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  3. Dyfira 240 Capsule 60's

Dyfira 240 Capsule 60's, Pack of 1 Capsule
Dyfira 240 Capsule 60's, Pack of 1 Capsule
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Whats That

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Composition :

DIMETHYL FUMARATE-240MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dyfira 240 Capsule

Dyfira 240 Capsule belongs to the group of medications called Nrf2 activators used to treat people with the clinically isolated syndrome, relapsing-remitting forms, and secondary progressive types of multiple sclerosis. Multiple sclerosis is a condition in which the immune system attacks the protective covering of the nerves (myelin) and causes disrupted communication between the brain and body.

Dyfira 240 Capsule contains Dimethyl fumarate that stops the body's defence system from damaging the brain and spinal cord. Thereby, delaying the worsening of multiple sclerosis. It also reduces inflammation and avoids nerve damage, thus helping treat the symptoms of multiple sclerosis.

Take Dyfira 240 Capsule as prescribed. Dyfira 240 Capsule may cause certain common side effects including flushing, redness, itching, rash, nausea, vomiting, diarrhoea, stomach pain, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

If you are allergic or sensitive to any of the components of Dyfira 240 Capsule , you should notify your doctor. Inform your doctor before taking Dyfira 240 Capsule if you have a history of the lowered immune response, severe active infection, low white blood cell counts, and liver disorders. Avoid taking Dyfira 240 Capsule if you are pregnant or breastfeeding.

Uses of Dyfira 240 Capsule

Multiple sclerosis

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Dyfira 240 Capsule belongs to the group of medications called neuroprotective and anti-inflammatory agents, generally used to treat people with various forms of multiple sclerosis (MS). Dyfira 240 Capsule contains Dimethyl fumarate as an active ingredient. It works by reducing inflammation and avoiding nerve damage; thus, it effectively alleviates the symptoms of multiple sclerosis.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Dyfira 240 Capsule
  • Nourish your body with a balanced diet with protein-rich foods like fish, eggs, and beans. Fruits, vegetables, and nuts provide essential vitamins and minerals. If necessary, consider vitamin B12 and folate supplements.
  • Practice good hygiene to protect yourself from infections. Wash your hands often, stay up-to-date on vaccinations, avoid crowded areas, and take care when handling food, pets, and diapers.
  • Aim for a good night's sleep, targeting 8 hours of sleep. Find calm through stress-reducing practices like yoga, meditation, or deep breathing. Regular physical activity can also help.
  • Stay healthy by drinking plenty of water, eating probiotic-rich foods like yoghurt, and limiting processed foods and sugars. Consult your doctor, if you are having difficulties or concerns.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.

Drug Warnings

To treat your condition effectually, continue using Dyfira 240 Capsule for as long as your doctor has prescribed it. It is advisable to inform the doctor if you are allergic or sensitive to its components. Inform your doctor before taking Dyfira 240 Capsule if you have a history of the lowered immune response, severe active infection, low white blood cell counts, and liver disorders. Avoid taking Dyfira 240 Capsule if you are pregnant or breastfeeding. You must use effective contraception during treatment and for two months after stopping treatment. Keep your doctor informed about your health condition and all the medicines you are taking, including vaccinations to avoid drug interactions and side effects.

Drug-Drug Interactions

verifiedApollotooltip
Dimethyl fumarateBCG vaccine
Critical
Dimethyl fumarateCertolizumab
Severe

Drug-Drug Interactions

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Dimethyl fumarateBCG vaccine
Critical
How does the drug interact with Dyfira 240 Capsule:
Co-administration of BCG vaccine with Dyfira 240 Capsule can increase the risk of infection.

How to manage the interaction:
Taking Dyfira 240 Capsule with the BCG vaccine can possibly lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without a doctor's advice.
Dimethyl fumarateCertolizumab
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Certolizumab and Dyfira 240 Capsule may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Dyfira 240 Capsule with Certolizumab can possibly result in an interaction, but it can be taken if a doctor has advised it. These signs may include a swollen spleen or liver, stomach pain, ongoing fever, night sweats, and weight loss. If you experience any of these symptoms, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Dimethyl fumarateBaricitinib
Severe
How does the drug interact with Dyfira 240 Capsule:
Taking Dyfira 240 Capsule with Baricitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dyfira 240 Capsule can be taken with Baricitinib if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhea, sore throat, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
Dimethyl fumarateFingolimod
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Dyfira 240 Capsule with Fingolimod may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Dyfira 240 Capsule can be taken with Fingolimod if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhea, sore throat, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Dimethyl fumarateVoclosporin
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Dyfira 240 Capsule with Voclosporin can increase the risk of serious side effects.

