Duragain Tablet belongs to the group of medicines called selective serotonin reuptake inhibitors primarily used to treat premature ejaculation in adult men aged 18-64 years old. Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation before the man or his partner would like. This could lead to problems in a sexual relationship.

Duragain Tablet contains ‘Dapoxetine’, which increases the serotonin level in the nervous system; this increases the time it takes to ejaculate and improve the control over ejaculation. Thereby, helps in decreasing the worry or frustration about fast or premature ejaculation.

You are advised to take Duragain Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, headache, nausea, diarrhoea, dry mouth, and indigestion. Most of these side-effects do not require medical attention and will resolve gradually over time.  However, you are advised to talk to your doctor if you experience these side-effects persistently.

Duragain Tablet should not be used by men below 18years or above 65years. Duragain Tablet is not intended for use in women. Duragain Tablet may cause dizziness, sleepiness, fainting or blurred vision, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Duragain Tablet is not recommended for use in children below 18years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side-effects.

Duragain Tablet belongs to the group of medicines called selective serotonin reuptake inhibitors. Duragain Tablet is used to treat premature ejaculation in adult men aged 18-64years. Duragain Tablet works by increasing the serotonin level in the nervous system; this increases the time it takes to ejaculate and could improve control over ejaculation. Thereby, it helps in decreasing the worry or frustration about fast or premature ejaculation. 

• Dizziness
• Headache
• Nausea
• Diarrhoea
• Dry mouth
• Indigestion

Do not take Duragain Tablet if you are allergic to any of its contents; if you have heart problems such as heart failure or heart rhythm problems, mania or severe depression, moderate to severe liver problems, history of fainting, or if you are taking medicines such as monoamine oxidase inhibitors (MAOI), thioridazine, lithium, linezolid, tryptophan, tramadol, St. John’s wort, anti-depressants, and anti-migraine drugs. Inform your doctor if you have erectile dysfunction, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, or kidney problems. Duragain Tablet is not intended for use in women. Duragain Tablet may cause dizziness, sleepiness, fainting or blurred vision, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Duragain Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Rise slowly from sitting or lying position as Duragain Tablet may cause dizziness on standing up suddenly. Duragain Tablet should not be used by men below 18 years or above 65 years.

Drug-Drug Interactions: Duragain Tablet may interact with phenothiazine (thioridazine), anti-psychotic (lithium), antibiotic (linezolid, telithromycin, erythromycin, clarithromycin), an amino acid (tryptophan), pain killer (tramadol, ibuprofen, aspirin), anti-HIV (ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir, fosamprenavir), anti-fungal (ketoconazole, itraconazole, fluconazole), anti-depressant (nefazodone), blood thinner (warfarin), impotent agents (sildenafil, tadalafil, vardenafil), calcium channel blocker (diltiazem, verapamil), anti-emetics (aprepitant), BPH agents and anti-migraine medicines.

Drug-Food Interactions: Do not take St. John’s wort (herbal supplement used to treat depression) while taking Duragain Tablet. Avoid consuming grapefruit juice within 24 hours of taking Duragain Tablet as it could lead to an increase in the level of Duragain Tablet in the body. 

Drug-Disease Interactions: Inform your doctor if you have cardiovascular/heart disease, a history of dizziness due to low blood pressure, depression, mania, bipolar disorder, schizophrenia, epilepsy/fits, bleeding or blood clotting problems, glaucoma, kidney problems, or moderate to severe liver problems.

• THIORIDAZINE
• LITHIUM
• TRAMADOL
• ASPIRIN
• IBUPROFEN
• LINEZOLID
• CLARITHROMYCIN
• TELITHROMYCIN
• ERYTHROMYCIN
• TRYPTOPHAN
• RITONAVIR
• SAQUINAVIR
• NELFINAVIR
• ATAZANAVIR
• AMPRENAVIR
• FOSAMPRENAVIR
• KETOCONAZOLE
• ITRACONAZOLE
• FLUCONAZOLE
• NEFAZODONE
• WARFARIN
• SILDENAFIL
• TADALAFIL
• VARDENAFIL
• DILTIAZEM
• VERAMAPIL
• APREPITANT

• Maintaining a healthy weight, eating a balanced diet, and regular exercising may help manage premature ejaculation. 
• Pelvic floor exercises help in strengthening muscles.
• Decreasing the sensitivity of the penis by using condoms can be helpful.
• Share intimate time with your partner.
• Stay sexually active to prevent further problems.
• Eat foods that help improve blood flow, such as onions, garlic, bananas, chilli, eggs, omega-3 fatty acids, vitamin B1, and pepper.
• Exercise regularly as it helps in reducing stress.
• Avoid smoking and alcohol consumption.
• Get some sunlight; it helps increase melatonin, increasing sexual desire.
• Pay attention to your partner. Spend quality time. 

• Duragain Tablet has a bitter taste, so take Duragain Tablet with at least one full glass of water. This also helps in lowering the chance of fainting.
• Take Duragain Tablet 1-3hours before sexual activity. 
• Do not take more than 1tablet in a day (24hours).

Premature ejaculation: Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation before the man or his partner would like. This could lead to problems in a sexual relationship. Premature ejaculation is also known as rapid ejaculation, premature climax or early ejaculation. Symptoms include regular inability to delay the orgasm or ejaculation for more than a minute after the start of intercourse. Premature ejaculation may be lifelong/primary or acquired/secondary. Lifelong or primary premature ejaculation is when you experience this always or almost always since your first sexual experience. Acquired/secondary premature ejaculation is when you have had longer-lasting orgasms in your life but have developed early ejaculation. The causes of premature ejaculation could be poor self-esteem, depression, history of sexual abuse, worrying about ejaculation, anxiety about limited sexual experience, stress, dissatisfaction or problems in a relationship.