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Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Duovir-E Kit Tablet

Duovir-E Kit Tablet belongs to the class of medications called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Duovir-E Kit Tablet is a combination of three medicines: Efavirenz, zidovudine, and lamivudine. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. Duovir-E Kit Tablet may cause side effects such as headache, tiredness, dizziness, drowsiness, vomiting, diarrhea, insomnia, nightmare, muscle damage, and anemia (low number of red blood cells). Inform your doctor if any of these side effects persist or get worse.

It is not recommended to take Duovir-E Kit Tablet if you are allergic to any contents of it. Before taking Duovir-E Kit Tablet, inform your doctor if you have any liver disease, hepatitis B or C (liver infections), a history of mental illness, or are seriously overweight and have kidney disease. Inform your doctor if you are pregnant or breastfeeding. Duovir-E Kit Tablet should not be given to children below 2 years of age. Duovir-E Kit Tablet should be used with caution in elderly patients. Alcohol consumption may increase the risk of side effects. Duovir-E Kit Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Duovir-E Kit Tablet

HIV infection

Directions for Use

Take Duovir-E Kit Tablet with food or after a meal as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Duovir-E Kit Tablet belongs to the group of medicines called antiretroviral therapy (ART). Duovir-E Kit Tablet contains efavirenz, zidovudine and lamivudine. These drugs belong to a group of medicines called nucleoside analogue reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection. It helps in improving the quality of life of a patient with HIV.

 

Storage

Keep Duovir-E Kit Tablet out of the sight and reach of children.
Side effects of Duovir-E Kit Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
  • Consume calcium-rich dairy products for bone health.
  • Eat green and leafy vegetables for essential nutrients.
  • Include lean protein sources like eggs and whole grains.
  • Use herbs and spices for added flavor and nutrition.
  • Choose fortified foods for extra nutritional benefits.
  • Get plenty of sleep for overall health and well-being.
Managing Medication-Triggered Pancreatitis: A Step-by-Step Guide:
  • If you take medication and get severe stomach pain, feel nauseous, vomit, or have a fever, get emergency medical help right away. This could be a sign of pancreatitis, an inflammation of the pancreas.
  • Your doctor may alter your treatment plan, provide supportive therapy, or prescribe alternative medications to manage the reaction. They will also perform regular tests to monitor your progress and adjust your treatment as needed.
  • Follow your doctor's advice, including dietary recommendations and lifestyle changes, and avoid triggers like alcohol and fatty foods.
  • Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.

Drug Warnings

Inform your doctor if you develop persistent diarrhea or vomiting, as it may affect the effectiveness of Duovir-E Kit Tablet. Duovir-E Kit Tablet may cause pancreatitis (inflammation of the pancreas), so inform your doctor if you develop symptoms such as nausea (feeling sick), vomiting, or stomach pain. Duovir-E Kit Tablet may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat), and tremors. Duovir-E Kit Tablet may destroy bone leading to symptoms such as joint stiffness or pain. It may also cause muscle pain, tenderness, or weakness. Duovir-E Kit Tablet may also cause dizziness and abnormal heartbeat. Inform your doctor immediately if you notice any significant changes in the electrocardiogram (ECG). Do not take Duovir-E Kit Tablet if you have severe liver disease, a slow heartbeat, or severe heart disease, a very low red blood cell count (anemia) or a very low white blood cell count (neutropenia). Speak with your doctor about the precautions to follow to avoid infecting other people as one can still pass on HIV while on this medicine, although the risk is somewhat lowered by antiretroviral therapy; it can spread through sexual contact with a person who already has the infection, or by transfer of infected blood. Duovir-E Kit Tablet does not cure HIV infection. Duovir-E Kit Tablet can make hormonal contraceptives less effective or less likely to work. So, use other effective methods for contraception, including a barrier form (cervical cap, condom, diaphragm, or contraceptive sponge) to prevent pregnancy while on Duovir-E Kit Tablet and for at least 12 weeks after stopping treatment as advised by your doctor. Do not breast-feed while taking this medicine. Also, do not take Duovir-E Kit Tablet with other medicines such as stavudine, used to treat HIV infection, ribavirin or ganciclovir to treat viral infections, rifampicin to treat bacterial infections, bepridil (used to treat heart disease), cisapride (used to treat heartburn), methadone (used to treat opiate addiction), St. John’s wort (Hypericum perforatum) (a herbal remedy used for depression and anxiety), flecainide, metoprolol (used to treat irregular heartbeat). Duovir-E Kit Tablet is not recommended in pregnancy as could harm the unborn baby or cause birth defects. You may need frequent medical tests while on Duovir-E Kit Tablet.

