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About Dyranil 250mg/300mg Tablet

Dyranil 250mg/300mg Tablet belongs to a class of medication called 'antiprotozoals' used to treat diarrhea and amoebic dysentery. Diarrhea is characterized by loose, watery stools or a frequent need for bowel movement. Amoebic dysentery is an infection caused by any amoebae of the Entamoeba group. It causes intestinal inflammation, primarily of the colon. It can lead to mild or severe stomach cramps and severe diarrhea with mucus or blood in the faeces.

Dyranil 250mg/300mg Tablet is a combination of two medicines, namely: Diloxanide and Tinidazole. Diloxanide (amoebicide) works inside the large intestine to kill the infection-causing amoeba (parasites). Tinidazole (antibiotic) damages the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA essential for bacteria's survival. Thereby, it kills microorganisms and prevents the spread of infection.

You are advised to take Dyranil 250mg/300mg Tablet for as long as your doctor has prescribed it based on your medical condition. Swallow it as a whole with a glass of water. Do not chew, crush or break it. Dyranil 250mg/300mg Tablet is to be taken with food. You may experience common side effects like nausea, headache, dryness in the mouth, metallic taste, and flatulence in some cases. Most of these side effects of Dyranil 250mg/300mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Dyranil 250mg/300mg Tablet or any other medicines, please tell your doctor. Avoid taking Dyranil 250mg/300mg Tablet and consult a doctor before taking Dyranil 250mg/300mg Tablet, if you are pregnant or breastfeeding as it may harm the baby. Dyranil 250mg/300mg Tablet should be used with caution in kidney diseases, liver diseases, peripheral neuropathy, epilepsy, blood disorders, G-6 phosphate dehydrogenase deficiency, and sexually transmitted diseases.

Uses of Dyranil 250mg/300mg Tablet

Diarrhea and amoebic dysentery (amoebiasis).

Directions for Use

Dyranil 250mg/300mg Tablet should be taken in the dose and for the duration prescribed by your doctor. Swallow it as a whole with a glass of water. Do not chew, crush or break it. Dyranil 250mg/300mg Tablet is to be taken with food.

Medicinal Benefits

Dyranil 250mg/300mg Tablet is a combination of two medicines, namely: Diloxanide and Tinidazole belong to a class of medication called 'antiprotozoals' used to treat diarrhea and amoebic dysentery. Diloxanide (amoebicide) works inside the large intestine to kill the infection-causing amoeba (parasites). Tinidazole (antibiotic) works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA essential for bacteria's survival. Thereby, it kills micro-organisms and prevents the spread of infection. Dyranil 250mg/300mg Tablet is also used in the treatment of giardiasis (infection in your small intestine), trichomoniasis (a common sexually transmitted infection caused by a parasite), and appendicitis (inflammation of the appendix).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dyranil 250mg/300mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Stomach pain or cramps
  • Headache
  • Dizziness
  • Dryness in mouth
  • Metallic taste
  • Flatulence
  • Constipation

Drug Warnings

If you are allergic to Dyranil 250mg/300mg Tablet or any other medicines, please tell your doctor. Avoid taking Dyranil 250mg/300mg Tablet and consult a doctor before taking Dyranil 250mg/300mg Tablet, if you are pregnant or breastfeeding as it may harm the baby. Dyranil 250mg/300mg Tablet should be used with caution in kidney diseases, liver diseases, peripheral neuropathy, epilepsy, blood disorders, G-6 phosphate dehydrogenase deficiency, and sexually transmitted diseases. Dyranil 250mg/300mg Tablet with alcohol may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure. So please consult your doctor before taking Dyranil 250mg/300mg Tablet.

Drug-Drug Interactions

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TinidazoleAmprenavir
Critical

Drug-Drug Interactions

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TinidazoleAmprenavir
Critical
How does the drug interact with Dyranil 250mg/300mg Tablet:
Co-administration of Amprenavir and Dyranil 250mg/300mg Tablet can increase the risk or severity of developing serious side effects.

How to manage the interaction:
Co-administration of Amprenavir and Dyranil 250mg/300mg Tablet is generally avoided, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like flushing, severe headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, excessive sweating, dizziness, lightheadedness, blurred vision, or confusion. Rarely, more severe reactions may include unconsciousness or convulsions, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which leads to indigestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid the consumption of alcohol to treat your condition effectively.
  • Avoid using tobacco.
  • To cure your condition effectually, complete the full course of Dyranil 250mg/300mg Tablet even though you find symptomatic relief.

Habit Forming

No

Therapeutic Class

ANTIPROTOZOAL AGENTS, AMEBICIDES

Dyranil 250mg/300mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dyranil 250mg/300mg Tablet is a combination of two medicines, namely: Diloxanide and Tinidazole. Diloxanide (amoebicide) works inside the large intestine to kill the infection-causing amoeba (parasites). Tinidazole (antibiotic) works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA essential for bacteria's survival. Thereby, it kills microorganisms and prevents the spread of infection..

Dyranil 250mg/300mg Tablet causes common side effects like nausea, headache, dryness in the mouth, metallic taste, and flatulence in some cases. Most of these side effects of Dyranil 250mg/300mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Dyranil 250mg/300mg Tablet should be used with caution in kidney diseases, liver diseases, peripheral neuropathy, epilepsy, blood disorders, G-6 phosphate dehydrogenase deficiency, and sexually transmitted diseases.

Take Dyranil 250mg/300mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

Do not stop taking Dyranil 250mg/300mg Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Drug-Drug Interactions Checker List

  • DISULFIRAM
  • ALCOHOL
  • COTRIMOXAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • AMPICILLIN
  • DOXYCYCLINE
  • DILITAZEM
  • VERAMAPIL
  • AMPRENAVIR

Special Advise

  • It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
  • Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
  • Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache.

Disease/Condition Glossary

Amoebic dysentery (amoebiasis): Amebiasis is an intestinal (bowel) illness caused by a microscopic (tiny) parasite called Entamoeba histolytica, which is spread through human faeces (poop). Often there are no symptoms, but sometimes it causes diarrhea (loose stool/poop), nausea (a feeling of sickness in the stomach) and weight loss.

Diarrhea: Diarrhea is characterized by loose, watery stools or a frequent need for bowel movement. It usually lasts a few days and often disappears without any treatment. Symptoms include nausea, abdominal pain, cramping, bloating, and dehydration.

Giardiasis: Giardiasis is an infection in your small intestine. It’s caused by a microscopic parasite called Giardia lamblia. Giardiasis spreads through contact with infected people. And you can get giardiasis by eating contaminated food or drinking contaminated water. Symptoms include fatigue, nausea, diarrhea.

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