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Reviewed By Sunny S , MBBS
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Composition :

DOXYCYCLINE-50MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dox 50 mg Tablet

Dox 50 mg Tablet belongs to a group of medications called tetracycline antibiotics, used to treat bacterial infections. Dox 50 mg Tablet treats urinary tract infections, intestinal infections, respiratory infections, eye infections, sexually transmitted infections (like gonorrhoea, syphilis), gum infections, diseases (like periodontitis), and others. Besides this, Dox 50 mg Tablet also treats acne-like lesions caused by rosacea. However, it does not treat facial redness caused by rosacea. 

Dox 50 mg Tablet being an antibiotic prevents the growth of bacterial cells (the bad ones!) by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.

Dox 50 mg Tablet should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. You should complete the course of Dox 50 mg Tablet as your doctor prescribes for better results. Some common side effects of Dox 50 mg Tablet are nausea (feeling or being sick), vomiting, diarrhoea etc. Please consult your doctor if these side effects become troublesome.

Dox 50 mg Tablet is pregnancy category D (high risk) medicines, so its use in pregnant and nursing mothers is not recommended. Use of Dox 50 mg Tablet during tooth development (last half of pregnancy, infancy, and childhood up to the age of 8 years) may cause teeth staining (yellow-grey-brown). Do not consume alcohol as it may cause excessive drowsiness when taken along with Dox 50 mg Tablet . Before using Dox 50 mg Tablet , tell your doctor if you ever had an allergy to Dox 50 mg Tablet , have kidney problems, liver problems, swollen food pipe (esophagitis) or muscle disease (myasthenia gravis). Please do not drink alcohol with Dox 50 mg Tablet as it may increase the unpleasant side effects like drowsiness and dizziness. 

Uses of Dox 50 mg Tablet

Bacterial infections

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Dox 50 mg Tablet is a type of tetracycline class of antibiotic which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is prescribed for treating various bacterial infections of the respiratory tract (influenza, pneumonia), genitourinary area (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prophylaxis or prevention of malaria in the prone area and the treatment of acne. Sometimes your doctor might prescribe you Dox 50 mg Tablet as an alternative medicine to penicillin when penicillin is contraindicated.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dox 50 mg Tablet

  • Nausea (feeling sick)
  • Vomiting
  • Diarrhoea

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Dox 50 mg Tablet in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Dox 50 mg Tablet and iron supplements and antacids. Prolonged use of Dox 50 mg Tablet during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discolouration of the teeth (yellow-grey-brown). Besides this, in some cases, the use of Dox 50 mg Tablet causes antibiotic-associated diarrhoea. Dox 50 mg Tablet may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Dox 50 mg Tablet can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Dox 50 mg Tablet with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Dox 50 mg Tablet may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended. Dox 50 mg Tablet  does not completely prevent malaria caused by P. falciparum as a Dox 50 mg Tablet is given only for the prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Drug-Drug Interactions

verifiedApollotooltip
DoxepinProcarbazine
Critical
DoxepinTranylcypromine
Critical

Drug-Drug Interactions

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DoxepinProcarbazine
Critical
How does the drug interact with Dox 50 mg Tablet:
Combining Procarbazine and Dox 50 mg Tablet can increase the risk of a rare but serious condition called the serotonin syndrome(build up high levels of serotonin in the body).

How to manage the interaction:
Taking Dox 50 mg Tablet with Procarbazine is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. you should wait at least 14 days after stopping procarbazine before you start treatment with Dox 50 mg Tablet and do not discontinue any medications without consulting your doctor.
DoxepinTranylcypromine
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Dox 50 mg Tablet with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dox 50 mg Tablet with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DoxepinSaquinavir
Critical
How does the drug interact with Dox 50 mg Tablet:
Combining Dox 50 mg Tablet with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dox 50 mg Tablet with Saquinavir is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DoxepinRasagiline
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Rasagiline with Dox 50 mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Dox 50 mg Tablet with rasagiline is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms, like confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms, stomach cramps, nausea, vomiting, and loose stools, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DoxepinPotassium chloride
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Dox 50 mg Tablet with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Dox 50 mg Tablet with Potassium chloride is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DoxepinPotassium citrate
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Dox 50 mg Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Dox 50 mg Tablet with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, consult the doctor immediately if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools. Do not discontinue any medications without a doctor's advice.
DoxepinSafinamide
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Safinamide with Amitriptyline can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dox 50 mg Tablet with Safinamide is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
DoxepinDronedarone
Critical
How does the drug interact with Dox 50 mg Tablet:
Combining Dox 50 mg Tablet with Dronedarone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Dox 50 mg Tablet with Dronedarone is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DoxepinZiprasidone
Critical
How does the drug interact with Dox 50 mg Tablet:
Taking Dox 50 mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Dox 50 mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DoxepinVandetanib
Severe
How does the drug interact with Dox 50 mg Tablet:
Co-administration of vandetanib with Dox 50 mg Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking vandetanib with Dox 50 mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Dox 50 mg Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Dox 50 mg Tablet .
  • Avoid intake of alcoholic beverages with Dox 50 mg Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Dox 50 mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Dox 50 mg Tablet Substitute

