Divaril-XR-500mg Tablet 10's

₹120

(Inclusive of all Taxes)

₹18.0 Cashback (15%)

Written By Urvashi Bharti , MBBS

Reviewed By Sunny S , MBBS

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Prescription drug

Whats That

About Divaril-XR-500mg Tablet

Divaril-XR-500mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. In addition, Divaril-XR-500mg Tablet also treats manic episodes associated with bipolar disorder. Besides this, it can also prevent migraine symptoms (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state.

Divaril-XR-500mg Tablet contains Valproic acid, which reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Divaril-XR-500mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Divaril-XR-500mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Divaril-XR-500mg Tablet should be taken as prescribed by the doctor. You may sometimes experience nausea, upset stomach or stomach pain, tremors (shakes), sleepiness, headache, weight gain and thinning hair. Most of these side effects are temporary and will go away on their own. However, if you suffer these adverse effects on a regular basis, you should consult your doctor.

Inform your doctor if you are allergic to any components present in Divaril-XR-500mg Tablet . If you are pregnant, do not take Divaril-XR-500mg Tablet because it may cause serious congenital defects. Use effective contraception if you are of childbearing age while taking Divaril-XR-500mg Tablet . If you are breastfeeding, inform your doctor before taking Divaril-XR-500mg Tablet . As Divaril-XR-500mg Tablet causes sleepiness and dizziness, do not drive or operate machinery. Avoid drinking alcohol with Divaril-XR-500mg Tablet as it may cause dizziness and tiredness. To rule out any negative effects, keep your doctor updated about your health condition and medications.

Uses of Divaril-XR-500mg Tablet

Epilepsy (fits), Bipolar disorder, Migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Divaril-XR-500mg Tablet contains Valproic acid, an anticonvulsant (or anti-epileptic) medicine that reduces the brain's excessive and aberrant nerve activity. As a result, it aids in the control of seizures. Divaril-XR-500mg Tablet raises the concentration of a chemical molecule known as GABA, which helps to stop nerve communication across the brain and has a calming effect. This contributes to the treatment of bipolar disorder. Divaril-XR-500mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches.

Storage

Keep Divaril-XR-500mg Tablet out of the sight and reach of children.

Side effects of Divaril-XR-500mg Tablet

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Loss Of Memory

Write things in a notebook or on sticky notes.
Be physically and mentally active.
Maintain social interaction to avoid stress and depression which could contribute to memory loss.
Sleep well as inadequate sleep may also cause memory loss.
Maintain a healthy diet which includes fruits, vegetables, whole grains, fish and skinless poultry.
Avoid alcohol consumption as it may cause confusion and memory loss.

Inflammation Of Air Passages In Lungs

Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:

If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
Regularly track your symptoms and report any changes or concerns to your healthcare provider.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Depression

Managing depression as a side effect of medication: a comprehensive guide.

Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
Tell your doctor about your depression symptoms to adjust medication.
Consult a therapist or counsel for emotional support.
Engage in regular exercise to release endorphins (neurotransmitters).
Practice stress-reducing techniques like meditation and deep breathing.
Build a support network of friends, family, and support groups.
Establish a consistent sleep schedule.
Eat a nutritious diet rich in fruits, vegetables, and whole grains.
Limit or avoid alcohol and recreational substances.
Keep a mood journal to track symptoms and progress.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Before taking the Divaril-XR-500mg Tablet , let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, suspect you are pregnant, plan to have a baby, or are breastfeeding. You should not become pregnant while you are receiving Divaril-XR-500mg Tablet . Consult your doctor immediately if you become pregnant while receiving a Divaril-XR-500mg Tablet . Alcohol should be avoided during treatment with this medicine. You must not drive or operate machinery while receiving Divaril-XR-500mg Tablet .

Drug-Drug Interactions

DivalproexGlycerol phenylbutyrate

Critical

DivalproexSodium phenylbutyrate

Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate

Critical

How does the drug interact with Divaril-XR-500mg Tablet:
Coadministration of Glycerol phenylbutyrate and Divaril-XR-500mg Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Divaril-XR-500mg Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

DivalproexSodium phenylbutyrate

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Sodium phenylbutyrate and Divaril-XR-500mg Tablet can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Divaril-XR-500mg Tablet with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.

