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  3. Doxybuz 100 mg Injection 1's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition :

DOXYCYCLINE-100MG

Manufacturer/Marketer :

Alniche Life Sciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Doxybuz 100 mg Injection

Doxybuz 100 mg Injection belongs to a group of medications called tetracycline antibiotics used to treat bacterial infections such as urinary tract infections, intestinal infections, respiratory infections, eye infections, skin infections, sexually transmitted infections (gonorrhoea, syphilis), and gum infections (periodontitis). Besides this, Doxybuz 100 mg Injection may also be used to treat or prevent anthrax.

Doxybuz 100 mg Injection contains 'Doxycycline' which stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxybuz 100 mg Injection helps treat bacterial infections. It is a broad-spectrum antibiotic which is effective against both gram-negative and gram-positive bacteria.

Doxybuz 100 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, Doxybuz 100 mg Injection may cause pain, itching, swelling or redness at the site of injection, nausea, vomiting, or diarrhoea. Most of these side effects of Doxybuz 100 mg Injection do not require medical attention and gradually resolve over time. Please consult your doctor if these side effects become troublesome.

Do not take Doxybuz 100 mg Injection if you are allergic to any of the components. Consult your doctor if you are pregnant or breastfeeding. Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Doxybuz 100 mg Injection

Bacterial infections

Directions for Use

Doxybuz 100 mg Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Doxybuz 100 mg Injection belongs to the class of medicines called tetracycline antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites. It is used to treat respiratory tract infections (influenza, pneumonia), genitourinary infections (syphilis, gonorrhoea), anthrax infection, sinuses, eye, and skin infections. Besides this, it is also indicated in the tick-borne infections (typhus fever) caused by the Rickettsia group of bacteria like typhus fever. Off-label, usage includes the prevention of malaria and the treatment of acne.

Storage

Keep out of sight and reach of children.
Side effects of Doxybuz 100 mg Injection
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
  • Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
  • Limit alcohol intake and abstain from smoking to promote general wellbeing.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.

Drug Warnings

Do not take Doxybuz 100 mg Injection if you are allergic to any of its contents. Inform your doctor if you have lupus, or if you are pregnant or breastfeeding.  Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below 8 years) may cause teeth staining (yellow-grey-brown). Consult your doctor if you experience any skin reactions, fever,  muscle, or joint problems.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Doxybuz 100 mg Injection:
Coadministration of Doxybuz 100 mg Injection with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Doxybuz 100 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doxybuz 100 mg Injection:
The combined use of cladribine with Doxybuz 100 mg Injection can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Doxybuz 100 mg Injection with Cladribine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Doxybuz 100 mg Injection:
Using Amisulpride together with Doxybuz 100 mg Injection can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Although taking Doxybuz 100 mg Injection and Amisulpride together can cause an interaction, it can be taken if a doctor has suggested it. If you're having any of these symptoms like an irregular heart rhythm, sudden dizziness, or severe diarrhea, it's important to contact the doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Doxybuz 100 mg Injection:
Taking Doxybuz 100 mg Injection with Ceritinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Ceritinib with Doxybuz 100 mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
How does the drug interact with Doxybuz 100 mg Injection:
Using chloroquine together with doxurubicin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Doxybuz 100 mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Doxybuz 100 mg Injection:
Taking Efavirenz and Doxybuz 100 mg Injection can increase the risk or severity of irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Doxybuz 100 mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Doxybuz 100 mg Injection:
The combined use of Doxybuz 100 mg Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Doxybuz 100 mg Injection and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Doxybuz 100 mg Injection:
Taking Doxybuz 100 mg Injection and clozapine may increase the risk of neutropenia.

How to manage the interaction:
Co-administration of Doxybuz 100 mg Injection with Clozapine can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - like a severe infection, fever, diarrhea, sore throat, muscle pain, or difficulty breathing - it's important to call your doctor right away." Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Doxybuz 100 mg Injection:
Using baricitinib together with Doxybuz 100 mg Injection may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Doxybuz 100 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Doxybuz 100 mg Injection:
Using Moxifloxacin together with Doxybuz 100 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Doxybuz 100 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, or irregular heartbeat, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Doxybuz 100 mg Injection to restore healthy bacteria in the intestine that may have been killed due to the usage of antibiotics. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Doxybuz 100 mg Injection.
  • Avoid intake of alcoholic beverages with Doxybuz 100 mg Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Doxybuz 100 mg Injection in fighting off infections.

