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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Matias Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dulamat-M 20 Capsule 10's

Dulamat-M 20 Capsule 10's belongs to the class of medications called ‘anticonvulsants’ used to treat neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Dulamat-M 20 Capsule 10's is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that works by increasing the levels of a chemical messenger (like serotonin and noradrenaline) in the brain required to regulate pain that travels through damaged nerves. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). 

Take this medicine as prescribed by your doctor. Dulamat-M 20 Capsule 10's may cause side-effects such as drowsiness, nausea, constipation, headache, dry mouth, increased sweating, anorexia (loss of appetite) and hot sensation (burning pain). Inform your doctor if any of these side-effects persist.

Do not take Dulamat-M 20 Capsule 10's if you are allergic to Duloxetine, Methylcobalamin, or any contents of it. Before taking Dulamat-M 20 Capsule 10's, inform your doctor if you have liver or kidney disease, seizures (fits), mania, bipolar disorder, glaucoma (an eye condition), bleeding disorders, or at risk of hyponatremia (low sodium levels, especially in patients taking diuretics or water pills). It is not recommended for use in children and young adults as it increases the risk of suicidal tendencies. Inform your doctor if you are pregnant or breastfeeding before using Dulamat-M 20 Capsule 10's. 

Uses of Dulamat-M 20 Capsule 10's

Neuropathic pain.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Dulamat-M 20 Capsule 10's is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine is a selective-serotonin reuptake (SSRI) inhibitor that increases serotonin levels and noradrenaline in the brain required for regulating pain through the damaged nerves. Methylcobalamin is a form of vitamin B12 that helps in rejuvenating and protecting damaged nerve cells by producing a substance called myelin (a protective layer of nerve cells). Together, Dulamat-M 20 Capsule 10's effectively treats neuropathic pain, improve nerve conduction for proper nerve signal functioning in the body. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Dulamat-M 20 Capsule 10's, inform your doctor if you have taken any antidepressants within the last 14 days or any medications used to treat infections. Please consult your doctor before stopping the medicine as it may cause withdrawal symptoms such as dizziness, tingling sensation, sleep disturbances, restlessness, nausea or vomiting, headache, or excessive sweating. So, do not abruptly stop taking medicine even if your symptoms improve. It may increase suicidal thoughts, so it is advised to use caution in patients with mania, bipolar disorder or depression. Prolonged use of Dulamat-M 20 Capsule 10's may decrease sodium level, affect blood pressure, and blood sugar level, so regular medical check-ups are required. Dulamat-M 20 Capsule 10's may increase your bleeding risk, and worsen your glaucoma condition. Hence, if you experience any eye problem or a bleeding problem, consult a doctor. 

Drug-Drug Interactions

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DuloxetinePhenelzine
Critical
DuloxetineSafinamide
Critical

Drug-Drug Interactions

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DuloxetinePhenelzine
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking phenelzine with Dulamat-M 20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dulamat-M 20 Capsule with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Coadministration of safinamide with Dulamat-M 20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Dulamat-M 20 Capsule is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineTranylcypromine
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking Tranylcypromine with Dulamat-M 20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Dulamat-M 20 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineLinezolid
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking Dulamat-M 20 Capsule with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Dulamat-M 20 Capsule with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Coadministration of metoclopramide with Dulamat-M 20 Capsule increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Dulamat-M 20 Capsule is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking Dulamat-M 20 Capsule with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Dulamat-M 20 Capsule and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineRasagiline
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking Rasagiline with Dulamat-M 20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Dulamat-M 20 Capsule is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Coadministration of eliglustat and Dulamat-M 20 Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dulamat-M 20 Capsule with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
DuloxetineProcarbazine
Critical
How does the drug interact with Dulamat-M 20 Capsule:
Taking Dulamat-M 20 Capsule with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dulamat-M 20 Capsule with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineRizatriptan
Severe
How does the drug interact with Dulamat-M 20 Capsule:
Taking Dulamat-M 20 Capsule with rizatriptan can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a possible interaction between Dulamat-M 20 Capsule and Rizatriptan, it can be taken if your doctor has advised it. If you notice any of these symptoms, like confusion, fever, excessive sweating, shivering, blurred vision, muscle spasms, shaking of hands and legs, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Dulamat-M 20 Capsule 10's Substitute

Substitutes safety advice
  • Dufree-M 20/1500 Capsule 10's

    by Others

    17.91per tablet
  • Dulorest-M Capsule 10's

    by Others

    28.90per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dulamat-M 20 Capsule 10's is a combination of two medicines: Duloxetine and Methylcobalamin. Duloxetine increases the number of neurotransmitters like serotonin and noradrenaline in the brain that can regulate pain. On the other hand, methylcobalamin (vitamin B12) can protect the nerve cells from further damage. Thus, Dulamat-M 20 Capsule 10's prevents nerve damage due to various conditions like injury or diabetic neuropathy and smooth conduction of nerve signal throughout the body.

Dulamat-M 20 Capsule 10's should be taken either in the morning or evening. If you feel drowsy after taking Dulamat-M 20 Capsule 10's, consider taking it in the evening. Also, it is recommended to take Dulamat-M 20 Capsule 10's every day at the same time for the best results.

Dulamat-M 20 Capsule 10's should not be used with antidepressants, especially antidepressants like monoamine oxidase (MAO) inhibitors (moclobemide, linezolid) as they cause serious side-effects. It is advised to wait at least 14 days after stopping MAO inhibitors before taking $namd also wait at least 5 days after stopping Dulamat-M 20 Capsule 10's before taking any MAO inhibitors.

Seek medical attention immediately if you notice any depressive thoughts while using Dulamat-M 20 Capsule 10's. Your doctor may change the dose or medicine to treat your condition.

Drug-Drug Interactions Checker List

  • MOCLOBEMIDE
  • PAROXETINE
  • FLUOXETINE
  • VENLAFAXINE
  • CLOMIPRAMINE
  • AMITRIPTYLINE
  • LINEZOLID
  • TRAMADOL
  • HYPERICUM PERFORATUM

Special Advise

  • Increased risk of suicidal thinking and behavioural change in children below 12 years, and young adults taking Dulamat-M 20 Capsule 10's for major depressive disorder (MDD) and other psychiatric disorders. Hence, the use of Dulamat-M 20 Capsule 10's is not approved for use in pediatric patients.  
  • If you experience small increases in fasting blood glucose, HbA1c, and total cholesterol (TC) levels, immediately contact a doctor. 
  • Regular blood pressure monitoring is required while using Dulamat-M 20 Capsule 10's. 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease, infection, or injury caused due to damaged sensory nerves. Pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. In normal condition, our body sends the pain signals when there is an injury, but in neuropathic pain, pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful). 

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