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Reviewed By Sunny S , MBBS
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ORAL

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Not Returnable

Expires on or after

Apr-24

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About Dolocold Syrup 60 ml

Dolocold Syrup 60 ml belongs to a class of medication called 'cough and cold medications' primarily used to treat the common cold and allergic symptoms like sneezing watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.

Dolocold Syrup 60 ml is composed of four medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant).  Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing the stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Dolocold Syrup 60 ml.

Take Dolocold Syrup 60 ml as prescribed. Your doctor will recommend how often you take Dolocold Syrup 60 ml based on your medical condition. Do not crush, chew, or break it. Your doctor will recommend how often you take Dolocold Syrup 60 ml based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, difficulty in sleeping, headache. Everyone doesn't need to experience the above side effects. In some cases, Dolocold Syrup 60 ml may cause a severe allergic skin reaction, probably due to paracetamol, which may disappear in some time.

Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Dolocold Syrup 60 ml. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Dolocold Syrup 60 ml as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Dolocold Syrup 60 ml if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Intake of more than 4 gm of paracetamol can damage your liver, so it is better to avoid the use of Dolocold Syrup 60 ml in severe liver damage. Cetirizine present in the Dolocold Syrup 60 ml can make you sleepy, so do not drive or operate heavy machinery after taking Dolocold Syrup 60 ml. Phenylephrine present in Dolocold Syrup 60 ml should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). 

Uses of Dolocold Syrup 60 ml

Common cold, Allergies

Directions for Use

Take Dolocold Syrup 60 ml with food or as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, break or chew it.

Medicinal Benefits

Dolocold Syrup 60 ml is primarily used to treat common cold symptoms and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It is composed of four medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Dolocold Syrup 60 ml. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dolocold Syrup 60 ml

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty falling or staying asleep)
  • Allergic reactions

Drug Warnings

If you are allergic to Dolocold Syrup 60 ml or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Dolocold Syrup 60 ml. Do not use Dolocold Syrup 60 ml in breastfeeding mothers without a doctor’s advice as it contains caffeine, which may be excreted in breast milk and cause harm to the baby. Dolocold Syrup 60 ml is not recommended for children below 4 years. Please do not take more than the prescribed dose of Dolocold Syrup 60 ml as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, enlarged prostate gland,  kidney, liver, heart, or urinary problems, inform your doctor before taking Dolocold Syrup 60 ml. Do not take Dolocold Syrup 60 ml if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days. Also, avoid intake of chocolate, alcohol, and caffeine-containing beverages like coffee as they may increase the risk of severity of side effects. Do not take Dolocold Syrup 60 ml if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Cetirizine present in the Dolocold Syrup 60 ml can make you sleepy, so do not drive or operate heavy machinery after taking Dolocold Syrup 60 ml. Phenylephrine present in Dolocold Syrup 60 ml should be used with caution in patients with occlusive vascular disease (nerve/artery blockage) including Raynaud's phenomenon (decreased blood flow to the fingers). 

Drug-Drug Interactions

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PhenylephrineSevoflurane
Critical
PhenylephrineSelegiline
Critical

Drug-Drug Interactions

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PhenylephrineSevoflurane
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Co-administration of Dolocold Syrup 60 ml with Sevoflurane can increase the levels of Dolocold Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Dolocold Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Co-administration of Selegiline with Dolocold Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Dolocold Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Taking Tranylcypromine with Dolocold Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Dolocold Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Taking Furazolidone with Dolocold Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Dolocold Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Dolocold Syrup 60 ml only after 14 days of stopping Furazolidone.
PhenylephrinePropofol
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Taking Dolocold Syrup 60 ml with Propofol may lead to increased levels of Dolocold Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Dolocold Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Taking Dolocold Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Dolocold Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Dolocold Syrup 60 ml:
Taking Dolocold Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Dolocold Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Dolocold Syrup 60 ml:
Co-administration of Dolocold Syrup 60 ml and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Dolocold Syrup 60 ml and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Dolocold Syrup 60 ml:
Co-administration of Mipomersen with Dolocold Syrup 60 ml may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Dolocold Syrup 60 ml and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Dolocold Syrup 60 ml:
Co-administration of Lomitapide and Dolocold Syrup 60 ml may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Dolocold Syrup 60 ml and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria like yogurt to improve overall health.
  • Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Dolocold Syrup 60 ml as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • IMIPRAMINE
  • AMITRIPTYLINE
  • CLONAZEPAM
  • ALPRAZOLAM
  • DEXTROMETHORPHAN
  • ALBUTEROL
  • RAMELTEON
  • IBUPROFEN

Special Advise

  • Avoid alcohol consumption with Dolocold Syrup 60 ml as it may cause tiredness, drowsiness, or lack of concentration. 
  • Do not take Dolocold Syrup 60 ml if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
  • Please inform your doctor if you are pregnant or breastfeeding before starting Dolocold Syrup 60 ml as it contains caffeine, which can pass in the breast milk, which may have a stimulating effect on a breastfed child.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

Allergies: It occurs when foreign elements that cause allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.

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