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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Whats That

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Composition :

PIROXICAM-20MG

Manufacturer/Marketer :

Biowell Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Diodex-20 Tablet

Diodex-20 Tablet belongs to the group of medications known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) used to relieve symptoms like pain, inflammation and joint stiffness associated with rheumatoid arthritis and osteoarthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Diodex-20 Tablet contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Diodex-20 Tablet as prescribed. In some cases, you may experience certain common side-effects such as diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side-effects persistently.

Diodex-20 Tablet can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not take Diodex-20 Tablet unless prescribed by the doctor. Diodex-20 Tablet increases the chances of stomach ulcers and bleeding. Consult your doctor before taking Diodex-20 Tablet if you are pregnant or breastfeeding. Diodex-20 Tablet may cause dizziness, so drive with caution. Diodex-20 Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Diodex-20 Tablet as it could lead to increased dizziness. It could also increase the risk of stomach bleeding.

Uses of Diodex-20 Tablet

Osteoarthritis, Rheumatoid arthritis

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, break, or crush the tablet/capsule.Dispersible tablet: Disperse the tablet in boiled and cooled water, stir well and consume immediately.

Medicinal Benefits

Diodex-20 Tablet belongs to the group of pain killers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Diodex-20 Tablet is used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. Diodex-20 Tablet works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight
Side effects of Diodex-20 Tablet
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

Diodex-20 Tablet may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Diodex-20 Tablet . Besides this, Diodex-20 Tablet may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take Diodex-20 Tablet if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase your risk of a heart attack or stroke. Consult your doctor before taking Diodex-20 Tablet if you are pregnant or breastfeeding. Diodex-20 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Diodex-20 Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol along with Diodex-20 Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Tell your doctor before taking Diodex-20 Tablet if you have asthma, water retention (oedema) or high blood pressure, stuff/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
PiroxicamCidofovir
Critical

Drug-Drug Interactions

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PiroxicamKetorolac tromethamine
Critical
How does the drug interact with Diodex-20 Tablet:
Using ketorolac tromethamine together with Diodex-20 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Diodex-20 Tablet with Ketorolac tromethamine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Consult a doctor if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without talking to a doctor.
PiroxicamCidofovir
Critical
How does the drug interact with Diodex-20 Tablet:
Co-administration of Cidofovir with Diodex-20 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Diodex-20 Tablet with Cidofovir is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamAdefovir dipivoxil
Severe
How does the drug interact with Diodex-20 Tablet:
Coadministration of Diodex-20 Tablet with Adefovir dipivoxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Diodex-20 Tablet with Adefovir dipivoxil together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamEverolimus
Severe
How does the drug interact with Diodex-20 Tablet:
Taking Everolimus and Diodex-20 Tablet together can increase the risk of kidney problems.

How to manage the interaction:
Although taking Everolimus and Diodex-20 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamValdecoxib
Severe
How does the drug interact with Diodex-20 Tablet:
Coadministration of Diodex-20 Tablet with Valdecoxib can increase the risk of side effects including inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Diodex-20 Tablet with Valdecoxib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medication without consulting a doctor.
PiroxicamFenoprofen
Severe
How does the drug interact with Diodex-20 Tablet:
Coadministration of Diodex-20 Tablet with Fenoprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Diodex-20 Tablet with Fenoprofen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
PiroxicamIndometacin
Severe
How does the drug interact with Diodex-20 Tablet:
Use of Indometacin with Diodex-20 Tablet can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Taking Indometacin with Diodex-20 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
PiroxicamAcalabrutinib
Severe
How does the drug interact with Diodex-20 Tablet:
Using acalabrutinib together with Diodex-20 Tablet may increase the risk of bleeding.

How to manage the interaction:
Although taking Diodex-20 Tablet and Acalabrutinib together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not discontinue any medications without consulting a doctor.
PiroxicamDasatinib
Severe
How does the drug interact with Diodex-20 Tablet:
Using Dasatinib together with Diodex-20 Tablet may increase the risk of bleeding.

How to manage the interaction:
Taking Diodex-20 Tablet with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you experience bruising, feeling dizzy or lightheaded, dark or bloody stools, headaches, contact a doctor right away. Do not stop using any medications without talking to a doctor.
PiroxicamIbuprofen
Severe
How does the drug interact with Diodex-20 Tablet:
Use of Diodex-20 Tablet with Ibuprofen can increase the risk of side effects such as inflammation(swelling with redness and pain), bleeding, ulceration.

How to manage the interaction:
Co-administration of Diodex-20 Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Diodex-20 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Diodex-20 Tablet works by blocking the effect of chemical messengers (prostaglandin), thereby reducing joint pain, stiffness, swelling, and inflammation.

Diarrhoea might be a side-effect of Diodex-20 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Diodex-20 Tablet for longer durations or high doses as it may cause unpleasant side effects. Do not exceed the dose and duration prescribed by your doctor.

Diodex-20 Tablet may increase the risk of heart attack or stroke. Do not use Diodex-20 Tablet immediately before or after bypass surgery. Inform your doctor if you have heart problems.

Consult your doctor before taking Diodex-20 Tablet if you have diabetes as Diodex-20 Tablet might increase the blood sugar levels.

Drug-Drug Interactions Checker List

  • DULOXETINE
  • SERTRALINE
  • METOPROLOL
  • CELECOXIB

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons might include a past injury such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.

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