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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duoflo Combipack Kit

Duoflo Combipack Kit is a combination medicine indicated for the treatment of benign prostatic hypertrophy in men with an enlarged prostate. Duoflo Combipack Kit is used to treat men with moderate to severe voiding and storage symptoms of the lower urinary tract caused by BPH and bladder problems. Benign prostatic hyperplasia (BPH) is the non-cancerous enlargement of the prostate gland due to the multiplication of the cells. Benign prostatic hypertrophy/hyperplasia mostly occurs in older men. 
 
Duoflo Combipack Kit contains Solifenacin (anti-cholinergic) and Tamsulosin (alpha-blocker). Solifenacin reduces the undesirable contractions of the bladder, thereby increases the amount of urine that the bladder can hold. This decreases the urgency for urination. Tamsulosin relaxes the muscles of the bladder and prostate; this enables the urine to pass readily through the urethra, thereby makes it easier to pass urine. Together, Duoflo Combipack Kit helps in treating BPH.
 
You are advised to take Duoflo Combipack Kit for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, constipation, dizziness, indigestion, tiredness, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Duoflo Combipack Kit is intended for use in men only; women should not take Duoflo Combipack Kit. Duoflo Combipack Kit is not recommended for children. Duoflo Combipack Kit may cause dizziness, so drive with caution. Inform your doctor that you are taking Duoflo Combipack Kit if you are due to undergo cataract surgery. Avoid or limit alcohol consumption with Duoflo Combipack Kit as it could lead to increased dizziness. Keep your doctor informed about your health condition and medications before taking Duoflo Combipack Kit to rule out any side effects/interactions.

Uses of Duoflo Combipack Kit

Benign prostatic hyperplasia (enlarged prostate).

Directions for Use

Swallow Duoflo Combipack Kit as a whole with water; do not chew or break it.

Medicinal Benefits

Duoflo Combipack Kit is a combination of two drugs, namely: Solifenacin and Tamsulosin. Duoflo Combipack Kit is indicated for the treatment of benign prostatic hypertrophy in men with an enlarged prostate. Duoflo Combipack Kit is used to treat men with moderate to severe voiding and storage symptoms of the lower urinary tract caused by BPH and bladder problems. Solifenacin is an anticholinergic agent that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Tamsulosin is an alpha-blocker that relaxes the muscles of the bladder and prostate; this enables the urine to pass readily through the urethra, thereby making it easier to pass urine. Together, Duoflo Combipack Kit helps in treating benign prostatic hypertrophy.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Duoflo Combipack Kit if you are allergic to any of its components; if you have severe liver disease or kidney disease, are undergoing dialysis, have severe bowel or stomach condition, myasthenia gravis, glaucoma, and orthostatic hypotension. Inform your doctor if you have urinary retention, obstruction of the digestive system, heartburn, autonomic neuropathy, kidney or liver problems. Duoflo Combipack Kit is not recommended for women and children. Duoflo Combipack Kit may cause dizziness, so drive with caution. Avoid or limit alcohol consumption with Duoflo Combipack Kit as it could lead to increased dizziness. Rise slowly from a sitting/lying position as Duoflo Combipack Kit can cause orthostatic hypotension.

Drug-Drug Interactions

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SolifenacinMesoridazine
Critical

Drug-Drug Interactions

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How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Duoflo Combipack Kit with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
SolifenacinMesoridazine
Critical
How does the drug interact with Duoflo Combipack Kit:
Using Mesoridazine together with Duoflo Combipack Kit can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Duoflo Combipack Kit is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
How does the drug interact with Duoflo Combipack Kit:
The blood levels and effects of Duoflo Combipack Kit may be greatly increased when combined with itraconazole.

How to manage the interaction:
Duoflo Combipack Kit and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with atazanavir may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and atazanavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
TamsulosinFosamprenavir
Severe
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with fosamprenavir may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and fosamprenavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with ritonavir may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and ritonavir together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with Voriconazole may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and Voriconazole together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience dizziness, heart palpitation (irregular heartbeat). Do not stop using any medications without consulting doctor.
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with posaconazole may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and posaconazole together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience dizziness, lightheadedness, fainting, headache, and stuffy nose. Do not stop using any medications without consulting a doctor.
TamsulosinTelithromycin
Severe
How does the drug interact with Duoflo Combipack Kit:
Taking Duoflo Combipack Kit with telithromycin may significantly increase the blood levels and effects of Duoflo Combipack Kit.

How to manage the interaction:
Although taking Duoflo Combipack Kit and telithromycin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection unrelated to sexual activity). Do not stop using any medications without consulting doctor.
How does the drug interact with Duoflo Combipack Kit:
Duoflo Combipack Kit blood levels may rise when itraconazole and Duoflo Combipack Kit are administered together.

How to manage the interaction:
Itraconazole and Duoflo Combipack Kit may interact, but if a doctor prescribes them, you can still take them. If you develop dizziness, lightheadedness, fainting, headache, redness, nasal congestion, a racing heart, or priapism (prolonged and painful erection unrelated to sex), you should consult a doctor. Never stop taking any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Urinate as soon as you feel the urge.
  • Avoid excess caffeine and alcohol consumption.
  • Maintain a healthy diet and exercise regularly.
  • Practice kegel exercises to strengthen pelvic muscles.
  • Reduce stress levels by doing yoga or meditation. Nervousness can increase the frequency of urination.

Habit Forming

No

Therapeutic Class

BPH AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Duoflo Combipack Kit contains Solifenacin and Tamsulosin. Solifenacin reduces the undesirable contractions of the bladder, thereby increases the amount of urine that the bladder can hold. This decreases the urgency for urination. Tamsulosin relaxes the muscles of the bladder and prostate; this enables the urine to pass readily through the urethra, thereby makes it easier to pass urine. Together, Duoflo Combipack Kit helps in treating BPH.

If you have been scheduled or are undergoing cataract surgery, inform the doctor that you are taking Duoflo Combipack Kit. This will help the doctor to take appropriate measures regarding the medication and surgical techniques.

Orthostatic hypotension could be a side-effect of Duoflo Combipack Kit. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Prostatic carcinoma is the cancer of the prostate gland, whereas benign prostatic hyperplasia is the non-cancerous growth of the prostate. Prostatic carcinoma and benign prostatic hyperplasia may have the same symptoms. Therefore, people with benign prostatic hyperplasia should be examined prior to starting the treatment with Duoflo Combipack Kit to rule out the presence of carcinoma of the prostate.

Dry mouth could be a side effect of Duoflo Combipack Kit. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • NELFINAVIR
  • ERYTHROMYCIN
  • VERAPAMIL
  • DILTIAZEM
  • PAROXETINE
  • METOCLOPRAMIDE
  • CISAPRIDE

Disease/Condition Glossary

Benign prostatic hyperplasia: The prostate is a small, muscular gland in the male reproductive system which surrounds the urethra. Benign prostatic hyperplasia is the non-cancerous enlargement of the prostate gland due to the multiplication of the cells. Benign prostatic hypertrophy/hyperplasia mostly occurs in older men. This causes the prostate gland to swell, which leads to the squeezing of the urethra and limits the urine flow. The symptoms of benign prostatic hyperplasia include painful urination, difficulty in urination, excess urination, incomplete urination, leakage of urine, dribbling at the end of the urinary stream, and urgency in urination. An enlarged prostate is a normal condition of men ageing due to changes in male sex hormones.

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