Side Effects of Doxybuz 100 mg Injection

  • Pain, itching, swelling or redness at the site of injection
  • Nausea
  • Vomiting
  • Diarrhoea

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Doxybuz 100 mg Injection stops the growth of bacteria by preventing the synthesis of essential proteins necessary for their survival. Thereby, Doxybuz 100 mg Injection helps treat bacterial infections.

No, Doxybuz 100 mg Injection should not be stopped even if you feel better as it is an antibiotic medication and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form and will also become difficult to treat due to antibiotic resistance.

If you are taking Doxybuz 100 mg Injection, avoid taking antacids containing aluminium, calcium or magnesium or other drugs containing these cations; oral zinc, iron salts or bismuth preparations within 2 hours of consumption of Doxybuz 100 mg Injection as they may affect the absorption of Doxybuz 100 mg Injection. Avoid taking dairy products within 2 hours of taking Doxybuz 100 mg Injection as they may also impair the absorption of Doxybuz 100 mg Injection.

Use of Doxybuz 100 mg Injection during tooth development (last half of pregnancy, infancy, and in children below the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for pregnant women, breastfeeding mothers, and children below 8 years of age.

Doxybuz 100 mg Injection may make your skin sensitive to sunlight. So, apply sunscreen while going out and wear protective clothing and sunglasses. Avoid prolonged and unnecessary exposure to sunlight.

Doxybuz 100 mg Injection may lower the effectiveness of hormonal contraceptives such as birth control pills, rings, patches, or injections. Consult your doctor if you have any concerns, your doctor may advise regarding other forms of contraception.

Doxybuz 100 mg Injection does not completely prevent malaria caused by P. falciparum as Doxybuz 100 mg Injection is given as a prophylactic regimen (protection) whenever anyone enters a malaria-prone area.

Drug-Drug Interactions Checker List

  • ACITRETIN
  • ISOTRETINOIN
  • WARFARIN
  • DIGOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • ALUMINIUM
  • CALCIUM
  • MAGNESIUM
  • BISMUTH SUBSALICYLATE

Special Advise

  • Wear sunglasses and sunscreen when you go out in the sun as Doxybuz 100 mg Injection can make your skin sensitive to light.
  • Maintain a gap of 2 hours between Doxybuz 100 mg Injection and iron supplements and antacids as taking them together might affect the working of Doxybuz 100 mg Injection.
  • Doxybuz 100 mg Injection might affect certain lab tests, inform the person doing the tests that you are taking Doxybuz 100 mg Injection.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

Have a query?

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Alcohol

Caution

It is not known if alcohol affects Doxybuz 100 mg Injection. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Doxybuz 100 mg Injection belongs to pregnancy category D. There are no adequate and well-controlled studies on the use of Doxybuz 100 mg Injection in pregnant women. In some cases, taking Doxybuz 100 mg Injection during pregnancy may affect tooth and bone development in the unborn baby. So, if you are pregnant or planning for pregnancy contact the doctor before using Doxybuz 100 mg Injection.

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Breast Feeding

Caution

Doxybuz 100 mg Injection is excreted in the breast milk. However, the extent of absorption of Doxybuz 100 mg Injection by the breastfed infant is not known. Hence, the nursing mother should consult the doctor before using Doxybuz 100 mg Injection.

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Driving

Caution

It is not known if Doxybuz 100 mg Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Doxybuz 100 mg Injection is to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

At the recommended doses, Doxybuz 100 mg Injection is safe to use in patients with kidney disease if prescribed by a doctor.

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Children

Caution

Use of Doxybuz 100 mg Injection during tooth development in infants and children below 8 years of age may cause permanent staining of teeth (yellow-grey-brown). So, it is not recommended for children below 8 years of age.

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