How to manage the interaction:
Although there is a possible interaction between Dyfira 240 Capsule and Voclosporin, you can take these medicines together if prescribed by a doctor. Make sure to contact a doctor right away if you notice any signs of infection like fever, chills, or sore throat. Other symptoms to watch out for include diarrhea, muscle aches, difficulty breathing, weight loss, or pain while urinating. Do not discontinue any medications without consulting a doctor.
Dimethyl fumarateMipomersen
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Mipomersen and Dyfira 240 Capsule may significantly increase the risk of liver problems.

How to manage the interaction:
Although taking Dyfira 240 Capsule and Mipomersen together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Dimethyl fumarateLeflunomide
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Leflunomide with Dyfira 240 Capsule may increase the risk of serious infections. These medications may also lead to liver damage rarely.

How to manage the interaction:
Although there is a possible interaction, Dyfira 240 Capsule can be taken with Leflunomide if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of infection like muscle aches, shortness of breath, blood in phlegm, fever, chills, diarrhoea, sore throat, weight loss, red or inflamed skin, b1ody sores, pain or burning during urination. Seek immediate medical attention if you notice signs and symptoms of the liver such as fatigue, nausea, vomiting, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, and dark-coloured urine. Do not stop using any medications without talking to a doctor.
Dimethyl fumarateGolimumab
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Golimumab together with Dyfira 240 Capsule may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Dyfira 240 Capsule and Golimumab, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a serious infection, sepsis, complications, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
Dimethyl fumarateLomitapide
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Lomitapide and Diemthyl fumarate may increase the risk of infection.

How to manage the interaction:
Although taking Dyfira 240 Capsule and Lomitapide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, liver damage, or bleeding. Do not stop using any medications without talking to a doctor.
Dimethyl fumarateTeriflunomide
Severe
How does the drug interact with Dyfira 240 Capsule:
Co-administration of Teriflunomide and Dyfira 240 Capsule may significantly increase the risk of serious infections.

How to manage the interaction:
Although taking Dyfira 240 Capsule and Teriflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - liver damage, complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine or bleeding - please call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a well-balanced diet.
  • Exercising regularly helps in improving overall health. 
  • Meditation, music and yoga have also proven very effective in helping mental health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Avoid processed and fried food. 
  • Include leafy vegetables, poultry, seafood, beans, nuts, seeds, meat and fortified food in your diet.

Side Effects of Dyfira 240 Capsule

  • Flushing
  • Redness
  • Itching
  • Rash
  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach Pain
  • Indigestion

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Dyfira 240 Capsule Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:43 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
DIMETHYL FUMARATE-240MGBacterial infection of unspecified site
Moderate
DIMETHYL FUMARATE-240MGOther diseases of liver
Moderate

Drug-Diseases Interactions

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DIMETHYL FUMARATE-240MGBacterial infection of unspecified site
Moderate
How does the disease interact with Dyfira 240 Capsule:
individuals should be monitored for herpes zoster signs and symptoms while taking Dyfira 240 Capsule because serious herpes zoster instances have been reported in individuals receiving the medication. Dyfira 240 Capsule has also been linked to other severe opportunistic infections, such as bacterial, fungal, and viral infections.

How to manage the interaction:
Patients should be monitored for signs/symptoms of herpes zoster (shingles) while on Dyfira 240 Capsule as serious cases of herpes zoster have occurred in patients treated with Dyfira 240 Capsule. Withholding Dyfira 240 Capsule treatment in patients with herpes zoster or other serious infections until the infection has resolved should be considered.
DIMETHYL FUMARATE-240MGOther diseases of liver
Moderate
How does the disease interact with Dyfira 240 Capsule:
Although there is no need to change the dosage when taking Dyfira 240 Capsule in patients with liver disease, caution is advised because these patients have not been examined with the drug. Patients using Dyfira 240 Capsule in post-marketing situations have experienced clinically severe liver damage. Serum aminotransferase rises to more than five times the upper limit of normal (ULN) and elevation of total bilirubin to more than two times the ULN have also been noted as signs or symptoms of liver impairment; both abnormalities disappeared after the medication was stopped.