DivalproexVorinostat

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Coadministration of Divaril-XR-500mg Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Divaril-XR-500mg Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.

DivalproexBuprenorphine

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of buprenorphine with Divaril-XR-500mg Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Divaril-XR-500mg Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

DivalproexMipomersen

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Divaril-XR-500mg Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaril-XR-500mg Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.

DivalproexTeriflunomide

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Divaril-XR-500mg Tablet and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaril-XR-500mg Tablet and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DivalproexSodium oxybate

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Sodium oxybate and Divaril-XR-500mg Tablet can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Sodium oxybate and Divaril-XR-500mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, sweating, palpitations, and shortness of breath, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

DivalproexLomitapide

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Divaril-XR-500mg Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Divaril-XR-500mg Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.

DivalproexLamotrigine

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Coadministration of Divaril-XR-500mg Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divaril-XR-500mg Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.

DivalproexKetamine

Severe

How does the drug interact with Divaril-XR-500mg Tablet:
Co-administration of Divaril-XR-500mg Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Divaril-XR-500mg Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Adolescents and adults are advised to follow the Atkins diet (high fat, low carbohydrate).
Exercising on a regular basis aids with weight maintenance and general health.
Rest well, and get plenty of sleep.
Avoid smoking and drinking alcohol.
Meditation and yoga can help reduce stress, reduce pain sensitivity, and increase coping abilities.
Have a seizure response plan in place, and make sure everyone around you knows what to do in the event of a seizure.
Prepare your living environment; simple changes may help reduce the risk of physical damage during a seizure.
Understand what causes seizures and try to reduce or avoid them.
Please keep your overall health in mind, as it can aid in the reduction of seizure activity.
Install an alarm or an emergency gadget to summon help during a seizure attack.

Side Effects of Divaril-XR-500mg Tablet

Stomach pain
Feeling or being sick
Diarrhoea
Dry or sore mouth or swollen gums
Shakes (tremors) in a part of your body
Unusual eye movements
Feeling tired or sleepy
Headache
Weight gain
Thinning hair, or changes to the colour or texture of your hair
Irregular or delayed periods

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Author Details

Written By

Urvashi Bharti

MBBS

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:35 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Divaril-XR-500mg Tablet help to control seizures?

Divaril-XR-500mg Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helping in controlling seizures.

Is Divaril-XR-500mg Tablet used to treat bipolar disorder?

Divaril-XR-500mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Does Divaril-XR-500mg Tablet help in preventing migraine?

Divaril-XR-500mg Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraine is a neurological condition which is characterized by intense headaches.

Does Divaril-XR-500mg Tablet cause weight gain?

Divaril-XR-500mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

I am planning for pregnancy. Is it safe to take Divaril-XR-500mg Tablet ?

Use an effective method of contraception during the treatment with Divaril-XR-500mg Tablet . Avoid getting pregnant while taking Divaril-XR-500mg Tablet as it could lead to serious birth defects. Do not stop taking Divaril-XR-500mg Tablet and consult your doctor immediately if you become pregnant.

Does prolonged intake of Divaril-XR-500mg Tablet causes weight gain?

Divaril-XR-500mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Drug-Drug Interactions Checker List

CARBAMAZEPINE
WARFARIN
ASPIRIN
CIMETIDINE
RITONAVIR
ERYTHROMYCIN
VENLAFAXINE
QUETIAPINE
CHOLESTYRAMINE
MEFLOQUINE
CHLOROQUINE

Special Advise

Blood and urine tests may be affected by the Divaril-XR-500mg Tablet . Inform the person conducting the exams that you will be taking Divaril-XR-500mg Tablet .
If you are of childbearing age, utilise effective contraception continuously during your treatment with Divaril-XR-500mg Tablet .
Contact your doctor immediately if you become pregnant while taking Divaril-XR-500mg Tablet .

Disease/Condition Glossary

Epilepsy: It is a sudden rush of electricity in the brain. It is a nervous system disorder that occurs due to disturbed nerve cell activity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle cramps and spasms. More substantial seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.

Migraine: Migraine is a neurological condition that is characterized by intense headaches. A migraine is usually a moderate or severe headache felt as a throbbing pain on one side of the head.