Duovir Tablet 60's

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Reviewed By Sureshvarma D , MPharma

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60
₹1275.3
(₹21.26 per unit)
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10
₹193.95
(₹19.4 per unit)
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Whats That

About Duovir Tablet

Duovir Tablet belongs to the class of medicines called 'anti-retroviral agents', used for the treatment of immunodeficiency virus (HIV) infection. HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body.

Duovir Tablet contains lamivudine and zidovudine. Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Take Duovir Tablet as advised by your doctor. Duovir Tablet may cause common side effects like nausea, diarrhoea, headache, fatigue, cough, a feeling of discomfort, and nasal congestion (stuffy nose). Most of these side effects gradually resolve over time and do not require medical attention. However, if these side effects persist or worsen, please consult your doctor immediately.

Inform your doctor if you are allergic to any of the components in Duovir Tablet . Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, or pancreatic disease. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Uses of Duovir Tablet

Human immunodeficiency virus (HIV) infection.

Directions for Use

Swallow Duovir Tablet as a whole with a glass of water. Do not chew, crush or break it.

Medicinal Benefits

Duovir Tablet contains a combination of two medicines, namely: lamivudine and zidovudine, that belong to the group of medications called anti-retroviral agents. Duovir Tablet is primarily used for the treatment of human immunodeficiency virus (HIV) infection. Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Storage

keep Duovir Tablet out of sight and reach of children.

Side effects of Duovir Tablet

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Musculoskeletal Pain

Include omega-3 rich foods like fatty fish, ground flax, flaxseed oil, and walnuts.
Consume calcium-rich dairy products for bone health.
Eat green and leafy vegetables for essential nutrients.
Include lean protein sources like eggs and whole grains.
Use herbs and spices for added flavor and nutrition.
Choose fortified foods for extra nutritional benefits.
Get plenty of sleep for overall health and well-being.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Inflammation Of Pancreas

Managing Medication-Triggered Pancreatitis: A Step-by-Step Guide:

If you take medication and get severe stomach pain, feel nauseous, vomit, or have a fever, get emergency medical help right away. This could be a sign of pancreatitis, an inflammation of the pancreas.
Your doctor may alter your treatment plan, provide supportive therapy, or prescribe alternative medications to manage the reaction. They will also perform regular tests to monitor your progress and adjust your treatment as needed.
Follow your doctor's advice, including dietary recommendations and lifestyle changes, and avoid triggers like alcohol and fatty foods.
Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Nerve Damage Causing Weakness, Pain And Numbness In Limbs

If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
Use compression socks and make sure to rest for a while to get relief from pain.
Avoid smoking and intake of alcohol or fluids that aggravate the pain.
Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Drug Warnings

Inform your doctor if you are allergic to any of the components in Duovir Tablet . Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, pancreatic, or bone marrow suppression. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis, or opportunistic infections. Duovir Tablet may cause muscle disorders, especially when used for a long period. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately.

Drug-Drug Interactions

LamivudineEmtricitabine

Critical

LamivudineTeriflunomide

Severe

Drug-Drug Interactions

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LamivudineEmtricitabine

Critical

How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Duovir Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.

LamivudineTeriflunomide

Severe

How does the drug interact with Duovir Tablet:
Teriflunomide can cause Duovir Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.

LamivudineMipomersen

Severe

How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Duovir Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.

LamivudineBexarotene

Severe

How does the drug interact with Duovir Tablet:
Taking bexarotene together with Duovir Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.

LamivudineSorbitol

Severe

How does the drug interact with Duovir Tablet:
Duovir Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Duovir Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

LamivudineLomitapide

Severe

How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.

LamivudineZalcitabine

Severe

How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.

LamivudineLeflunomide

Severe

How does the drug interact with Duovir Tablet:
Combining Duovir Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.

ZidovudineCladribine

Severe

How does the drug interact with Duovir Tablet:
Combining Cladribine with Duovir Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Duovir Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

ZidovudineEtanercept

Severe

How does the drug interact with Duovir Tablet:
When Etanercept is used with Duovir Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etanercept with Duovir Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods

Mild

Drug-Food Interactions

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LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods

Mild

Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Consuming high-fat foods along with Duovir Tablet may decrease its effectiveness. Avoid or limit the consumption of high-fat foods with Duovir Tablet as it can increase the risk of side effects.

Diet & Lifestyle Advise

Take a diet high in vegetables, fruits, whole grains, and legumes.
Choose lean, low-fat sources of protein.
Limit sweets, soft drinks, and foods with added sugar.
Take proteins, carbohydrates, and a good little fat in all meals and snacks in your regular diet.
Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
Wash fruits and vegetables thoroughly.
Use a separate cutting board for raw meats.
Wash hands, utensils, and cutting boards with soap and water after each use.
Exercise regularly.
Avoid excessive alcohol and quit smoking.

Side Effects of Duovir Tablet

Nausea
Diarrhoea
Stomach pain
Loss of appetite
Tiredness
Lack of energy
Fever (high temperature)
Headache
Hair loss (alopecia)
Fatigue
Cough
Muscle pain and discomfort
Joint pain
Feeling of discomfort
Difficulty in sleeping (insomnia)
Irritated or runny nose

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Duovir Tablet work?

Duovir Tablet works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

In which conditions should I stay cautious while using Duovir Tablet ?

Duovir Tablet should be used with proper caution and doctor consultation if you have kidney disease, liver disease, pancreatic disease, low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Can I stop Duovir Tablet abruptly?

Stopping Duovir Tablet may increase the risk of treatment failure. So Duovir Tablet should not be stopped without consulting your doctor.

Can I use Duovir Tablet with other drugs?

Please consult your doctor if you are using other medicines before starting Duovir Tablet . However, medicines like didanosine, co-trimoxazole, clarithromycin, fluconazole, rifampicin, ranitidine, and phenytoin may interact with Duovir Tablet and should not be used simultaneously.

Drug-Drug Interactions Checker List

DIDANOSINE
EFAVIRENZ
ATOVAQUONE
CLARITHROMYCIN
GANCICLOVIR
COTRIMOXAZOLE
FLUCONAZOLE
RIFAMPICIN
PHENOBARBITAL
PHENYTOIN
VALPROIC ACID
RANITIDINE
CIMETIDINE
CLADRIBINE
PROBENECID
METHOTREXATE
ATORVASTATIN
FENOFIBRATE
CLOZAPINE

Special Advise

Skipping doses of Duovir Tablet may increase the risk of treatment failure. Make sure that you take all your doses at the correct time.
Always practice safe sex while taking Duovir Tablet . Do not share needles or personal items that can have blood or body fluids on them.
Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor because Duovir Tablet may cause the weakening of your bones.

Disease/Condition Glossary

HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. Symptoms include swollen lymph nodes, recurrent fevers, night sweats, fatigue, nausea, vomiting, diarrhoea, weight loss, skin rashes, recurrent oral or vaginal yeast infections, and pneumonia. The human immunodeficiency virus causes HIV infection. You can get HIV from contact with infected blood, semen, or vaginal fluids. Most people get the virus by having unprotected sex with someone who has HIV.