Donep-M Tablet 10's

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Prescription drug

Whats That

About Donep-M Tablet

Donep-M Tablet is a combination drug containing a 'neurological medicine,' primarily used to treat Alzheimer's disease (memory loss). Alzheimer's disease is a progressive neuro disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells (neurons) to die.

Donep-M Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor that works by preventing the breakdown of the chemical acetylcholine and improving the function of nerve cells in the brain. Memantine works by lowering the level of the chemical in the brain which is responsible to cause symptoms of Alzheimer's disease. Together, both of them balance the levels of chemical messengers in the brain and help transmit nerve signals.

Take Donep-M Tablet as prescribed by your doctor. You are advised to take Donep-M Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it before just bedtime. In some cases, you may experience vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhoea, and headache. Most of these side effects of Donep-M Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Donep-M Tablet may cause dizziness and sleepiness. So, do not drive a car or operate any machinery that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking Donep-M Tablet as it may cause diarrhoea. Before using Donep-M Tablet , inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma.

Uses of Donep-M Tablet

Alzheimer’s disease (memory loss)

Directions for Use

Swallow Donep-M Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Medicinal Benefits

Donep-M Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals. Donepezil is a cholinesterase inhibitor that works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain, which is responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.

Storage

Keep Donep-M Tablet out of the sight and reach of children.

Side effects of Donep-M Tablet

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Stomach Ache

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Toothache

Uncontrolled Bowel Movements

Discuss with your doctor the use of medications like antidiarrheals, laxatives, or stool bulking agents to control bowel movements.
Drink enough water to help loosen stool and ease bowel movements.
Consume foods high in fiber to encourage regular bowel movements and avoid constipation, such as spinach, bananas, berries, and brown rice.
Regular exercises improve bowel functionality and a healthy condition altogether.
Do Kegel exercises to strengthen pelvic floor muscles and bowel control.

Drug Warnings

Do not take Donep-M Tablet if you are allergic to Donep-M Tablet or any of its ingredients. Donep-M Tablet may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking Donep-M Tablet as it may cause diarrhoea. Before using Donep-M Tablet , inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. Take Donep-M Tablet preferably just before bedtime.

Drug-Drug Interactions

DonepezilTramadol

Severe

DonepezilIopamidol

Severe

Drug-Drug Interactions

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DonepezilTramadol

Severe

How does the drug interact with Donep-M Tablet:
Coadministration of Donep-M Tablet with tramadol can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Taking Donep-M Tablet with tramadol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, increased heart rate, blurred vision, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

DonepezilIopamidol

Severe

How does the drug interact with Donep-M Tablet:
The combined use of iopamidol and Donep-M Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizures or head injury.

How to manage the interaction:
Taking Donep-M Tablet with Iopamidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not stop using any medications without a doctor's advice.

DonepezilIomeprol

Severe

How does the drug interact with Donep-M Tablet:
Co-administration of Iomeprol and Donep-M Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Co-administration of Donep-M Tablet with Iomeprol can possibly result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor if you experience any symptoms like shortness of breath, irregular heart rhythms, or problems with movement and memory. Do not discontinue any medications without first consulting your doctor.

DonepezilIohexol

Severe

How does the drug interact with Donep-M Tablet:
Coadministration of Iohexol and Donep-M Tablet can increase the risk of developing seizures. The risk increases in patients with a history of seizure or head injury.

How to manage the interaction:
Although taking Donep-M Tablet and Iohexol together can cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without first talking to your doctor.

DonepezilCyclopentolate

Severe

How does the drug interact with Donep-M Tablet:
Coadministration of Cyclopentolate with Donep-M Tablet can reduce the levels and effects of Cyclopentolate.

How to manage the interaction:
There may be a possibility of interaction between Cyclopentolate and Donep-M Tablet, but it can be taken when prescribed by a doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, or rapid heartbeat consult your doctor immediately. Do not stop using any medications without talking to your doctor.

DonepezilBupropion

Severe

How does the drug interact with Donep-M Tablet:
Taking bupropion with Donep-M Tablet may increase the levels of Donep-M Tablet and the risk of developing seizures.

How to manage the interaction:
Co-administration of bupropion along with Donep-M Tablet can lead to an interaction, but it can be taken when recommended by a doctor. However, if you experience sudden dizziness, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

DonepezilMetrizamide

Severe

How does the drug interact with Donep-M Tablet:
The combined use of metrizamide and Donep-M Tablet can increase the risk of developing seizures. If you have a history of seizures or a head injury, contact your doctor immediately.

How to manage the interaction:
Although there is a possible interaction between Donep-M Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Find the humour in your daily life. Try to watch light-hearted shows to help relieve stress.
You can try increasing your mindfulness, by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve diarrhoea.
Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
Try to spend time with your friends and family. Having a strong social network may help you lower your risk of memory loss.

Side Effects of Donep-M Tablet

Vomiting
Loss of appetite
Dryness in the mouth
Dizziness
Weight loss
Nausea
Diarrhoea
Headache

Habit Forming

No

Therapeutic Class

CENTRAL NERVOUS SYSTEM AGENTS

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Donep-M Tablet work?

Donep-M Tablet is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. Donepezil works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain, which is responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.

I need to undergo surgery, can I talk Donep-M Tablet ?

No, it is recommended not to take Donep-M Tablet before s surgery as it contains Donepezil, which is a cholinesterase inhibitor and is likely to exaggerate muscle relaxation during anaesthesia. So, please inform your doctor before surgery if you are taking Donep-M Tablet as he might stop it &2 hours before undergoing surgery.

Can the use of Donep-M Tablet cause diarrhea?

Yes, the use of Donep-M Tablet can cause diarrhoea. In some cases, the patient may experience diarrhoea. So, please increase the intake of fluids to avoid dehydration. And also do not take any other medicines without speaking to a doctor.

Can Donep-M Tablet cause weight loss?

Yes, Donep-M Tablet is known to cause weight loss. So, while taking Donep-M Tablet , you should constantly monitor your body weight to avoid major weight loss.

What happens if more than the recommended dose of Donep-M Tablet is taken?

Taking Donep-M Tablet in more than the recommended dose can cause unpleasant side-effects such as dizziness, tremor, agitation, convulsion, coma, nausea, vomiting, changes in heart rhythm, decreased blood pressure, and change in body fluid/salt balance.

I am 65 years, is Donep-M Tablet safe for me?

Yes, Alzheimer's disease (memory loss) generally occurs in people who are elderly and aged. So, Donep-M Tablet is safe for the elderly population, but the dose should be given by a doctor depending upon any underlining disease condition you are suffering from. Also, never self medicate.

Drug-Drug Interactions Checker List

ASPIRIN
DONEPEZIL
AMANTADINE
KETOCONAZOLE
PHENYTOIN
CARBAMAZEPINE
DEXAMETHASONE
PHENOBARBITAL
CIMETIDINE
RANITIDINE
BROMOCRIPTINE

Special Advise

Donep-M Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention like driving when on this drug.
Avoid consuming alcohol while on this medication as it can lead to dangerous side effects.
The safety and efficacy are not established in pregnant or breastfeeding. Discuss with your doctor in such situations about changing/replacing the medicine with safer alternatives.
Do not self-medicate.

Disease/Condition Glossary

Alzheimer's disease: It is a progressive neurologic disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells to die. One of the very common causes of Alzheimer's disease is dementia (memory loss), which affects the person's ability to function independently. Very early signs of the disease are forgetting recent events and conversations, and as the disease progresses, it can lead to severe memory impairment.