Diclomol SP 10 Tablet 10's

Written By Divya L , PharmaD

Reviewed By Santoshini Reddy G , M Pharmacy

MRP ₹114

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About Diclomol SP 10 Tablet

Diclomol SP 10 Tablet is a combination medicine used to treat pain and inflammation. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for a longer duration caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Diclomol SP 10 Tablet contains Diclofenac sodium and Serratiopeptidase. Diclofenac sodium works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which cause pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme that helps in the breakdown of fibrin, a by-product of blood clots into smaller units. It also promotes fluid drainage in the swollen tissue. Together, Diclomol SP 10 Tablet treats pain and inflammation.

Take Diclomol SP 10 Tablet as prescribed. Your doctor will advise you how often you take Diclomol SP 10 Tablet based on your medical condition. Common side effects of Diclomol SP 10 Tablet include stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Diclomol SP 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Diclomol SP 10 Tablet if you are allergic to any of the ingredients. It is not recommended for use in children. Diclomol SP 10 Tablet may be associated with a small increased risk of heart attack/myocardial infarction; therefore, inform your doctor if you have/had heart problems. Consult your doctor before taking Diclomol SP 10 Tablet if you are pregnant or breastfeeding. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Diclomol SP 10 Tablet

Pain and inflammation.

Directions for Use

Take Diclomol SP 10 Tablet during or after the meal to minimize symptoms of stomach upset or irritation. Swallow it as a whole with water. Do not chew, crush or break it.

Medicinal Benefits

Diclomol SP 10 Tablet relieves pain and inflammation. It is composed of Diclofenac sodium and Serratiopeptidase. Diclofenac sodium plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Serratiopeptidase is a proteolytic enzyme that helps in the breakdown of fibrin, a by-product of blood clots, into smaller units. It also promotes fluid drainage in the swollen tissue. Together, Diclomol SP 10 Tablet helps provide relief from pain and inflammation.

Storage

Keep out of sight and reach of children.

Side effects of Diclomol SP 10 Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

If you have a severe allergy to painkillers and complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, consult your doctor before taking Diclomol SP 10 Tablet . Consumption of alcohol should be avoided during the treatment with Diclomol SP 10 Tablet as it may lead to unpleasant side effects. Patients with stomach ulcers, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Diclomol SP 10 Tablet . Besides this, it should be avoided during the last trimester of pregnancy unless advised otherwise by a doctor. Do not drive or operate heavy machinery as intake of Diclomol SP 10 Tablet may cause dizziness. Patients who have recently undergone heart bypass surgery should take Diclomol SP 10 Tablet with caution and only under medical supervision.

Drug-Drug Interactions

DiclofenacMeloxicam

Critical

DiclofenacBromfenac

Severe

Drug-Drug Interactions

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DiclofenacMeloxicam

Critical

How does the drug interact with Diclomol SP 10 Tablet:
Co-administration of Diclomol SP 10 Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Diclomol SP 10 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.

DiclofenacBromfenac

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Taking Diclomol SP 10 Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Diclomol SP 10 Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacFlurbiprofen

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Co-administration use of Diclomol SP 10 Tablet with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Diclomol SP 10 Tablet and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacIbrutinib

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Taking Diclomol SP 10 Tablet with Ibrutinib can increase the risk of bleeding tendencies.

How to manage the interaction:
There may be a possible interaction between Diclomol SP 10 Tablet and Ibrutinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, or severe headaches. Do not discontinue any medications without consulting a doctor.

DiclofenacNaproxen

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Coadministration of Diclomol SP 10 Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diclomol SP 10 Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

DiclofenacCidofovir

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Coadministration of Diclomol SP 10 Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Diclomol SP 10 Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

DiclofenacDabigatran etexilate

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Concomitant use of Diclomol SP 10 Tablet with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Diclomol SP 10 Tablet with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacFurosemide

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Concomitant administration of Diclomol SP 10 Tablet and furosemide may decrease the therapeutic efficacy of furosemide and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between Diclomol SP 10 Tablet and furosemide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.

DiclofenacPrasugrel

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Taking prasugrel together with Diclomol SP 10 Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Diclomol SP 10 Tablet and Prasugrel can lead to an interaction; it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

DiclofenacDeferasirox

Severe

How does the drug interact with Diclomol SP 10 Tablet:
Co-administration of Diclomol SP 10 Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Diclomol SP 10 Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
Do not go for heavy exercise as it may increase joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle by lifting light weights.
In the chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which ramp up inflammation.
Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Side Effects of Diclomol SP 10 Tablet

Stomach ache
Diarrhoea
Nausea (feeling sick)
Indigestion

Habit Forming

No

Therapeutic Class

ANALGESICS

Diclomol SP 10 Tablet Substitute

Emanzen-D Tablet 10's

by Others

₹22.91per tablet

Flamit Plus Tablet 10's

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₹7.65per tablet

Author Details

Written By

Divya L

PharmaD

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:42 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Diclomol SP 10 Tablet work?

Diclomol SP 10 Tablet contains Diclofenac sodium and Serratiopeptidase. Diclofenac sodium works by blocking the release of chemical messengers which cause pain and fever. Serratiopeptidase helps in the breakdown of fibrin, a by-product of blood clots into smaller units. It also promotes fluid drainage in the swollen tissue. Together, Diclomol SP 10 Tablet helps provide relief from pain and inflammation.

Is Diclomol SP 10 Tablet used to relieve arthritic pain?

Diclomol SP 10 Tablet may be used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Can I take Diclomol SP 10 Tablet for longer durations?

Diclomol SP 10 Tablet should not be taken for longer durations unless prescribed by the doctor. If Diclomol SP 10 Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

I have stomach ulcers. Can I take Diclomol SP 10 Tablet ?

Avoid taking Diclomol SP 10 Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.

Does Diclomol SP 10 Tablet affect fertility?

Diclomol SP 10 Tablet contains diclofenac sodium which might impair female fertility. Therefore, if you are planning for pregnancy, avoid taking Diclomol SP 10 Tablet . Please consult your doctor, he/she may prescribe alternate medicine.

Drug-Drug Interactions Checker List

NIMESULIDE
OXYPHENBUTAZONE
METAMIZOLE
METHOTREXATE
WARFARIN
LITHIUM

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time, caused by damage to the tissues of the muscle, bone, or other organs. Chronic pain lasts for a longer duration and is caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal.