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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition

DIGOXIN-50MCG/ML

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Dixin Pead Solution 60 ml

Dixin Pead Solution 60 ml belongs to a group of medicines called cardiac glycosides used to treat irregular heartbeats and manage the symptoms of heart failure. Heart failure is a chronic condition in which the heart is unable to pump blood as effectively as it should. Irregular heartbeat is a condition in which your heart beats irregularly, too fast or too slow.

Dixin Pead Solution 60 ml contains digoxin, i.e. cardiac glycosides that help to increase the output force of the heart and reduces the rate of heart contractions. Dixin Pead Solution 60 ml works on the heart muscle directly and increases the force with which heart muscle contracts with each heartbeat. Thereby, it makes heart efficient in pumping blood around the body and slows down the rate at which heartbeats.

Take Dixin Pead Solution 60 ml as prescribed. Your doctor will recommend you how often you take Dixin Pead Solution 60 ml based on your medical condition. Some people may experience common side effects like diarrhoea, nausea, vomiting, dizziness, abnormal heartbeat or skin rash. Most of these side effects of Dixin Pead Solution 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are known to be allergic to Dixin Pead Solution 60 ml or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Regular blood tests are recommended by your doctor while taking Dixin Pead Solution 60 ml to monitor the amount of Dixin Pead Solution 60 ml in the bloodstream as its toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused due to vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food) or any lung or kidney disease, please inform your doctor before taking Dixin Pead Solution 60 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin Pead Solution 60 ml has a very narrow therapeutic index. It means small differences in dose of drugs in the body may lead to life-threatening conditions or serious side effects. This makes its use limited and requires close monitoring by doctors like regular electrocardiogram (ECG). So, try not to self-medicate and suggest Dixin Pead Solution 60 ml to others.

Uses of Dixin Pead Solution 60 ml

Irregular heartbeats, Prevention of heart failure

Directions for Use

Tablet: Take it with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.Paediatric solution: Shake the bottle well before use. Check the label for directions and give it with or without food in doses as prescribed by a doctor with the help of a dosing syringe.

Medicinal Benefits

Dixin Pead Solution 60 ml is a cardiac glycoside that is used to treat heart failure and irregular heartbeats. Dixin Pead Solution 60 ml increases the force with which heart muscle contracts with each heartbeat and makes heart efficient in pumping blood around the body. Thus, slows down the rate at which heartbeats and makes heart rate normal. Dixin Pead Solution 60 ml improves heart failure symptoms such as exercise capacity and reduces the number of hospitalizations.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dixin Pead Solution 60 ml

  • Feeling confused
  • Dizziness
  • Nausea or vomiting
  • Loss of appetite
  • Diarrhoea
  • Changes in your vision (including blurred vision and not able to look at bright light)

Drug Warnings

If you are known to be allergic to Dixin Pead Solution 60 ml or any other medicines, please tell your doctor. Pregnant or breastfeeding women are advised to consult a doctor before taking the tablet. Avoid intake of alcohol with Dixin Pead Solution 60 ml as it may increase the risk of drowsiness. Dixin Pead Solution 60 ml may cause vision problems in some people. Make sure you are not affected before driving. Regular blood tests are recommended by your doctor while taking Dixin Pead Solution 60 ml to monitor the amount of digoxin in blood as digoxin toxicity can lead to several forms of heart rhythm disturbances, vomiting, nausea and visual disturbances. If you have beriberi disease caused by vitamin B1 deficiency, malabsorption syndrome (unable to absorb minerals from food), thyroid, or any lung or kidney disease, please inform your doctor before taking Dixin Pead Solution 60 ml so that the dose may be adjusted or an alternate medicine may be prescribed accordingly. Dixin Pead Solution 60 ml has a narrow therapeutic index which makes its use limited and requires close monitoring as small change in dose or blood concentration may lead to severe adverse effects, and overdose may lead to life-threatening reactions.

Drug-Drug Interactions

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DigoxinDolasetron
Severe
DigoxinCalcium gluconate
Severe

Drug-Drug Interactions

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DigoxinDolasetron
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Dixin Pead Solution 60 ml with Dolasetron can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Dixin Pead Solution 60 ml with Dolasetron can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these risk factors or if you experience symptoms like an irregular heartbeat, dizziness, fainting, or a fast or irregular heartbeat, it is important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DigoxinCalcium gluconate
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Calcium gluconate with Dixin Pead Solution 60 ml may affect heart rhythm.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Dixin Pead Solution 60 ml if prescribed by the doctor. Consult the prescriber if you experience symptoms of irregular heartbeat, blurred vision, chest tightness, nausea, and seizures. Do not discontinue the medication without consulting a doctor.
DigoxinGlycopyrronium bromide
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Dixin Pead Solution 60 ml and Glycopyrronium bromide may increase the serum concentration of Dixin Pead Solution 60 ml and increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dixin Pead Solution 60 ml and Glycopyrronium bromide, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, confusion, loss of appetite, nausea, vomiting, diarrhea, change in vision such as blurry or yellow vision, fatigue, and fast or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DigoxinSaquinavir
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Dixin Pead Solution 60 ml and Saquinavir may increase the risk of severe irregular heart rhythm.

How to manage the interaction:
If you are supposed to take Dixin Pead Solution 60 ml and Saquinavir together, a doctor may adjust the dose or monitor more frequently to safely use both medications. However, if you develop lightheadedness, fainting, sudden dizziness, nausea, vomiting, loss of appetite, slow pulse, vision disturbances, or irregular heartbeat during treatment with these medications. Contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
DigoxinFingolimod
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Fingolimod with Dixin Pead Solution 60 ml may increase the risk or severity of slowing down of the heart rate.

How to manage the interaction:
Although there is a possible interaction between Dixin Pead Solution 60 ml and Fingolimod, you can take these medicines together if prescribed by a doctor. It's important to monitor your heart rate and talk to a doctor about any alternative medications that don't interact. If you experience any symptoms like chest pain, shortness of breath, or fainting, it's important to call your doctor right away. Do not discontinue any medications without consulting a doctor.
DigoxinFamotidine
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Dixin Pead Solution 60 ml and Famotidine may increase the level or effect of Dixin Pead Solution 60 ml.

How to manage the interaction:
Although there is a possible interaction between Dixin Pead Solution 60 ml and Famotidine, you can take these medicines together if prescribed by a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinSucralfate
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Sucralfate together with Dixin Pead Solution 60 ml may decrease the effects of Dixin Pead Solution 60 ml.

How to manage the interaction:
If you are supposed to take Dixin Pead Solution 60 ml and Sucralfate together, your doctor may adjust the dose to safely use both medications. Do not discontinue the medication without consulting a doctor.
DigoxinClarithromycin
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Clarithromycin with Dixin Pead Solution 60 ml may increase the blood levels and effects of Dixin Pead Solution 60 ml.

How to manage the interaction:
Although there is a possible interaction, Clarithromycin can be taken with Dixin Pead Solution 60 ml if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of excessive Dixin Pead Solution 60 ml levels such as diarrhea, nausea, loss of appetite, vomiting, visual disturbances, and an abnormally fast or slow or uneven heartbeat. Do not discontinue the medication without consulting a doctor.
DigoxinNadolol
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Co-administration of Dixin Pead Solution 60 ml and Nadolol may slow down the heart rate and lead to increased side effects.

How to manage the interaction:
If you are supposed to take Dixin Pead Solution 60 ml and Nadolol together, a doctor may adjust the dose to safely use both medications. However, if you experience decreased appetite, nausea, vomiting, confusion, diarrhea, seizures, visual changes, overtiredness, irregular heartbeats, and abnormally fast or slow heartbeats, contact a doctor. Do not discontinue the medication without consulting a doctor.
DigoxinAtazanavir
Severe
How does the drug interact with Dixin Pead Solution 60 ml:
Coadministration of Dixin Pead Solution 60 ml and Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Dixin Pead Solution 60 ml and Atazanavir, you can take these medicines together if prescribed by a doctor. However, if you develop fainting, lightheadedness, sudden dizziness, or irregular heartbeat, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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DIGOXIN-50MCGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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DIGOXIN-50MCGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Dixin Pead Solution 60 ml with Grapefruit and Grapefruit juice may increase the side effects of Dixin Pead Solution 60 ml. Consuming Grapefruit and grapefruit juice should be avoided while taking Dixin Pead Solution 60 ml.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do the regular exercise as it helps to lower blood pressure and keeps blood vessels and heart in good condition.
  • Quit smoking as smoking increases blood pressure and heart rate.
  • Eat balanced and healthy diet which includes plenty of vegetables, fruits, low fat or fat free products.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Author Details

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Drug-Diseases Interactions

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DIGOXIN-50MCGOther conduction disorders
Severe
DIGOXIN-50MCGAbnormalities of heart beat
Severe

Drug-Diseases Interactions

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DIGOXIN-50MCGOther conduction disorders
Severe
How does the disease interact with Dixin Pead Solution 60 ml:
In cases like the Wolff-Parkinson-White syndrome, Dixin Pead Solution 60 ml may improve accessory route conduction.

How to manage the interaction:
Dixin Pead Solution 60 ml should be used with caution in patients with Wolff-Parkinson-White syndrome (a heart condition that causes rapid heartbeat).
DIGOXIN-50MCGAbnormalities of heart beat
Severe
How does the disease interact with Dixin Pead Solution 60 ml:
Dixin Pead Solution 60 ml prolongs the PR interval by slowing sinoatrial and AV conduction. Dixin Pead Solution 60 ml therapy can cause severe sinus bradycardia or sinoatrial block in people with preexisting sinus node dysfunction, and it can cause progressive or full heart block in patients with incomplete AV block.

How to manage the interaction:
Dixin Pead Solution 60 ml may be administered to patients with complete, stable AV block (an electrical signal that controls your heartbeat is partially or completely blocked) who have congestive heart failure, provided the block was not induced by cardiac glycosides.
DIGOXIN-50MCGDisorders of mineral metabolism
Severe
How does the disease interact with Dixin Pead Solution 60 ml:
Dixin Pead Solution 60 ml and calcium have cumulative effects on inotropy. As a result, Dixin Pead Solution 60 ml toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Dixin Pead Solution 60 ml, and serum calcium levels should be monitored during therapy.
DIGOXIN-50MCGDisorders of mineral metabolism
Severe
How does the disease interact with Dixin Pead Solution 60 ml:
Dixin Pead Solution 60 ml and calcium have cumulative effects on inotropy. As a result, Dixin Pead Solution 60 ml toxicity and dangerous arrhythmias are predisposed in patients with hypercalcemia from any source.

How to manage the interaction:
Hypercalcemia (too much calcium in the blood) should be corrected before starting treatment with Dixin Pead Solution 60 ml, and serum calcium levels should be monitored during therapy.
DIGOXIN-50MCGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Dixin Pead Solution 60 ml:
Dixin Pead Solution 60 ml makes the myocardium more sensitive when potassium and/or magnesium are depleted. Despite Dixin Pead Solution 60 ml serum drug concentrations, Dixin Pead Solution 60 ml toxicity may happen in patients with hypokalemia or hypomagnesemia.

How to manage the interaction:
Dixin Pead Solution 60 ml should be used with caution in patients with or who are at risk of developing potassium and/or magnesium deficiency, including patients on diuretic therapy; those with primary or secondary aldosteronism (may have low potassium levels), severe or prolonged diarrhoea or vomiting, malnutrition; and renal dialysis patients. Electrolyte imbalances may be corrected before starting the treatment.
DIGOXIN-50MCGThyrotoxicosis [hyperthyroidism]
Moderate
How does the disease interact with Dixin Pead Solution 60 ml:
Treatment of the underlying illness is the best way to control heart failure and/or atrial arrhythmias brought on by hypermetabolic or hyperdynamic conditions such hyperthyroidism, hypoxia, or arteriovenous shunt.

How to manage the interaction:
Dixin Pead Solution 60 ml should be used with caution in patients with hyperthyroidism. Your doctor may adjust the dose secondary to changes in the thyroid condition.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • QUINIDINE
  • ATAZANAVIR
  • SAQUINAVIR
  • CLARITHROMYCIN
  • ITRACONAZOLE
  • ADENOSINE
  • DOLASETRON
  • ARBUTAMINE
  • CERITINIB
  • LAPATINIB
  • FINGOLIMOD
  • FLIBANSERIN
  • CALCIUM CHLORIDE
  • CALCIUM GLUCEPTATE
  • CALCIUM GLUCONATE

Special Advise

  • Regular blood tests are advised while taking Dixin Pead Solution 60 ml to monitor digoxin levels in the blood, potassium levels and kidney functioning.
  • Low salt diet and regular exercise are recommended along with Dixin Pead Solution 60 ml for effective results.
  • Regular electrocardiogram (ECG) should be done to see the effect of Dixin Pead Solution 60 ml on your heartbeat.

Disease/Condition Glossary

Heart failure: It is a chronic condition in which the heart is unable to pump blood as effectively as it should. Heart failure may occur due to certain conditions like high blood pressure, swelling or damage of heart muscle, faulty heart valves or narrow arteries in the heart. Symptoms of heart failure include shortness of breath, tiredness, fast heartbeat and swollen legs.

Arrhythmia (irregular heartbeat) is a condition in which your heart beats irregularly, too fast or too slow. Symptoms of irregular heartbeat include chest pain, shortness of breath, fast or slow heartbeat. 60 to 100 beats per minute is generally considered as normal heart rate.

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