Drug-Drug Interactions

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EfavirenzBepridil
Critical
EfavirenzLomitapide
Critical

Drug-Drug Interactions

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EfavirenzBepridil
Critical
How does the drug interact with Duovir-E Kit Tablet:
Taking Bepridil with Duovir-E Kit Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Duovir-E Kit Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzLomitapide
Critical
How does the drug interact with Duovir-E Kit Tablet:
When Duovir-E Kit Tablet is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Duovir-E Kit Tablet with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Duovir-E Kit Tablet:
Taking Duovir-E Kit Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Duovir-E Kit Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Duovir-E Kit Tablet:
When Duovir-E Kit Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Duovir-E Kit Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duovir-E Kit Tablet:
Using carbamazepine together with Duovir-E Kit Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Duovir-E Kit Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Duovir-E Kit Tablet:
Taking Duovir-E Kit Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Duovir-E Kit Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duovir-E Kit Tablet:
When Duovir-E Kit Tablet is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Duovir-E Kit Tablet with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Duovir-E Kit Tablet:
When Duovir-E Kit Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Duovir-E Kit Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Duovir-E Kit Tablet:
Taking Duovir-E Kit Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Duovir-E Kit Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Duovir-E Kit Tablet:
Coadministration of Voriconazole with Duovir-E Kit Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Duovir-E Kit Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange and red vegetables, and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration. 
  • Wash your hands properly before and after eating.
  • Make sure you sleep at least 8 hours a day.

Side Effects of Duovir-E Kit Tablet

  • Headache
  • Nausea
  • Dizziness
  • Drowsiness
  • Vomiting
  • Diarrhea
  • Insomnia
  • Muscle damage
  • Anemia

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Duovir-E Kit Tablet is a combination of three medicines: Efavirenz, zidovudine, and lamivudine. These three drugs work by inhibiting the reverse transcriptase enzyme from working, which is required by the HIV-infected cells to make new viruses. Thereby preventing viral replication and controlling the infection.

Duovir-E Kit Tablet may cause side-effects such as abnormal dreams, difficulty concentrating, dizziness, blurred vision, whistling, ringing, aching muscles, difficulty in sleeping, hair loss, cough, feeling breathless. Inform your doctor if any of these side-effects persist or get worse.

Duovir-E Kit Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Duovir-E Kit Tablet may cause lactic acidosis (excess of lactic acid in the blood), a rare but a severe side effect, especially in women who are very obese. However, if you experience stomach pain, vomiting or nausea while taking Duovir-E Kit Tablet, please consult a doctor immediately.

No, Duovir-E Kit Tablet should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Duovir-E Kit Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Do not stop taking Duovir-E Kit Tablet without talking to your doctor. If you suddenly stop taking Duovir-E Kit Tablet, you may experience confusion, fever, mental state changes or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

Drug-Drug Interactions Checker List

  • DOXORUBICIN
  • RIBAVIRIN
  • STAVUDINE
  • CLADRIBINE
  • BEPRIDIL
  • CISAPRIDE
  • METHADONE
  • CLOMIPRAMINE
  • EMTRICITABINE

Special Advise

  • Duovir-E Kit Tablet may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Duovir-E Kit Tablet should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Duovir-E Kit Tablet. So, use necessary precautions to avoid infecting others.
  • Duovir-E Kit Tablet may cause abnormal liver function tests. So, regular monitoring of liver function is necessary while taking this medicine.

Disease/Condition Glossary

HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition and there is no definite cure for it.  However, it can be controlled by treating with antiretroviral agents.

Have a query?

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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

Duovir-E Kit Tablet should be used with caution in pregnant women. It is given only if clinically needed and when benefits outweigh the risk. It can harm the unborn baby or cause birth defects if taken during pregnancy.

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Breast Feeding

Caution

If Duovir-E Kit Tablet is prescribed during breastfeeding, the doctor may advise you to stop breastfeeding as this medicine can pass into breastmilk.

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Driving

Caution

Duovir-E Kit Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Duovir-E Kit Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Duovir-E Kit Tablet should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Duovir-E Kit Tablet is not recommended for use in children below 2 years. In children above 2 years of age, dose adjustments may be necessary.

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