How to manage the interaction:
Caution is recommended when using Dyfira 240 Capsule in patients with liver problems.
DIMETHYL FUMARATE-240MGOther disorders of white blood cells
Moderate
How does the disease interact with Dyfira 240 Capsule:
Dyfira 240 Capsule usage may result in lower lymphocyte numbers. It is recommended use with caution while deciding whether or not to restart Dyfira 240 Capsule therapy for these patients.

How to manage the interaction:
The use of Dyfira 240 Capsule may decrease white blood cell counts. Withholding treatment in patients with serious infections and interruption of therapy in patients with low white blood cell count should be considered.
DIMETHYL FUMARATE-240MGMultiple sclerosis
Moderate
How does the disease interact with Dyfira 240 Capsule:
Patients with multiple sclerosis (MS) who were taking Dyfira 240 Capsule experienced progressive multifocal leukoencephalopathy (PML). PML is an opportunistic viral infection of the brain brought on by the John Cunningham virus (JC virus), and it typically results in death or severe disability. For patients with MS, caution and monitoring are advised. When a patient exhibits the first PML symptom or sign, Dyfira 240 Capsule should be discontinued and a proper diagnostic examination should be carried out.

How to manage the interaction:
Dyfira 240 Capsule should be withheld at the first sign/symptom suggestive of Progressive multifocal leukoencephalopathy (PML-a viral infection) and an appropriate diagnostic evaluation should be performed.
DIMETHYL FUMARATE-240MGAcute renal failure
Moderate
How does the disease interact with Dyfira 240 Capsule:
Although there is no need to change the dosage for patients with renal failure, caution is advised when taking Dyfira 240 Capsule in these individuals because it has not been tested in this population.

How to manage the interaction:
Caution is recommended when using Dyfira 240 Capsule in patients with kidney impairment.

FAQs

Dyfira 240 Capsule stops the body's defence system from damaging the brain and spinal cord. Thereby delaying the worsening of multiple sclerosis. It also reduces inflammation and avoids nerve damage, thus helping treat the symptoms of multiple sclerosis.

Even if you feel better, keep taking Dyfira 240 Capsule for as long as your doctor has prescribed it. Do not discontinue Dyfira 240 Capsule without first consulting your doctor.

There is currently no cure for multiple sclerosis, but several treatments can help control the condition. Dyfira 240 Capsule helps lower the number of relapses and slows down the progression of physical disabilities due to multiple sclerosis.

No, Dyfira 240 Capsule is a medication prescribed by a doctor to treat specific medical conditions such as multiple sclerosis. Taking it on your own can result in adverse effects.

Elevation of liver enzymes may occur in patients receiving Dyfira 240 Capsule . Your doctor may monitor transaminase and bilirubin levels while on treatment with Dyfira 240 Capsule .

Dyfira 240 Capsule may increase the risk of infections. It is advisable to obtain a complete blood count (CBC) before initiating treatment and monitor for infection during treatment and two months after discontinuation.

Drug-Drug Interactions Checker List

  • DIROXIMEL FUMARATE
  • FINGOLIMOD
  • ADALIMUMAB
  • BARICITINIB
  • CERTOLIZUMAB
  • ETANERCEPT
  • GOLIMUMAB
  • CLADRIBINE
  • FEXINIDAZOLE
  • BCG VACCINE
  • INFLUENZA (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)

Special Advise

  • Do not stop taking Dyfira 240 Capsule or adjust your dose without doctor notice.
  • Your doctor may advise complete blood count tests regularly.
  • Your doctor may also prescribe blood tests to check your liver function before, during, and after therapy.

Disease/Condition Glossary

Multiple sclerosis: Multiple sclerosis is a condition that affects the brain and spinal cord, resulting in symptoms such as problems with sensation, balance, vision, pain, impaired coordination, and fatigue. The immune system attacks the protective covering of the nerves (myelin) and causes disrupted communication between the brain and body due to nerve damage.

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