Donibiz-10 Tablet 10's

Donibiz-10 Tablet 10's belongs to the group of medicines called 'anti-Alzheimer's drug', primarily indicated in the treatment of dementia of the Alzheimer’s disease. In Alzheimer's disease, the brain cells degenerate and die, which causes a gradual decline in behavioural and social skills and thinking ability (dementia), which affects a person's ability to function independently. The signs include confusion, increasing memory loss, and behavioural changes.

Donibiz-10 Tablet 10's contains Donepezil that falls in the category of drugs called acetylcholinesterase inhibitors. This drug increases the levels of a substance (acetylcholine) in the brain, which is involved in improving memory functioning by slowing down the breakdown of acetylcholine (a substance that allows nerves to communicate and important for normal brain functioning).

Take Donibiz-10 Tablet 10's as prescribed. Your doctor will recommend you how often you take Donibiz-10 Tablet 10's based on your medical condition. A person taking Donibiz-10 Tablet 10's may experience some undesirable effects of this medicine like insomnia, diarrhoea, muscle cramps, vomiting, fatigue, weight loss, and nausea. This happens because the body is adjusting to the new medicine. If a person notices severe side effects of medicine like dizziness, constipation, drowsiness, fainting, frequent urination, headache, joint pain, mental depression, and pain, or if side effects do not go within a couple of days, then they need to consult with the doctor immediately.

A person cannot take Donibiz-10 Tablet 10's if they are hypersensitive to any of the components present in this medicine. A person facing medical conditions like a heart rhythm disorder, a stomach ulcer, urination problems, asthma or other breathing disorder, seizure, and liver or kidney disease need to tell their doctor before taking this medicine. A woman who is pregnant or breastfeeding needs to tell their doctor before taking this medicine. This medicine should be prescribed with caution in patients having a history of asthma or obstructive pulmonary disease.

Donibiz-10 Tablet 10's belongs to the category of the acetylcholinesterase inhibitors, prescribed for treating the symptoms of dementia in persons having mild and moderately severe Alzheimer's disease. Donibiz-10 Tablet 10's works by helping the nerve cells communicate with each other by increasing acetylcholine levels in the brain. It stops the breakdown of acetylcholine in the brain, which is an important substance that is responsible for nerve communication. By doing so it helps a person to live a normal life.

• Diarrhoea
• Loss of appetite
• Muscle cramps
• Nausea
• Trouble in sleeping
• Unusual tiredness
• Weakness
• Vomiting

A person should tell their doctor if they are taking any prescription or herbal medicine as certain medicines may weaken or strengthen the effects of Donibiz-10 Tablet 10's. A person should avoid the consumption of alcohol as it may reduce the effects of medication.  A woman who is pregnant or breast-feeding should ask their doctor for advice before taking this medicine. Alzheimer’s disease may affect the ability to drive so a person must not perform any activity that needs mental alertness unless your doctor tells you that it is safe to do so.

Drug-drug Interactions: Some medications may change the working action of Donibiz-10 Tablet 10's so tell your doctor about every prescription/nonprescription drugs and herbal products you are using. The possible drugs that can interact with Donibiz-10 Tablet 10's include NSAIDs (such as ibuprofen, naproxen), antihistamine (Diphenhydramine), anticoagulant medication (apixaban), anticholinergics medicines, (tolterodine), and anti-depressants (fluoxetine).

Drug- Food Interactions: Food will not influence the effect of Donibiz-10 Tablet 10's, but a person should not be taken with alcohol because alcohol may reduce its effect.

Drug-Disease Interactions: A person should tell their doctor if they are dealing with a heart rhythm disorder, a stomach ulcer, urination problems, asthma or other breathing disorder, liver or kidney disease, and a seizure.

• IBUPROFEN
• NAPROXEN
• DIPHENHYDRAMINE
• APIXABAN
• TOLTERODINE
• FLUOXETINE

• A person dealing with Alzheimer's disease needs to take proper nutrition to make their body strong and healthy. For a patient dealing with dementia, poor nutrition can affect behavioral symptoms and may cause weight loss.
• Consume more whole grains, low-fat dairy products, vegetables, fruits, and lean protein foods, and cut down high saturated fat, refined sugars, and cholesterol from your diet.
• Patients dealing with dementia should do meditation activities that help calm down their minds and make medicine work more efficiently.
• Do physical exercises that are safe for Alzheimer/ dementia patients.

Certain Cognitive and neuropsychological tests are done to diagnose dementia.

Alzheimer's disease: It is a chronic progressive disease in which the brain cells degenerate and die and is the most common cause of dementia.  Dementia affects a person's ability to function independently and affects a person's thinking, judgment, behaviour, and memory. Persons dealing with this disease face symptoms like memory loss that affects daily activities, difficulty in doing familiar tasks and problem-solving, trouble in speech or writing, decreased judgment /personal hygiene, and personality changes.