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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

TRAMADOL-50MG

Manufacturer/Marketer :

Unichem International

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Domadol 50 mg Injection

Domadol 50 mg Injection belongs to a class of medicines called opioid analgesics (pain killers). Domadol 50 mg Injection is primarily used in the treatment of moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). 

Domadol 50 mg Injection contains Tramadol that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to brain. Also, Domadol 50 mg Injection improves the effect of serotonin and noradrenaline (chemical messengers in brain and spinal cord) and helps in relieving pain. 

Domadol 50 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation or sweating. Most of these side effects of Domadol 50 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor. 

If you are known to be allergic to Domadol 50 mg Injection or any other medicines, please tell your doctor. Domadol 50 mg Injection is not recommended for children suffering from breathing problems. If you are pregnant or breastfeeding or have history of fits, please inform your doctor before taking Domadol 50 mg Injection. Do not consume alcohol with Domadol 50 mg Injection as it may increase the risk of side effects. Avoid frequent or high doses as it may lead to addiction.

Uses of Domadol 50 mg Injection

Moderate to severe pain

Directions for Use

Domadol 50 mg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Domadol 50 mg Injection is a pain killer that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, Domadol 50 mg Injection improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Domadol 50 mg Injection is used to relieve pain after surgery, pain caused by an injury or illness. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Tramadol or any other medicines, please tell your doctor. Domadol 50 mg Injection is not recommended for children suffering from breathing problems as it may worsen the symptoms of tramadol toxicity. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking Domadol 50 mg Injection. Do not consume alcohol with Domadol 50 mg Injection as it may increase the risk of side effects. Domadol 50 mg Injection may cause withdrawal symptoms if stopped abruptly. Avoid frequent or high doses as it may lead to addiction. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Domadol 50 mg Injection:
Taking Safinamide with Domadol 50 mg Injection can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Domadol 50 mg Injection is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Domadol 50 mg Injection:
Co-administration of Linezolid with Domadol 50 mg Injection can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Domadol 50 mg Injection is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolAlvimopan
Critical
How does the drug interact with Domadol 50 mg Injection:
Co-administration of Domadol 50 mg Injection with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Domadol 50 mg Injection is not recommended, please consult your doctor before taking it.
How does the drug interact with Domadol 50 mg Injection:
Taking rasagiline with Domadol 50 mg Injection can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Domadol 50 mg Injection with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Domadol 50 mg Injection:
Co-administration of Ziprasidone with Domadol 50 mg Injection can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Domadol 50 mg Injection with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Domadol 50 mg Injection:
Combining Tranylcypromine with Domadol 50 mg Injection can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Domadol 50 mg Injection is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TramadolPhenelzine
Critical
How does the drug interact with Domadol 50 mg Injection:
Combining Phenelzine with Domadol 50 mg Injection can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Domadol 50 mg Injection with Phenelzine is not recommended, please consult your doctor before taking it.
How does the drug interact with Domadol 50 mg Injection:
Co-administration of olanzapine with Domadol 50 mg Injection can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking olanzapine with Domadol 50 mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Domadol 50 mg Injection:
Co-administration of bupropion with Domadol 50 mg Injection may increase the risk and severity of the seizure.

How to manage the interaction:
Taking bupropion with Domadol 50 mg Injection together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Domadol 50 mg Injection:
Co-administration of sotalol with Domadol 50 mg Injection can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking sotalol and Domadol 50 mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercises such as swimming or walking. 
  • Drink plenty of water while taking Domadol 50 mg Injection to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Domadol 50 mg Injection.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC

Domadol 50 mg Injection Substitute

Substitutes safety advice
  • Kamadol-100Mg/2Ml Injection

    by AYUR

    9.00per tablet
  • I Pain X 50 Injection 2 ml

    by Others

    10.35per tablet
  • CONTRAMAL INJECTION 1ML

    by Others

    20.70per tablet
  • Critidol 50mg Injection 1ml

    by AYUR

    11.70per tablet
  • Critidol 50Mg/2Ml Inj

    by AYUR

    23.81per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Domadol 50 mg Injection works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibiting the transmission of pain signals from nerves to the brain. Also, Domadol 50 mg Injection improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.

Domadol 50 mg Injection may cause withdrawal symptoms such as irritability, anxiety, restlessness, difficulty in sleeping, palpitations (feeling your heartbeat), feeling sick, shivering, sweating, high blood pressure and shaking when you stop taking Domadol 50 mg Injection suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Domadol 50 mg Injection may cause dry mouth as a common side effect. It is not necessary for everyone taking Domadol 50 mg Injection to experience this side effect. Drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent dry mouth. If the condition worsens or persists, please consult a doctor.

Domadol 50 mg Injection may cause fits, especially when taken in high doses or if you have a history of fits. Therefore, it is recommended to inform your doctor if you ever had fits as it may increase the chance of getting fits.

You are not recommended to take Domadol 50 mg Injection with antidepressants (medicines used to treat depression) and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Domadol 50 mg Injection may increase the risk of fits. However, please consult a doctor before taking Domadol 50 mg Injection with other medicines.

Yes, Domadol 50 mg Injection may cause addiction especially if taken for a prolonged time. Therefore, Domadol 50 mg Injection should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Domadol 50 mg Injection only as advised by a doctor as overuse or misuse of Domadol 50 mg Injection can lead to overdose or death.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • ONDANSETRON
  • FLUOXETINE
  • DOXEPIN
  • DROPERIDOL
  • MORPHINE
  • CODEINE
  • WARFARIN

Special Advise

  • Patients with severe liver or kidney insufficiency should avoid taking Domadol 50 mg Injection. 

Disease/Condition Glossary

Pain: It is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain, cuts, flu, irritable bowel syndrome (intestinal disorder causing stomach pain, diarrhoea or constipation), fibromyalgia (muscle pain with stiffness and tenderness), certain disease conditions, or medical procedures.

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