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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Medbeat Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

About Diclobet-SP Tablet

Diclobet-SP Tablet belongs to the class of combination medication called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints which causes pain and joint stiffness.

Diclobet-SP Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent thereby decreasing swelling at the painful site. 
 
You are advised to take Diclobet-SP Tablet for as long as your doctor has prescribed it for you. In some cases, Diclobet-SP Tablet may cause certain common side-effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Diclobet-SP Tablet may cause drowsiness and dizziness, so drive with caution. Diclobet-SP Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Diclobet-SP Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Diclobet-SP Tablet

Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Directions for Use

Take Diclobet-SP Tablet with food. Swallow Diclobet-SP Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Diclobet-SP Tablet is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Diclobet-SP Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Diclobet-SP Tablet increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reduces inflammation. 

Storage

Keep Diclobet-SP Tablet out of reach and sight of children.
Side effects of Diclobet-SP Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Do not take Diclobet-SP Tablet if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Diclobet-SP Tablet may cause drowsiness and dizziness, so drive only if you are alert. Diclobet-SP Tablet is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Diclobet-SP Tablet as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Diclobet-SP Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Diclobet-SP Tablet unless prescribed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Diclobet-SP Tablet:
Co-administration of Diclobet-SP Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Diclobet-SP Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
How does the drug interact with Diclobet-SP Tablet:
Taking Diclobet-SP Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Diclobet-SP Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Diclobet-SP Tablet:
Co-administration use of Diclobet-SP Tablet with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Diclobet-SP Tablet and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Diclobet-SP Tablet:
Taking Diclobet-SP Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Diclobet-SP Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Diclobet-SP Tablet:
Coadministration of Diclobet-SP Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diclobet-SP Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Diclobet-SP Tablet:
Coadministration of Diclobet-SP Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Diclobet-SP Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Diclobet-SP Tablet:
Concomitant use of Diclobet-SP Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Diclobet-SP Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Diclobet-SP Tablet:
Concomitant administration of Diclobet-SP Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Diclobet-SP Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Diclobet-SP Tablet:
Taking prasugrel together with Diclobet-SP Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Diclobet-SP Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Diclobet-SP Tablet:
Co-administration of Diclobet-SP Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Diclobet-SP Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Side Effects of Diclobet-SP Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Headache

Habit Forming

No

Therapeutic Class

ANALGESICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Diclobet-SP Tablet contains Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase is a protein enzyme that helps break down and dissolves the abnormal proteins at the inflammation site, thereby reducing pain.

Diclobet-SP Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Diarrhoea might be a side-effect of Diclobet-SP Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Diclobet-SP Tablet should not be taken for longer durations unless prescribed by the doctor. If Diclobet-SP Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

Avoid taking Diclobet-SP Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CYCLOSPORINE
  • TACROLIMUS
  • LITHIUM
  • DIGOXIN
  • WARFARIN
  • METHOTREXATE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • MICONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • AMIDODARONE
  • SULFINPYRAZONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • CHLORAMPHENICOL
  • MIFEPRESTONE

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Diclobet-SP Tablet as it may cause increased drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Diclobet-SP Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Diclobet-SP Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Diclobet-SP Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Diclobet-SP Tablet should not be given to children less than 10 years of age, as the safety and effectiveness have not been established.

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