Desifer 400 mg Tablet 6's
MRP ₹506
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₹75.9 Cashback (15%)
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About Desifer 400 mg Tablet
Desifer 400 mg Tablet belongs to the group of medicines called iron chelators. Desifer 400 mg Tablet is indicated for treating chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients two years older. It can also be indicated for treating chronic iron overload in patients ten years of age and older with non-transfusion-dependent thalassemia (NTDT).
The active ingredient in Desifer 400 mg Tablet is deferasirox. It is a trivalent iron selective chelating agent. It binds the excess iron and eliminates it through faeces. The danger of organ damage is reduced as a result.
Desifer 400 mg Tablet is available in the form of oral formulations. Please take Desifer 400 mg Tablet in the dose and duration prescribed by your doctor based on specific medical conditions. In some cases, you may experience common side effects such as diarrhoea, vomiting, nausea, abdominal pain, skin rashes, and increased serum creatinine. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
To treat your condition effectually, continue using Desifer 400 mg Tablet for as long as your doctor has prescribed it. Do not use Desifer 400 mg Tablet without a doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Desifer 400 mg Tablet if you are pregnant or breastfeeding. Do not use Desifer 400 mg Tablet in more than prescribed doses or longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Desifer 400 mg Tablet to rule out any side effects.
Uses of Desifer 400 mg Tablet
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Directions for Use
Key Benefits
Deferasirox is the active component in Desifer 400 mg Tablet. It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.
Storage
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Increased creatinine levels must be corrected immediately with the help of a doctor.
- Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
- Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
- Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
- Avoid smoking and drinking alcohol.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Preventing Vomiting (Before it Happens)
- Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
- Having a small meal before taking your medication can help reduce nausea and vomiting.
- Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
- Managing Vomiting (If it Happens)
- Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
- What to Do if Vomiting Persists
- Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
- Inform your doctor immediately if you experience a fever after starting a new medication.
- Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
- Monitor your body temperature to monitor fever progression.
- Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
- Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
- Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
- If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Drug Warnings
Do not take Desifer 400 mg Tablet if you are allergic to Desifer 400 mg Tablet or its ingredients. Desifer 400 mg Tablet is not usually recommended if you are a pregnant or lactating woman; there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the medicine's benefits outweigh the risks. It is unknown whether Desifer 400 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer. Avoid consuming alcohol along with Desifer 400 mg Tablet as it could lead to unpleasant side effects. Should monitor elderly and paediatric patients closely for toxicity.
Drug-Drug Interactions
Drug-Drug Interactions
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Desifer 400 mg Tablet may cause kidney problems and combining it with bacitracin may increase that risk.
How to manage the interaction:
Although taking Bacitracin and Desifer 400 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Co-administration of Desifer 400 mg Tablet with Betamethasone might increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although there is an interaction, Betamethasone can be taken with Desifer 400 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of gastrointestinal injury such as abdominal pain, bloating, lightheadedness, dizziness, nausea, loss of appetite, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not discontinue any medication without consulting a doctor.
Desifer 400 mg Tablet may cause kidney problems and combining it with capreomycin may increase that risk.
How to manage the interaction:
Although taking Capreomycin and Desifer 400 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Taking Dexamethasone with Desifer 400 mg Tablet may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Desifer 400 mg Tablet if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of gastrointestinal injury such as abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools. Do not discontinue the medication without consulting a doctor.
Taking tacrolimus with Desifer 400 mg Tablet can increase the risk of kidney problems.
How to manage the interaction:
Although taking tacrolimus and Desifer 400 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
Coadministration of Vancomycin with Desifer 400 mg Tablet can increase the risk or severity of kidney problems.
How to manage the interaction:
Although taking Vancomycin with Desifer 400 mg Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
Coadministration of Desifer 400 mg Tablet and Sulfasalazine may increase the risk or severity of kidney problems.
How to manage the interaction:
Although taking sulfasalazine and Desifer 400 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
Coadministration of Warfarin with Desifer 400 mg Tablet may increase the risk of gastrointestinal ulcers and bleeding.
How to manage the interaction:
There may be a possible interaction between Desifer 400 mg Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience abdominal pain, bloating, dizziness, lightheadedness, loss of appetite, nausea, vomiting (especially with fresh or dried blood that looks like coffee grounds), and red or black, tarry stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Desifer 400 mg Tablet and ketorolac may increase the risk of bleeding and stomach ulcers.
How to manage the interaction:
Although taking Ketorolac and Desifer 400 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe abdominal pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (particularly with blood), appetite loss, or black, tarry stools, increased or decreased urination, fluid retention, swelling, breathlessness, muscle cramps, weakness, confusion, and irregular heartbeat, consult a doctor contact your doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Mefenamic acid with Desifer 400 mg Tablet can increase the risk or severity of gastric bleeding.
How to manage the interaction:
Taking Mefenamic acid with Desifer 400 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
The blood levels and effects of caffeine may be enhanced by Desifer 400 mg Tablet. Avoid consumption of caffeinated drinks during the treatment with Desifer 400 mg Tablet. If you experience any unusual symptoms call a doctor.
Diet & Lifestyle Advise
- Choose foods high in nutrients, such as fruits, vegetables, and whole grains.
- Replace fatty protein sources with lean alternatives and consume modest quantities of healthy fat sources for improved well-being.
- Create a diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
- Instead of saturated and trans fats, choose monounsaturated and polyunsaturated fats (fish, nuts, and vegetable oils).
- Select/prepare foods and beverages with fewer added sugars/caloric sweeteners.
- Be mindful of salt; consume no more than 2,300 mg each day.
- Limit or avoid alcohol and caffeine consumption.
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Alcohol
Safe if prescribed
Consume alcohol along with Desifer 400 mg Tablet is not advisable as it may cause unpleasant side effects, or you also may become more sensitive to the effects of alcohol.
Pregnancy
Consult your doctor
Desifer 400 mg Tablet is not usually recommended if you are pregnant. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks. Please consult the doctor.
Breast Feeding
Consult your doctor
Desifer 400 mg Tablet is not usually recommended if you are a lactating woman. This is because there is not enough information to say whether it's safe. However, your doctor may prescribe it if they think the benefits of the medicine outweigh the risks.
Driving
Safe if prescribed
It is not known whether Desifer 400 mg Tablet alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.
Liver
Consult your doctor
Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Consult your doctor
Should exercise caution, and it is advisable to consult a doctor before using it. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
Should be used under the supervision of healthcare provider
FAQs
Deferasirox is the active component in Desifer 400 mg Tablet. It's a chelating agent that selectively binds to trivalent iron. It binds extra iron and excretes it in the faeces. As a result, the risk of organ damage is lowered.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.
Desifer 400 mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It can cause severe damage to your body, including to your heart, liver and pancreas.
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