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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer

Wockhardt Ltd

Consume Type

ORAL

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Not Returnable

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About Diuten M 5mg/1000mg Tablet ER

Diuten M 5mg/1000mg Tablet ER belongs to the class of 'antidiabetic drugs', primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Diuten M 5mg/1000mg Tablet ER also lowers the risk of heart failure in type 2 diabetic patients with heart diseases. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. Diuten M 5mg/1000mg Tablet ER is not indicated for use in type 1 diabetes.

Diuten M 5mg/1000mg Tablet ER is composed of two antidiabetic medicines, namely: Metformin and Dapagliflozin. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine.

Take Diuten M 5mg/1000mg Tablet ER as advised by your doctor. Some common side effects of Diuten M 5mg/1000mg Tablet ER include nausea, vomiting, diarrhoea, headache, weakness, runny nose, genital infection, dizziness, taste changes, and sore throat. Sometimes, Diuten M 5mg/1000mg Tablet ER can cause side effects like lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation) and diabetic ketoacidosis (excess production of blood acids (ketones)). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Diuten M 5mg/1000mg Tablet ER may cause hypoglycaemia (low blood sugar); hence it advised to take healthy food with enough calories and avoid heavy exercises. Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Diuten M 5mg/1000mg Tablet ER, let your doctor know if you have any medical history of heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, low blood pressure, and yeast infection of genitals. It is advised to avoid your alcohol intake while using Diuten M 5mg/1000mg Tablet ER to decrease the risk of lactic acidosis. Diuten M 5mg/1000mg Tablet ER is not recommended for use during the second or third trimester of pregnancy and breastfeeding.

Uses of Diuten M 5mg/1000mg Tablet ER

Type 2 Diabetes mellitus.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it. Take it preferably with a meal since it lowers blood sugar levels and may cause gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

Diuten M 5mg/1000mg Tablet ER treats type 2 diabetes mellitus and contains Metformin and Dapagliflozin. Metformin is a biguanide and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. Diuten M 5mg/1000mg Tablet ER also reduces the risk of heart failure in patients with type 2 diabetes and heart disease. Diuten M 5mg/1000mg Tablet ER may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Diuten M 5mg/1000mg Tablet ER

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Weakness
  • Runny nose
  • Genital infection
  • Dizziness
  • Taste changes
  • Sore throat
  • Lactic acidosis (build-up of lactic acid in the bloodstream) (rare)
  • Diabetic ketoacidosis (a diabetic complication with excess blood acids) (rare)

Drug Warnings

Inform your doctor if you take other antidiabetic drugs so that the dosage of Diuten M 5mg/1000mg Tablet ER will be adjusted accordingly. Do not abruptly stop taking Diuten M 5mg/1000mg Tablet ER midway if the doctor did not advise you. Diuten M 5mg/1000mg Tablet ER may cause hypoglycaemia (low blood sugar); hence it is advised to make healthy food with enough calories and avoid heavy exercises. Brief your medical history to doctor if you have any heart, kidney or liver diseases, breathing problems (asthma, obstructive lung diseases), blood problems like anaemia (lack of blood cells), vitamin B12 deficiency, pancreas problems/surgery, dehydration, alcohol use, low blood pressure, and yeast infection of genitals before taking Diuten M 5mg/1000mg Tablet ER. Avoid alcohol intake while using Diuten M 5mg/1000mg Tablet ER since it may increase the risk of lactic acidosis. Diuten M 5mg/1000mg Tablet ER is not recommended for use during the second or third trimester of pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Diuten M 5mg/1000mg Tablet ER is not recommended for people younger than 18 years of age.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Diuten M 5mg/1000mg Tablet ER for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Diuten M 5mg/1000mg Tablet ER.
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas. 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Author Details

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FAQs

Diuten M 5mg/1000mg Tablet ER contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

Diuten M 5mg/1000mg Tablet ER may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Diuten M 5mg/1000mg Tablet ER with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.

Your doctor may advise Diuten M 5mg/1000mg Tablet ER with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Diuten M 5mg/1000mg Tablet ER with or without other antidiabetic drugs.

Diuten M 5mg/1000mg Tablet ER should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. Diuten M 5mg/1000mg Tablet ER is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

While using Diuten M 5mg/1000mg Tablet ER, if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.

Drug-Drug Interactions Checker List

  • HYDROCHLOROTHIAZIDE
  • IBUPROFEN
  • CELECOXIB
  • CIMETIDINE

Special Advise

  • It is advised to monitor your blood sugar levels regularly.
  • If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Diuten M 5mg/1000mg Tablet ER temporarily.
  • Regular monitoring of kidney functioning is advised while using Diuten M 5mg/1000mg Tablet ER.
  • Diuten M 5mg/1000mg Tablet ER may make you test positive for a urine glucose test, hence inform your doctor in advance that you take Diuten M 5mg/1000mg Tablet ER. 

Disease/Condition Glossary

Diabetes mellitus, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots. 

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