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About Desferal 500 mg Injection
Desferal 500 mg Injection belongs to the group of medicines called ‘chelating agents’ used to remove excess iron from the body in anemia or chronic iron overload due to blood transfusions in patients 2 years of age and older. It is also used with other medicines to treat acute iron poisoning, especially in small children. Besides this, Desferal 500 mg Injection may also be used for high aluminum levels in dialysis patients and people with aluminum poisoning.
Desferal 500 mg Injection contains Deferoxamine an iron-binding agent that belongs to a class of medicines called heavy metal antagonists. It works by binding trivalent (ferric) iron which has a strong affinity, forming ferrioxamine, a stable complex that prevents the iron from entering into further chemical reactions and also is eliminated from the body. It helps the kidneys and gallbladder get rid of the extra iron.
Desferal 500 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as flushing (sense of warmth in the face, ears, neck, and trunk), skin rash, hypotension (decreased pressure), change in color of urine to red, headache, upset stomach or throwing up, diarrhea, muscle or joint pain, irritation where the injection is given. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
To treat your condition effectually, continue taking Desferal 500 mg Injection for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Desferal 500 mg Injection if you are pregnant or planning for pregnancy and breastfeeding unless prescribed by a doctor. Your doctor may advise you to undergo regular blood tests, kidney and liver tests, eye examinations, and hearing tests to monitor your condition. Avoid consuming alcohol along with Desferal 500 mg Injection as it could lead to increased drowsiness and dizziness. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Uses of Desferal 500 mg Injection
Directions for Use
Medicinal Benefits
Desferal 500 mg Injection contains Deferoxamine an iron-chelating agent used for treating acute iron intoxication or emergency cases of iron poisoning. This medication can also be used to help get rid of iron in patients with high iron levels due to many blood transfusions. Desferal 500 mg Injection works by forming a stable complex that prevents the iron and aluminum ions from entering into further chemical reactions and helping the kidneys and gallbladder eliminate the extra iron. This reduces the risk of organ damage.
Storage
Drug Warnings
Do not take Desferal 500 mg Injection if you are allergic to Deferoxamine or any of the other ingredients in it. Inform your doctor if you have severe kidney problems and are on dialysis, liver disease, rheumatoid arthritis, diabetes, and any fungal infection. Do not take Desferal 500 mg Injection if you are pregnant or planning to get pregnant and breastfeeding unless prescribed by a doctor. Desferal 500 mg Injection may affect growth in children (especially those younger than 3 years of age) and teens in some cases. They may need regular growth checkups while taking Desferal 500 mg Injection. Your doctor may recommend to you regular eye tests and hearing tests. Desferal 500 mg Injection can affect your vision and your hearing. Older adults (65 or older) may be more sensitive to the side effects of Desferal 500 mg Injection, especially vision/hearing problems. Talk with your doctor before taking multivitamins, natural products, and diet aids. If you are using Desferal 500 mg Injection to treat high iron levels, your doctor may advise you to take vitamin C (ascorbic acid) after using this medication for at least 1 month. Taking vitamin C will help replace vitamin C loss due to high iron levels and help the medication work to get rid of the iron. If you have a heart problem (heart failure), Desferal 500 mg Injection should not be used with vitamin C (ascorbic acid) because severe interactions may occur. This medicine may affect certain lab tests. Inform your doctor and lab staff that you take Desferal 500 mg Injection. If you are using Desferal 500 mg Injection for aluminum poisoning, inform your doctor if you have seizures (fits), hypocalcemia (decreased calcium level in blood), and hyperparathyroidism.
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Desferal 500 mg Injection is an antidote that is used in the treatment of acute iron poisoning. It contains Deferoxamine which removes excess iron from the body, which is then excreted mainly in the stools. This reduces the risk of organ damage.
Desferal 500 mg Injection should not be used in people with any fungal infections, clouding the eye's lens (cataracts), ringing in the ears, liver disease, seizures, and heart problems. It should also be used with extreme caution in people with severe kidney impairment as this medicine may cause kidney damage.
Iron poisoning is treatable, and you can survive this condition with a quick diagnosis and accurate treatment.
Desferal 500 mg Injection may cause side-effects such as pain, redness, swelling at the injection site, flushing (sense of warmth in the face, ears, neck, and trunk), rash, decreased blood pressure, abdominal pain. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Yes, Desferal 500 mg Injection can cause abnormal liver or renal function test results. X-rays or scans results may also be affected by treatment with Desferal 500 mg Injection. Ensure that the doctor or nurse knows that you are being treated with Desferal 500 mg Injection if a laboratory test and X-ray or scan is suggested.
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Special Advise
Disease/Condition Glossary
Iron intoxication: Iron poisoning occurs from the ingestion of excess iron or increases iron levels in the blood that results in acute toxicity. Excessive iron can be damaging to the gastrointestinal system. Iron is an essential mineral for blood production. Symptoms of iron toxicity include nausea, vomiting, diarrhea, and stomach pain. Iron can also accumulate in the organs and cause fatal damage to the liver or brain.
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