Drotin Plus Tablet 10's

Written By Divya L , PharmaD

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Prescription drug

MRP ₹209

(Inclusive of all Taxes)

₹31.4 Cashback (15%)

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About Drotin Plus Tablet

Drotin Plus Tablet belongs to the class of medicine called 'antispasmodic' combined with a painkiller, used to reduce and relieve abdominal pain and muscle spasms in the gastrointestinal tract, urinary tract and gall bladder. Abdominal (tummy) pain occurs between your chest and pelvic region (below the belly button and leg).

Drotin Plus Tablet is a combination of two drugs: Drotaverine (antispasmodic) and Paracetamol (pain killer). Drotaverine works by relieving contractions (spasms) associated with smooth muscles of the abdomen. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotin Plus Tablet helps in relieving abdominal pain and cramps.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Drotin Plus Tablet include dry mouth, feeling thirsty, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications, including other vitamins, before starting Drotin Plus Tablet . Inform your doctor if you have any liver, heart or kidney diseases and alcohol dependency before taking Drotin Plus Tablet . Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Drotin Plus Tablet . Drotin Plus Tablet may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Drotin Plus Tablet as it could lead to increased dizziness and risk of liver damage. Drotin Plus Tablet should not be given to children below one year of age as safety has not been established.

Uses of Drotin Plus Tablet

Abdominal pain and cramps.

Directions for Use

Swallow it as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Drotin Plus Tablet consists of Drotaverine (antispasmodic) and Paracetamol (pain killer). It relieves abdominal pain, and muscle spasms in the gastrointestinal tract, urinary tract and gall bladder. Drotaverine works by reducing contractions (spasms) associated with smooth muscles of the abdomen. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Drotin Plus Tablet helps in relieving abdominal pain and cramps.

Storage

Keep out of sight and reach of children.

Side effects of Drotin Plus Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Drug Warnings

Let your doctor know if you use any prescription and non-prescription medications, including other vitamins, before starting Drotin Plus Tablet . Inform your doctor if you have any liver, heart or kidney diseases and alcohol dependency. Drotin Plus Tablet may cause fluid retention (oedema); hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history. Do not take Drotin Plus Tablet if you are breastfeeding. Please consult your doctor know if you are pregnant and planning to conceive. Avoid consuming alcohol along with Drotin Plus Tablet as it could lead to increased dizziness and risk of liver damage. Drotin Plus Tablet is not recommended in children below one year of age.

Drug-Drug Interactions

ParacetamolOxazepam

Severe

ParacetamolValdecoxib

Severe

Drug-Drug Interactions

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ParacetamolOxazepam

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Drotin Plus Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Drotin Plus Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolValdecoxib

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Drotin Plus Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Drotin Plus Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.

ParacetamolLomitapide

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Lomitapide and Drotin Plus Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Drotin Plus Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

ParacetamolKetamine

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of ketamine and Drotin Plus Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Drotin Plus Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

ParacetamolTeriflunomide

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Teriflunomide with Drotin Plus Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Drotin Plus Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

ParacetamolLeflunomide

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Drotin Plus Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Drotin Plus Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

ParacetamolKetoconazole

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Drotin Plus Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Drotin Plus Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

ParacetamolMipomersen

Severe

How does the drug interact with Drotin Plus Tablet:
Co-administration of Mipomersen with Drotin Plus Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Drotin Plus Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
Massages can also be helpful.
Avoid freezing and hot temperatures.
Avoid wearing tight-fitting clothes, instead, wear loose garments.
Rest well, and get plenty of sleep.
To avoid developing pressure sores, change your position at least every two hours.
Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
Stay hydrated, drink plenty of water.

Side Effects of Drotin Plus Tablet

Dry mouth
Feeling thirsty
Dizziness
Nausea
Vomiting

Habit Forming

No

Therapeutic Class

ANTISPASMODICS/SPASMOLYTIC ANALGESICS

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Author Details

Written By

Divya L

PharmaD

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Drotin Plus Tablet work?

Drotin Plus Tablet is a combination of two drugs: Drotaverine and Paracetamol. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

Does Drotin Plus Tablet cause dizziness?

Drotin Plus Tablet may cause dizziness. So, drive only if you are alert and avoid driving or operating machinery if you feel dizzy.

Can I stop taking Drotin Plus Tablet if my symptoms are relieved?

Drotin Plus Tablet is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

Are there any specific contraindications while using Drotin Plus Tablet ?

Drotin Plus Tablet is to be carefully administered in patients with alcohol dependency or a history of kidney or liver damage. Please consult your doctor before starting Drotin Plus Tablet if you have a medical history.

Drug-Drug Interactions Checker List

WARFARIN
METOCLOPRAMIDE
DOMPERIDONE
CHOLESTYRAMINE
IMATINIB
LEVODOPA

Special Advise

Let your doctor know that you are taking Drotin Plus Tablet if you are undergoing any medical tests.
Monitor your blood pressure regularly since Drotaverine in Drotin Plus Tablet may lower your blood pressure.
Drotin Plus Tablet may cause fluid retention (oedema); hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.

Disease/Condition Glossary

Abdominal pain and cramps: Abdominal pain occurs between the chest and pelvic region, generally known as stomach or tummy pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. The common causes of abdominal pain include inflammation, infections, intestinal disorders and obstruction/blockage.