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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Drotibest-M Tablet

Drotibest-M Tablet is a combination medicine used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

Drotibest-M Tablet is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Drotibest-M Tablet helps in relieving pain.

You are advised to take Drotibest-M Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Drotibest-M Tablet may cause dizziness, so drive with caution. Drotibest-M Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Drotibest-M Tablet

Pain relief

Directions for Use

Take Drotibest-M Tablet with food to prevent stomach upset. Swallow Drotibest-M Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Drotibest-M Tablet is a combination of two drugs, namely: Drotaverine and Mefenamic acid. Drotibest-M Tablet is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotibest-M Tablet helps in relieving pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Drotibest-M Tablet if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take Drotibest-M Tablet unless prescribed by the doctor, as Drotibest-M Tablet may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. Drotibest-M Tablet may cause dizziness, so drive only if you are alert. Drotibest-M Tablet should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking Drotibest-M Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Drotibest-M Tablet unless prescribed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Drotibest-M Tablet:
Coadministration of Drotibest-M Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Drotibest-M Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Drotibest-M Tablet:
Co-administration of Drotibest-M Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Drotibest-M Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
How does the drug interact with Drotibest-M Tablet:
The combined use of Drotibest-M Tablet and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Drotibest-M Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Drotibest-M Tablet:
Using Drotibest-M Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Drotibest-M Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Drotibest-M Tablet:
Drotibest-M Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Drotibest-M Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.
How does the drug interact with Drotibest-M Tablet:
Coadministration of Drotibest-M Tablet with Piroxicam can increase the risk side effects such as inflammation(swelling with redness and pain), bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Drotibest-M Tablet with Piroxicam together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Drotibest-M Tablet:
Taking Human immunoglobulin with Drotibest-M Tablet, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Drotibest-M Tablet, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Drotibest-M Tablet:
Taking Drotibest-M Tablet with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Fondaparinux with Drotibest-M Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding or bruising, feeling dizzy or lightheaded, dark or bloody stools, headache, weakness contact your doctor right away. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Drotibest-M Tablet:
Co-administration of Drotibest-M Tablet with Flurbiprofen can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Drotibest-M Tablet with Flurbiprofen together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, unusual bleeding or bruising, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Drotibest-M Tablet:
Coadministration of Drotibest-M Tablet with Methotrexate may increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between Drotibest-M Tablet and methotrexate, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), mouth sores or ulcers, infection, as well as flu-like symptoms(fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • WARFARIN
  • LEVODOPA
  • CYCLOSPORINE
  • TACROLIMUS
  • PROBENECID
  • DULOXETINE
  • LITHIUM
  • FLUOXETINE
  • SERTRALINE
  • DIGOXIN
  • METHOTREXATE
  • ZIDOVUDINE
  • MIFEPRESTONE

Disease/Condition Glossary

Pain: It is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and stomach ache. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

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