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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy

About Doxinate 24 Tablet 15's

Doxinate 24 Tablet 15's belongs to the class of medications called “anti-emetics” primarily used to treat nausea and vomiting during pregnancy. It helps treat morning sickness (nauseous feeling during the first trimester) in pregnant women. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the body's natural response to discharge the stomach content forcefully.

Doxinate 24 Tablet 15's is a combination of two drugs, namely: Doxylamine succinate and Pyridoxine hydrochloride (vitamin B6). Doxylamine succinate belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine hydrochloride works by increasing the level of vitamin B6 in the body and thus treating nausea and vomiting during pregnancy.

You are advised to take Doxinate 24 Tablet 15's for as long as your doctor has prescribed it, depending on your medical condition. In some cases, you may experience certain common side effects, such as dizziness, stomach pain, constipation, and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are allergic to Doxinate 24 Tablet 15's or any other medicines, please tell your doctor. Consult your doctor before taking Doxinate 24 Tablet 15's if you are pregnant, planning for pregnancy, or breastfeeding. Doxinate 24 Tablet 15's may make you dizzy or drowsy, hence avoid driving if you are not alert mentally. Avoid consuming alcohol along with Doxinate 24 Tablet 15's as it could lead to increased drowsiness. Doxinate 24 Tablet 15's is not recommended for anyone below 18 years of age as the safety and efficacy have not been established. 

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Doxinate 24 Tablet 15's

Treatment of nausea and vomiting in pregnancy.

Medicinal Benefits

Doxinate 24 Tablet 15's is a combination of two drugs, namely: Doxylamine succinate and Pyridoxine hydrochloride (vitamin B6). It is used to treat nausea and vomiting during pregnancy. Doxylamine succinate belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine hydrochloride works by increasing the level of vitamin B6 in the body and treats nausea and vomiting during pregnancy.

Side Effects of Doxinate 24 Tablet 15's

  • Dizziness
  • Stomach pain
  • Constipation
  • Dry mouth

Directions for Use

Swallow it as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Doxinate 24 Tablet 15's if you are allergic to any of its contents. Tell your doctor if you have a medical history of asthma, glaucoma, stomach ulcer or a blockage in your gut (digestive tract), liver, and kidney problems before starting Doxinate 24 Tablet 15's. Please consult your doctor if you are pregnant or breastfeeding. Doxinate 24 Tablet 15's may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol along with Doxinate 24 Tablet 15's as it could lead to increased dizziness. Doxinate 24 Tablet 15's is not recommended in children below 18 years of age.

Therapeutic Class

ANTIEMETICS

Drug-Drug Interactions

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DoxylamineTranylcypromine
Critical
DoxylamineFentanyl
Severe

Drug-Drug Interactions

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DoxylamineTranylcypromine
Critical
How does the drug interact with Doxinate 24 Tablet 15's:
Taking Doxinate 24 Tablet 15's with tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Doxinate 24 Tablet 15's and Tranylcypromine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DoxylamineFentanyl
Severe
How does the drug interact with Doxinate 24 Tablet 15's:
Taking Doxinate 24 Tablet 15's with Fentanyl together can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Doxinate 24 Tablet 15's with Fentanyl can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you feel drowsiness, loss of balance, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
DoxylaminePotassium citrate
Severe
How does the drug interact with Doxinate 24 Tablet 15's:
Taking Doxinate 24 Tablet 15's and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Potassium citrate and Doxinate 24 Tablet 15's, but it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SELEGILINE
  • ISOCARBOXAZID
  • PHENELZINE
  • ALPRAZOLAM
  • CHLORDIAZEPOXIDE
  • LORAZEPAM
  • DIPHENHYDRAMINE
  • CHLORPHENIRAMINE

Diet & Lifestyle Advise

  • Limit taking foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids to prevent dehydration.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Morning sickness: It is a common symptom during pregnancy that usually happens within the first trimester (first three months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalance and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy. 

Nausea: It is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. 

Vomiting: It is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain or irritation to the stomach.

Doxinate 24 Tablet 15's Substitute

Substitutes safety advice
  • Doxinate-G Tablet 10's

    by AYUR

    12.06per tablet
  • Nvtab-OD Tablet 15's

    15.96per tablet
  • Doxebet 20 mg Tablet 10's

    11.07per tablet
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