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  3. Divaa-500 Tablet 15's

Divaa-500 Tablet 15's, Pack of 15 TABLETS
Divaa-500 Tablet 15's, Pack of 15 TABLETS
Divaa-500 Tablet 15's, Pack of 15 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

DIVALPROEX SODIUM-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Divaa-500 Tablet

Divaa-500 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Divaa-500 Tablet is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Divaa-500 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity. Thereby helps in controlling seizures. Divaa-500 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

Take Divaa-500 Tablet with or without food. You are advised to take Divaa-500 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Please do not stop taking Divaa-500 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Divaa-500 Tablet if you are pregnant as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Divaa-500 Tablet . Consult your doctor before taking Divaa-500 Tablet if you are breastfeeding. Avoid driving or operating machinery as Divaa-500 Tablet causes dizziness, and may affect thinking and motor skills. Avoid consuming alcohol along with Divaa-500 Tablet as it could lead to increased dizziness. Care should be taken while giving Divaa-500 Tablet to children below 2years as there is a higher risk of liver intoxication during the first 6months of treatment. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Divaa-500 Tablet

Epilepsy, bipolar disorder, migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Sprinkle capsule: Swallow it as a whole with water or sprinkle the capsule contents on food and consume.

Medicinal Benefits

Divaa-500 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Divaa-500 Tablet is used to treat epilepsy/seizures/fits. Additionally, Divaa-500 Tablet is also used to treat mood disorder and to prevent migraine headaches. Divaa-500 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Divaa-500 Tablet treats mood disorder by increasing the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Divaa-500 Tablet prevents migraine headache by limiting the transmission of nerve pain. Divaa-500 Tablet is used alone or in combination to treat simple seizures, complex partial seizures and complex absence seizures. Divaa-500 Tablet is used in combination to treat multiple seizures such as absence seizures.

Storage

Keep Divaa-500 Tablet out of reach and sight of children.

Drug Warnings

Do not take Divaa-500 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Divaa-500 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendency while taking Divaa-500 Tablet . Divaa-500 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Divaa-500 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Divaa-500 Tablet if you are pregnant as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Divaa-500 Tablet . Consult your doctor before taking Divaa-500 Tablet if you are breastfeeding. Avoid driving or operating machinery as Divaa-500 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Divaa-500 Tablet as it could lead to increased dizziness. Care should be taken while giving Divaa-500 Tablet to children below 2years as there is a higher risk of liver intoxication during the first 6months of treatment.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
DivalproexMeropenem
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Divaa-500 Tablet:
Coadministration of Glycerol phenylbutyrate and Divaa-500 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Divaa-500 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexMeropenem
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and Meropenem can reduce the blood levels of Divaa-500 Tablet sodium.

How to manage the interaction:
Co-administration of Divaa-500 Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexSodium oxybate
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Sodium oxybate and Divaa-500 Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Divaa-500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexEsketamine
Severe
How does the drug interact with Divaa-500 Tablet:
Coadministration of Esketamine and Divaa-500 Tablet can increase the side effects of esketamine.

How to manage the interaction:
Although taking Divaa-500 Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
DivalproexKetamine
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Divaa-500 Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexLeflunomide
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Divaa-500 Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexBexarotene
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Divaa-500 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexTeriflunomide
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaa-500 Tablet and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexDoripenem
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and Doripenem can reduce the blood levels of Divaa-500 Tablet sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Divaa-500 Tablet with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
DivalproexMipomersen
Severe
How does the drug interact with Divaa-500 Tablet:
Co-administration of Divaa-500 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaa-500 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, help those around you know what to do.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Side Effects of Divaa-500 Tablet

  • Abdominal pain
  • Back pain
  • Constipation
  • Diarrhoea
  • Dizziness
  • Nausea
  • Increased appetite
  • Vomiting
  • Vision problems
  • Weight changes
  • Problems with walking or coordination

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Divaa-500 Tablet Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Divaa-500 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Divaa-500 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Divaa-500 Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Divaa-500 Tablet without consulting your doctor. To treat your condition effectually continue taking Divaa-500 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Divaa-500 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Divaa-500 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Divaa-500 Tablet . Avoid getting pregnant while taking Divaa-500 Tablet as it could lead to serious birth defects. Do not stop taking Divaa-500 Tablet and consult your doctor immediately if you become pregnant.

Divaa-500 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Divaa-500 Tablet .

Topiramate (anticonvulsant) should not be taken along with Divaa-500 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PREGABALIN
  • TOPIRAMATE
  • PHENOBARBITAL
  • PRIMIDONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ETHOSUXIMIDE
  • ZIDOVUDINE
  • DULOXETINE
  • ESCITALOPRAM
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • ALPRAZOLAM
  • RIFAMPICIN
  • WARFARIN
  • IMIPENEM
  • MEROPENEM
  • DIAZEPAM

Special Advise

  • Regular monitoring of blood count and coagulation tests are advised while taking Divaa-500 Tablet as it may cause thrombocytopenia (low platelet levels).
  • Divaa-500 Tablet may cause liver toxicity, usually during the first 6months of treatment. Children below two years are at a higher risk. Regular monitoring of liver function tests before treatment and at frequent intervals is advised.
  • Divaa-500 Tablet might alter thyroid function tests and urine ketone tests. Inform the person doing the tests that you are taking Divaa-500 Tablet .

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalised and partial seizures. Generalised seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows.

Migraine: Migraine is a neurological condition which is characterized by intense headaches. Symptoms include nausea, vomiting, and sensitivity to light and sound.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Divaa-500 Tablet as it may cause increased dizziness.

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Pregnancy

Unsafe

Divaa-500 Tablet belongs to pregnancy category D. Avoid taking Divaa-500 Tablet if you are pregnant as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Divaa-500 Tablet may pass into breastmilk. Consult your doctor before taking Divaa-500 Tablet if you are breastfeeding.

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Driving

Unsafe

Divaa-500 Tablet causes dizziness and may affect thinking and motor skills. Do not drive or operate machinery.

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Liver

Unsafe

Divaa-500 Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Divaa-500 Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight. Care should be taken in children below 2years as they are at a higher risk of liver toxicity.

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