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  1. Home
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  3. Develflex-XR 50 mg Tablet 10's

Develflex-XR 50 mg Tablet 10's, Pack of 10 TabletS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Whats That

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Composition :

DESVENLAFAXINE-50MG

Manufacturer/Marketer :

Talent India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Develflex-XR 50 mg Tablet

Develflex-XR 50 mg Tablet belongs to a group of medications called 'antidepressants' used to treat a major depressive disorder (depression). Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking.
 
Develflex-XR 50 mg Tablet contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance and helps in regulating mood, and treats depression. 
 
You are advised to take Develflex-XR 50 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Develflex-XR 50 mg Tablet suddenly, as it might cause withdrawal symptoms. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving as Develflex-XR 50 mg Tablet may cause sleepiness and dizziness. Develflex-XR 50 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Develflex-XR 50 mg Tablet as it could lead to increased sleepiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Develflex-XR 50 mg Tablet

Depression

Directions for Use

Take Develflex-XR 50 mg Tablet with or without food. Swallow Develflex-XR 50 mg Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Develflex-XR 50 mg Tablet belongs to a group of antidepressant medicines indicated for the treatment of a major depressive disorder. Develflex-XR 50 mg Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance and helps in regulating mood, and treats depression. 

Storage

Keep Develflex-XR 50 mg Tablet out of reach and sight of children.
Side effects of Develflex-XR 50 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.

Drug Warnings

Do not take Develflex-XR 50 mg Tablet if you are allergic to any of its contents; if you are taking linezolid, intravenous methylene blue, other serotonergic agents, monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days. Inform your doctor before taking Develflex-XR 50 mg Tablet if you have heart problems, hypotension, bipolar disorder, glaucoma, epilepsy, lung or breathing problems, bleeding problems, or low sodium levels in the blood. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Develflex-XR 50 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Develflex-XR 50 mg Tablet as it could lead to increased sleepiness and dizziness. 

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateVorinostat
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Develflex-XR 50 mg Tablet:
Combining Sodium phenylbutyrate and Develflex-XR 50 mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Develflex-XR 50 mg Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Vorinostat with Develflex-XR 50 mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Develflex-XR 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Develflex-XR 50 mg Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Develflex-XR 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Using buprenorphine together with Develflex-XR 50 mg Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Develflex-XR 50 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Ketamine and Develflex-XR 50 mg Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Develflex-XR 50 mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Leflunomide and Develflex-XR 50 mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Develflex-XR 50 mg Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Lithium with Develflex-XR 50 mg Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Develflex-XR 50 mg Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Meropenam and Develflex-XR 50 mg Tablet together can reduce the effect of Develflex-XR 50 mg Tablet.

How to manage the interaction:
Co-administration of Meropenam and Develflex-XR 50 mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
Co-administration of Teriflunomide and Develflex-XR 50 mg Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Develflex-XR 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Develflex-XR 50 mg Tablet:
The combined use of Ertapenem and Develflex-XR 50 mg Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Develflex-XR 50 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improves mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Side Effects of Develflex-XR 50 mg Tablet

  • Nausea
  • Dizziness 
  • Insomnia (sleeplessness)
  • Constipation
  • Sleepiness 
  • Loss of appetite 
  • Anxiety 
  • Sweating
  • Erectile dysfunction

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Develflex-XR 50 mg Tablet Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:32 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Develflex-XR 50 mg Tablet works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain which maintain mental balance, thereby regulating mood that treats depression.

Do not discontinue Develflex-XR 50 mg Tablet without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking Develflex-XR 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Develflex-XR 50 mg Tablet .

Develflex-XR 50 mg Tablet may cause decreased sex-drive (libido), problems with ejaculation and orgasm. Consult your doctor if you have any concerns regarding this.

Hypertension should be controlled before starting treatment with Develflex-XR 50 mg Tablet . Therefore, consult your doctor if you have high blood pressure. Regular monitoring of blood pressure levels is advised while taking Develflex-XR 50 mg Tablet .

Develflex-XR 50 mg Tablet may increase the chances of bleeding and bruising. The risk increases when Develflex-XR 50 mg Tablet is taken along with painkillers and blood thinners. Consult your doctor if you notice unusual bleeding or bruising.

When taken along with other medicines, Develflex-XR 50 mg Tablet may cause rare but potentially life-threatening condition called serotonin syndrome. This condition causes changes in how the brain, blood vessels, muscles and digestive system work. Avoid taking Develflex-XR 50 mg Tablet along with MAOI’s (used to treat depression), linezolid, intravenous methylene blue and other serotonergic agents.

Develflex-XR 50 mg Tablet may dilate your pupils (widen the dark centres of your eyes). This can trigger a glaucoma attack. Before taking Develflex-XR 50 mg Tablet , consult your doctor if you have glaucoma.

Develflex-XR 50 mg Tablet may cause seizures. If you’ve ever had a seizure, tell your doctor before taking Develflex-XR 50 mg Tablet .

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • AMPHETAMINE
  • DEXTROAMPHETAMINE
  • AMITRIPTYLINE
  • BUPROPION
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • TRAZODONE
  • VENLAFAXINE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • CYCLOBENZAPRINE
  • IBUPROFEN
  • TRAMADOL
  • ALPRAZOLAM
  • CETIRIZINE
  • PHENTERMINE
  • LISDEXAMFETAMINE

Special Advise

  • Do not stop taking Develflex-XR 50 mg Tablet suddenly as it might cause withdrawal symptoms.
  • Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself.
  • Talk to your doctor right away if you notice any unusual bleeding or bruising.

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Develflex-XR 50 mg Tablet as it may cause increased sleepiness and dizziness.

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Pregnancy

Caution

Develflex-XR 50 mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning for pregnancy, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Develflex-XR 50 mg Tablet may pass into breastmilk. Consult your doctor before taking Develflex-XR 50 mg Tablet your doctor will decide whether Develflex-XR 50 mg Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Develflex-XR 50 mg Tablet causes sleepiness and dizziness. Do not drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Develflex-XR 50 mg Tablet should not be given to children as safety and effectiveness have not been established.

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