injection 1's. Inform your doctor that you are being treated with Desferal 500 mg Injection 1's if an X-ray or scan is suggested.

Disease/Condition Glossary

Iron intoxication: Iron poisoning occurs from the ingestion of excess iron or increases iron levels in the blood that results in acute toxicity. Excessive iron can be damaging to the gastrointestinal system.  Iron is an essential mineral for blood production. Symptoms of iron toxicity include nausea, vomiting, diarrhea, and stomach pain. Iron can also accumulate in the organs and cause fatal damage to the liver or brain.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - DES0030

FAQs

Desferal 500 mg Injection 1's is an antidote that is used in the treatment of acute iron poisoning. It contains Deferoxamine which removes excess iron from the body, which is then excreted mainly in the stools. This reduces the risk of organ damage.
Desferal 500 mg Injection 1's should not be used in people with any fungal infections, clouding the eye's lens (cataracts), ringing in the ears, liver disease, seizures, and heart problems. It should also be used with extreme caution in people with severe kidney impairment as this medicine may cause kidney damage.
Iron poisoning is treatable, and you can survive this condition with a quick diagnosis and accurate treatment.
Desferal 500 mg Injection 1's may cause side-effects such as pain, redness, swelling at the injection site, flushing (sense of warmth in the face, ears, neck, and trunk), rash, decreased blood pressure, abdominal pain. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Yes, Desferal 500 mg Injection 1's can cause abnormal liver or renal function test results. X-rays or scans results may also be affected by treatment with Desferal 500 mg Injection 1's. Ensure that the doctor or nurse knows that you are being treated with Desferal 500 mg Injection 1's if a laboratory test and X-ray or scan is suggested.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

It is not known whether the Desferal 500 mg Injection 1's can interact with alcohol. However, you are recommended not to consume alcohol along with Desferal 500 mg Injection 1's to avoid unpleasant side-effects.

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Pregnancy

Caution

Desferal 500 mg Injection 1's is a pregnancy Category B medicine. It may not cause harm to an unborn fetus. However, Desferal 500 mg Injection 1's should be taken only when prescribed by a doctor only if he/she thinks benefits outweigh the risks.

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Breast Feeding

Caution

Desferal 500 mg Injection 1's should be used in breastfeeding mothers only if the benefits outweigh the risks as there is insufficient data available regarding the use of this medicine in breastfeeding mothers.

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Driving

Caution

After taking this drug, you can experience side effects like feeling dizzy, tired or alter your vision. If this occurs, do not drive or perform any work that requires a high level of concentration.

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Liver

Caution

Desferal 500 mg Injection 1's to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-colored urine, or yellowing of skin/eye.

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Kidney

Caution

Desferal 500 mg Injection 1's should be used with caution in patients with renal impairment since the metal complexes are excreted via the kidneys. In these patients, dialysis will increase the elimination of chelated iron and aluminum. So, it should be used with caution in patients with kidney diseases. The dose may have to be adjusted by the doctor.

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Children

Safe if prescribed

In children below the age of 3 years, Desferal 500 mg Injection 1's may affect the growth. Regular checks on body weight and height are, therefore, recommended in children using Desferal 500 mg Injection 1's.

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