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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Tas Med India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dotin M 75mg/1500mcg Tablet

Dotin M 75mg/1500mcg Tablet belongs to the class of medications called antidepressants used in the treatment of depression. Depression is a neurological disease. It is a mood disorder characterized by persistent feelings of sadness, loss, or anger. This condition can also be triggered by vitamin b12 deficiency. Your doctor prescribes Dotin M 75mg/1500mcg Tablet when other medications are ineffective to treat depression. 

Dotin M 75mg/1500mcg Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Dosulepin is a tricyclic antidepressant that increases neurotransmitter's activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

The dose is determined by your doctor based on your health condition. The common side-effects of Dotin M 75mg/1500mcg Tablet are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.

Do not take Dotin M 75mg/1500mcg Tablet if you are allergic to any content of it. Do not take Dotin M 75mg/1500mcg Tablet if you have an irregular heartbeat or any other heart problems, liver problems, eye condition known as glaucoma, prostate problems in men (difficulty in passing water or enlarged prostate), mania (feeling over-excited with unusual behaviour), and epilepsy (fits). It should be used with caution in young adults as it can increase worsen depression and cause suicidal thoughts. If you have thoughts of harming yourself, consult your doctor immediately. Inform your doctor if you are pregnant or breastfeeding. 

Uses of Dotin M 75mg/1500mcg Tablet

Depression

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Dotin M 75mg/1500mcg Tablet is a combination of two medicines: Dosulepine and Methylcobalamin. Your doctor prescribes this medication when other medications are ineffective to treat depression. Dosulepin is a tricyclic antidepressant that increases neurotransmitters' activity, namely serotonin, and noradrenaline in the brain. Serotonin helps in enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. Noradrenaline helps in improving mood, alertness, and the ability to concentrate. Methylcobalamin helps to treat vitamin b12 deficiency.

Storage

Keep Dotin M 75mg/1500mcg Tablet out of the sight and reach of children.
Side effects of Dotin M 75mg/1500mcg Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Maintain consistent habits, sleep patterns and food times to help maintain stability and reduce confusion.
  • Mindfulness techniques such as deep breathing or meditation help you stay focused and in the now.
  • Participate in cognitive therapy to enhance your ability to remember, focus and solve problems.
  • As directed by your physician, take your medications to help control underlying disorders like depression, anxiety or cognitive impairment.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

Drug Warnings

Before taking Dotin M 75mg/1500mcg Tablet, inform your doctor if you are undergoing surgery, have diabetes, receiving electroshock therapy (ECT), have thyroid problems, difficulty in passing urine, adrenal gland tumour, have porphyria (disease-causing damage to the nerves and skin sensitivity), have a history of mania or psychosis, have cardiac disease, have severe renal disease, and have epilepsy (fits). It increases suicidal tendencies, especially in young adults.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of paroxetine and Dotin M 75mg/1500mcg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although taking Dotin M 75mg/1500mcg Tablet and paroxetine together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience confusion, increased heart rate, fever, excessive sweating, blurred vision, muscle spasms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Amitriptyline and Dotin M 75mg/1500mcg Tablet may increase the risk of irregular heartbeat. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although combining Amitriptyline with Dotin M 75mg/1500mcg Tablet may result in an interaction, it can be used when a doctor recommends it. If you experience sudden dizziness or irregular heartbeats during therapy, contact your doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Dotin M 75mg/1500mcg Tablet with Chloramphenicol can impair absorption and increase the levels of Dotin M 75mg/1500mcg Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dotin M 75mg/1500mcg Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dotin M 75mg/1500mcg Tablet:
Coadministration of Dotin M 75mg/1500mcg Tablet with Neomycin can impair the absorption of Dotin M 75mg/1500mcg Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Dotin M 75mg/1500mcg Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced diet.
  • Avoid processed or packed foods and foods that are high in refined sugars.
  • Exercise regularly.
  • Lose excess weight and keep a check on your weight.
  • Avoid stress.
  • Improve your mood by being active, socializing with others, and talking about your feelings.
  • Quit alcohol intake and smoking.

 

Side Effects of Dotin M 75mg/1500mcg Tablet

  • Dry mouth
  • Blurred vision
  • Headache
  • Increase or decrease in appetite
  • Nausea or vomiting
  • Diarrhoea
  • Changes in heartbeat
  • Constipation
  • Difficulty in passing urine
  • Sweating

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

Dotin M 75mg/1500mcg Tablet Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dotin M 75mg/1500mcg Tablet contains Dosulepin and Methylcobalamin. It treats depression by enhancing mood, improving memory, and also reduces problems associated with sleeping and eating. It also treats vitamin B12 deficiency which is a risk factor for depression.

Dotin M 75mg/1500mcg Tablet should not be used in patients with heart problems as it may worsen the condition. Discuss with your doctor about the potential benefits and risks before using Dotin M 75mg/1500mcg Tablet.

The common side-effects of Dotin M 75mg/1500mcg Tablet are dry mouth, blurred vision, headache, increase or decrease in appetite, nausea or vomiting, diarrhoea, changes in heartbeat, constipation, difficulty in passing urine, and sweating. If the symptoms persist or worsen, consult a doctor immediately.

Dotin M 75mg/1500mcg Tablet should not be used in patients with thyroid problems as it may exacerbate the condition by causing iatrogenic effects (drug-inducing side-effects). So, discuss the risks and benefits of this medication with your doctor before using Dotin M 75mg/1500mcg Tablet.

Dotin M 75mg/1500mcg Tablet increases suicidal thoughts and worsens the depression in young adults. Your doctor may prescribe this medicine with dose adjustments. So, do not use Dotin M 75mg/1500mcg Tablet without consulting your doctor.

Drug-Drug Interactions Checker List

  • OMEPRAZOLE
  • CIMETIDINE
  • HALOFANTRINE
  • TERFENADINE
  • ASTEMIZOLE
  • TRAMADOL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • WARFARIN
  • RITONAVIR
  • NEOMYCIN
  • RIFAMPICIN

Disease/Condition Glossary

Depression: Depression is a mental health disorder in which patients experience persistent loss of interest or mood and feelings of sadness. It affects quality-of-life. It causes changes in sleep, appetite, social behaviour, learning abilities, concentration, and self-esteem. This condition can also be triggered by vitamin B12 (cyanocobalamin) deficiency.

Have a query?

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Alcohol

Caution

Alcohol increases the risk of side-effects.

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Pregnancy

Unsafe

Dotin M 75mg/1500mcg Tablet is a category C drug. So, it is not recommended for use in pregnant women.

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Breast Feeding

Caution

Dotin M 75mg/1500mcg Tablet should be used with caution in breastfeeding mothers.

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Driving

Caution

Dotin M 75mg/1500mcg Tablet may cause drowsiness. So, do not drive or operate heavy machinery while taking this medicine.

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Liver

Caution

Dotin M 75mg/1500mcg Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Dotin M 75mg/1500mcg Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Caution

Dotin M 75mg/1500mcg Tablet should not be used in children below 12 years of age without a doctor's advice.

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