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Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Cipla Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Duovir Tablet 60's

Duovir Tablet 60's belongs to the class of medicines called 'anti-retroviral agents', used for the treatment of immunodeficiency virus (HIV) infection. HIV (human immunodeficiency virus) is a virus that attacks the body’s immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). This medicine is not a cure for HIV. It only prevents the virus from multiplying in your body.

Duovir Tablet 60's contains lamivudine and zidovudine. Duovir Tablet 60's works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Take Duovir Tablet 60's as advised by your doctor. Duovir Tablet 60's may cause common side effects like nausea, diarrhoea, headache, fatigue, cough, a feeling of discomfort, and nasal congestion (stuffy nose). Most of these side effects gradually resolve over time and do not require medical attention. However, if these side effects persist or worsen, please consult your doctor immediately.

Inform your doctor if you are allergic to any of the components in Duovir Tablet 60's. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, or pancreatic disease. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), or lactic acidosis.

Uses of Duovir Tablet 60's

Human immunodeficiency virus (HIV) infection.

Directions for Use

Swallow Duovir Tablet 60's as a whole with a glass of water. Do not chew, crush or break it.

Medicinal Benefits

Duovir Tablet 60's contains a combination of two medicines, namely: lamivudine and zidovudine, that belong to the group of medications called anti-retroviral agents. Duovir Tablet 60's is primarily used for the treatment of human immunodeficiency virus (HIV) infection. Duovir Tablet 60's works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Duovir Tablet 60's

  • Nausea
  • Diarrhoea
  • Stomach pain
  • Loss of appetite
  • Tiredness
  • Lack of energy
  • Fever (high temperature)
  • Headache
  • Hair loss (alopecia)
  • Fatigue
  • Cough
  • Muscle pain and discomfort
  • Joint pain
  • Feeling of discomfort
  • Difficulty in sleeping (insomnia)
  • Irritated or runny nose

Drug Warnings

Inform your doctor if you are allergic to any of the components in Duovir Tablet 60's. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Let your doctor know if you have kidney, liver, pancreatic, or bone marrow suppression. Please tell your doctor if you have a low red blood cell count (anaemia), low white blood cell count (neutropenia), osteonecrosis (death of bone tissue due to a lack of blood supply), lactic acidosis, or opportunistic infections. Duovir Tablet 60's may cause muscle disorders, especially when used for a long period. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
LamivudineBexarotene
Severe

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Duovir Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
LamivudineBexarotene
Severe
How does the drug interact with Duovir Tablet:
Taking bexarotene together with Duovir Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Duovir Tablet:
Duovir Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Duovir Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
LamivudineTeriflunomide
Severe
How does the drug interact with Duovir Tablet:
Teriflunomide can cause Duovir Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineZalcitabine
Severe
How does the drug interact with Duovir Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Duovir Tablet:
Combining Duovir Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Duovir Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineLomitapide
Severe
How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Duovir Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
LamivudineMipomersen
Severe
How does the drug interact with Duovir Tablet:
Taking Duovir Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Duovir Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
ZidovudineBaricitinib
Severe
How does the drug interact with Duovir Tablet:
coadministration of baricitinib and Duovir Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Duovir Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
ZidovudineInfliximab
Severe
How does the drug interact with Duovir Tablet:
When Duovir Tablet and Infliximab are taken together, the body breaks down Duovir Tablet faster. This can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Duovir Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods
Mild

Drug-Food Interactions

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LAMIVUDINE-150MG+ZIDOVUDINE-300MGHigh fat foods
Mild
Common Foods to Avoid:
Frozen Meals, Cheese, Red Meat, Potato Chips, Hamburgers, Hot Dogs, Ice Cream

How to manage the interaction:
Consuming high-fat foods along with Duovir Tablet may decrease its effectiveness. Avoid or limit the consumption of high-fat foods with Duovir Tablet as it can increase the risk of side effects.

Diet & Lifestyle Advise

  • Take a diet high in vegetables, fruits, whole grains, and legumes.
  • Choose lean, low-fat sources of protein.
  • Limit sweets, soft drinks, and foods with added sugar. 
  • Take proteins, carbohydrates, and a good little fat in all meals and snacks in your regular diet.
  • Avoid eating raw eggs, meats, or seafood (including sushi and oysters/shellfish).
  • Wash fruits and vegetables thoroughly.
  • Use a separate cutting board for raw meats.
  • Wash hands, utensils, and cutting boards with soap and water after each use.
  • Exercise regularly. 
  • Avoid excessive alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Duovir Tablet 60's Substitute

Substitutes safety advice
  • Lazid Tablet 60's

    by Others

    21.25per tablet
  • Duovir Tablet 10's

    by Others

    19.39per tablet
  • VIROCOMB FC 150MG TABLET

    by Others

    18.55per tablet
  • ZIDOVEX L TABLET

    by Others

    19.17per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • DIDANOSINE
  • EFAVIRENZ
  • ATOVAQUONE
  • CLARITHROMYCIN
  • GANCICLOVIR
  • COTRIMOXAZOLE
  • FLUCONAZOLE
  • RIFAMPICIN
  • PHENOBARBITAL
  • PHENYTOIN
  • VALPROIC ACID
  • RANITIDINE
  • CIMETIDINE
  • CLADRIBINE
  • PROBENECID
  • METHOTREXATE
  • ATORVASTATIN
  • FENOFIBRATE
  • CLOZAPINE

Special Advise

  • Skipping doses of Duovir Tablet 60's may increase the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Always practice safe sex while taking Duovir Tablet 60's. Do not share needles or personal items that can have blood or body fluids on them.
  • Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor because Duovir Tablet 60's may cause the weakening of your bones.

Disease/Condition Glossary

HIV (human immunodeficiency virus): HIV (human immunodeficiency virus) is a virus that attacks the body's immune system. If HIV is not treated, it can lead to AIDS (acquired immunodeficiency syndrome). There is currently no effective cure. Once people get HIV, they have it for life. But with proper medical care, HIV can be controlled. Symptoms include swollen lymph nodes, recurrent fevers, night sweats, fatigue, nausea, vomiting, diarrhoea, weight loss, skin rashes, recurrent oral or vaginal yeast infections, and pneumonia. The human immunodeficiency virus causes HIV infection. You can get HIV from contact with infected blood, semen, or vaginal fluids. Most people get the virus by having unprotected sex with someone who has HIV.

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