Substitutes safety advice
  • Novadox Dry Syrup

    by Others

    1.63per tablet
  • Sandox CP 50mg Dry Syrup

    by Others

    1.50per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dox 50 mg Tablet being an antibiotic prevents the growth of bacterial cells (the bad ones!) by preventing the formation of the outer protein layer of bacteria (cell wall) responsible for bacteria's growth and multiplication. It is a broad-spectrum antibiotic, i.e. it acts against various bacteria. It is a bacteriostatic antibiotic, i.e. it stops bacteria growth but does not kill them.

No, Dox 50 mg Tablet should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary, otherwise the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.

The expiration date of any drug is the last day the manufacturer takes a guarantee of the full potency of the drug. Dox 50 mg Tablet should not be taken after its expiry date as it can cause kidney damage if taken after its expiry.

If you are taking Dox 50 mg Tablet , avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Dox 50 mg Tablet as they may affect the absorption of Dox 50 mg Tablet from the stomach. Avoid taking dairy products within 2 hours of taking Dox 50 mg Tablet as they also impair the absorption of Dox 50 mg Tablet .

Acohol may reduce the effect of Dox 50 mg Tablet . It is therefore advisable to avoid drinking any alcohol while you are taking Dox 50 mg Tablet .

Use of Dox 50 mg Tablet during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.

Yes. Intake of Dox 50 mg Tablet may increase your skin sensitivity to the sun rays or ultraviolet lights. So, it is better to apply any sunscreen lotions on your skin whenever you step out of your home.

Yes. Intake of Dox 50 mg Tablet may lead to overgrowth of fungal skin infections like candida. This happens because Dox 50 mg Tablet also kills good or beneficial bacteria that protect against thrush. If such symptoms occur reach out to your doctor.

Dox 50 mg Tablet generally does not affect any contraception, including the birth control pill and emergency contraceptive pills. However, if you develop vomiting or have diarrhoea, your birth control pill may not protect you from pregnancy. Please consult your doctor if you have any concerns regarding using the Dox 50 mg Tablet .

Drug-Drug Interactions Checker List

  • ACITRETIN
  • ISOTRETINOIN
  • WARFARIN
  • DIGOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • BISMUTH SUBSALICYLATE

Special Advise

  • Dox 50 mg Tablet is preferably taken empty stomach or 1-2 hours before meals but it can lead to stomach upset. To avoid this, you may take Dox 50 mg Tablet with meals but ensure you drink plenty of water to keep yourself hydrated.
  • To prevent throat irritation take Dox 50 mg Tablet in an upright position. Do not lie down for at least 30 minutes of taking it. 
  • Even if you feel better after taking Dox 50 mg Tablet , do not stop taking it until your doctor says so. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.
  • Dox 50 mg Tablet can affect growing teeth, so it should be avoided during pregnancy and in children less than 8 years old.
  • Dox 50 mg Tablet should not be consumed beyond its expiry date as after that it breaks down into harmful chemicals which can damage the kidney.
  • Make sure you drink plenty of fluids when you are sick. This will in general help you clear out the infection faster, protect you from dehydration, and will help you overcome some unpleasant side effects of taking Dox 50 mg Tablet .
  • Wear sunglasses and sunscreen when you go out in the sun as Dox 50 mg Tablet can make your skin sensitive to light.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E.coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

Rosacea: Rosacea is a skin infection that causes a persistent redness in the centre of your face. Small blood vessels on the cheeks and nose are often inflamed and red. Many people with rosacea also develop pimples on their faces, similar to acne.

Antibiotic-induced diarrhoea: Antibiotic-induced diarrhoea or Antibiotic-associated diarrhoea refers to the occurrence of diarrhoea (passing loose, watery stools more than 3 times per day) after taking antibiotics. It happens because antibiotics also kill beneficial intestinal bacteria (gut flora) which aids in the food digestions and fighting off infections.  

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