Dolostat MR Tablet 10's
₹48.6*
MRP ₹54
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₹46*
MRP ₹54
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Dolostat MR Tablet 10's is a combination drug that belongs to NSAIDs (non-steroidal anti-inflammatory drugs) or pain killers primarily used for pain relief and muscle relaxation. Muscle pain (myalgia) is widespread and generally refers to uncomfortable sensations in the muscles which can be due to illness, injury or excessive exercise. It can be continuous or can also occur at intervals.
Dolostat MR Tablet 10's contains three medicines, namely: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever) and Chlorzoxazone (muscle relaxant). Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.
Dolostat MR Tablet 10's can be taken with or without food as advised by your doctor for the best results. Do not stop taking Dolostat MR Tablet 10's even if you feel better to avoid any unpleasant side effects. Common side effects of Dolostat MR Tablet 10's include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. If any of these side effects get worse or do not subside, please visit your doctor immediately.
Dolostat MR Tablet 10's should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Dolostat MR Tablet 10's as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.
Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.
Dolostat MR Tablet 10's should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Dolostat MR Tablet 10's as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.
Drug-Drug Interactions: Dolostat MR Tablet 10's interacts with sleeping pills (alprazolam, escitalopram, zolpidem), pain killers (tramadol, oxycodone, hydrocodone), antiepileptics or medicines for fits (gabapentin, topiramate, pregabalin), diuretics or water pills (fluoxetine), an antidepressant (duloxetine), antiallergic (diphenhydramine, cetirizine), muscle relaxant and antispasmodic (baclofen).
Drug-Food Interactions: St. John's wort (a herbal supplement) used as an antidepressant can interact with Dolostat MR Tablet 10's and cause dizziness, so its usage should be avoided with Dolostat MR Tablet 10's.
Drug-Disease Interactions: People with alcoholism, liver disease, kidney disease, stomach ulcer/bleeding, and intestinal ulcer/bleeding should avoid using Dolostat MR Tablet 10's.
Musculoskeletal pain: It is a pain of bones, muscles, the tissues connecting to muscle-muscle and bone-muscle (cartilage, tendon) and nerves which can be felt just in one area of the body, like low back pain. This type of pain can be felt throughout the body if widespread as in the case of fibromyalgia. The musculoskeletal pain can range from mild/moderate to severe enough, which is sufficient to interfere with your daily routine. It can short-lived (acute) as well as can continue for more than 3-6 months (chronic). The most common musculoskeletal pain includes muscle pain (myalgia) from an injury, spasm, infection, or cramp. Loss of blood flow to the muscle can be one of the cause for muscle pain and inflammation. Joint pain due to rheumatoid arthritis (immune disorder) and osteoarthritis can be another contributing factor in causing the pain. Another pain-inducing factor can be nerve compression pain due to high pressure on the nerves.
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Alcohol
Unsafe
Dolostat MR Tablet 10's with alcohol can cause liver problems, so should not be taken until prescribed if you are taking alcohol.
Pregnancy
Safe if prescribed
Only consume Dolostat MR Tablet 10's, if you are prescribed by a doctor.
Breast Feeding
Safe if prescribed
Only consume Dolostat MR Tablet 10's, if you are prescribed by a doctor
Driving
Unsafe
Dolostat MR Tablet 10's can impair the ability to drive. So, do not drive or operate heavy machinery that required mental alertness after taking Dolostat MR Tablet 10's.
Liver
Caution
Dolostat MR Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.
Kidney
Caution
Dolostat MR Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Children
Safe if prescribed
Dolostat MR Tablet 10's is not recommended for children below the age of 10 years. The safety and effectivenss of Dolostat MR Tablet 10's has not been established in children due to limited testing of this drug on children by competent authorities across the world.
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