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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Maneesh Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Doxinate Plus Tablet

Doxinate Plus Tablet belongs to the class of medications called ‘anti-emetics’ primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Morning sickness (nausea and vomiting during pregnancy) is a common symptom of pregnancy. It usually begins in the 6th week of pregnancy, lasting up to 16 to 18 weeks. However, some pregnant women have it throughout pregnancy. It can lead to electrolyte imbalances and weight loss in pregnant women.

Doxinate Plus Tablet contains Doxylamine, Pyridoxine, and Folic acid. Doxylamine is an antihistamine that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine is vitamin B6, and its deficiency may cause nausea and vomiting. It works by restoring the levels of vitamin B6 in the body and treating nausea and vomiting during pregnancy. Folic acid is also a form of vitamin B, which can provide essential nutrients during pregnancy.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Doxinate Plus Tablet are dizziness, drowsiness, dry mouth, tiredness and constipation. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Doxinate Plus Tablet if you are allergic to any contents of it. Before taking Doxinate Plus Tablet , inform your doctor if you have asthma, glaucoma (increased pressure in the eye), stomach ulcer, blockage in the stomach and small intestine, blockage in the bladder, and vitamin B12 deficiency. It is not recommended for use in children and breastfeeding mothers. Do not consume alcohol while taking this medicine as it may increase the risk of side-effects. Doxinate Plus Tablet may cause drowsiness and dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Doxinate Plus Tablet

Nausea and vomiting during pregnancy

Directions for Use

Take this medicine before food, i.e. 1 or 2 hours before a meal. Swallow Doxinate Plus Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Doxinate Plus Tablet belongs to the class of medications called ‘anti-emetics’ primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Doxinate Plus Tablet contains Doxylamine, Pyridoxine, and Folic acid. Doxylamine is an antihistamine that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine is vitamin B6 and its deficiency may cause nausea and vomiting. It works by restoring the levels of vitamin B6 in the body and treat nausea and vomiting during pregnancy. Folic acid is also a form of vitamin B which can provide essential nutrients during pregnancy.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Doxinate Plus Tablet is usually prescribed for pregnant women to prevent nausea and vomiting. So, do not use it for any other indication without consulting your doctor. It is not recommended to use Doxinate Plus Tablet along with monoamine oxidase (MAO) inhibitors (antidepressants). In addition, inform your doctor if you are receiving anticoagulant (blood thinners) therapy, sleeping pills, pain killers and cough or cold medicines. Do not stop taking this medicine abruptly as it may lead to the recurrence of your symptoms.

Drug-Drug Interactions

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DoxylaminePotassium citrate
Severe

Drug-Drug Interactions

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How does the drug interact with Doxinate Plus Tablet:
Taking Doxinate Plus Tablet with tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Doxinate Plus Tablet and Tranylcypromine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DoxylaminePotassium citrate
Severe
How does the drug interact with Doxinate Plus Tablet:
Taking Doxinate Plus Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Potassium citrate and Doxinate Plus Tablet, but it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Doxinate Plus Tablet:
Taking Doxinate Plus Tablet with Fentanyl together can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Doxinate Plus Tablet with Fentanyl can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you feel drowsiness, loss of balance, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Doxinate Plus Tablet:
Trimethoprim may decrease the blood levels and effects of Doxinate Plus Tablet.

How to manage the interaction:
Although there is a possible interaction between Doxinate Plus Tablet and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with Doxinate Plus Tablet:
Coadministration of Doxinate Plus Tablet and Cholestyramine may interfere with the absorption of Doxinate Plus Tablet.

How to manage the interaction:
Although taking Cholestyramine and Doxinate Plus Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Doxinate Plus Tablet:
Coadministration of Doxinate Plus Tablet and Carbamazepine may reduce the blood levels of Doxinate Plus Tablet.

How to manage the interaction:
Although there is a possible interaction between Doxinate Plus Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with Doxinate Plus Tablet:
Coadministration of Doxinate Plus Tablet and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Doxinate Plus Tablet and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with Doxinate Plus Tablet:
Co-administration of Doxinate Plus Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Doxinate Plus Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Doxinate Plus Tablet:
Sulfadiazine may decrease the blood levels and effects of Doxinate Plus Tablet.

How to manage the interaction:
Although there is a possible interaction between Doxinate Plus Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep good health and avoid chances of nausea and vomiting.
  • Avoid taking greasy or oily foods as this food triggers nausea and vomit.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has got lost due to vomiting.
  • Include more cool beverages in your food like clear soup, flavoured gelatin and carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • SELEGILINE
  • RASAGILINE
  • TRANYLCYPROMINE
  • ALPRAZOLAM
  • ZOLPIDEM
  • TRIAZOLAM
  • MORPHINE
  • METHADONE
  • BROMPHENIRAMINE
  • CHLORPHENIRAMINE
  • DIPHENHYDRAMINE

Special Advise

  • Doxinate Plus Tablet may cause false-positive results for drugs or pain medicines such as opiates or methadone when a urine drug screen is performed. So, inform your doctor that you are taking Doxinate Plus Tablet before undergoing this test. 
  • Do not take vitamin B supplementation in any form such as diet, multivitamins, or other supplements. 

Disease/Condition Glossary

Morning sickness (nausea and vomiting): It is a common symptom of pregnancy. It is usually happening within the first trimester (first four months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy. Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain or irritation to the stomach.

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