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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
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Consume Type :

ORAL

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Not Returnable

About Ediclar 125mg Oral Suspension

Ediclar 125mg Oral Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection. The affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Ediclar 125mg Oral Suspension is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms given to treat such kinds of conditions.

Ediclar 125mg Oral Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Ediclar 125mg Oral Suspension helps in the prevention of infections.

Ediclar 125mg Oral Suspension should only be if your doctor has prescribed you. Ediclar 125mg Oral Suspension should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Ediclar 125mg Oral Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolve after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Ediclar 125mg Oral Suspension if allergic to azithromycin, other macrolide antibiotics, or any components present in Ediclar 125mg Oral Suspension. Ediclar 125mg Oral Suspension isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of you taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Ediclar 125mg Oral Suspension. Before using the Ediclar 125mg Oral Suspension, tell your doctor if you ever had an allergy to Ediclar 125mg Oral Suspension have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Ediclar 125mg Oral Suspension as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Ediclar 125mg Oral Suspension

Bacterial infections

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Ediclar 125mg Oral Suspension in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

Ediclar 125mg Oral Suspension is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Ediclar 125mg Oral Suspension is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

Storage

Keep Ediclar 125mg Oral Suspension out of the sight and reach of children.
Side effects of Ediclar 125mg Oral Suspension
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Ediclar 125mg Oral Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Ediclar 125mg Oral Suspension and iron supplements and antacids. Besides this, in some cases, the use of Ediclar 125mg Oral Suspension causes antibiotic-associated diarrhoea. Ediclar 125mg Oral Suspension may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Ediclar 125mg Oral Suspension can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Ediclar 125mg Oral Suspension with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Ediclar 125mg Oral Suspension may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Drug-Drug Interactions

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ClarithromycinFlibanserin
Critical

Drug-Drug Interactions

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ClarithromycinFlibanserin
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Flibanserin is taken with Ediclar 125mg Oral Suspension, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
Combining Ediclar 125mg Oral Suspension with Pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Pimozide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
Co-administration of Ediclar 125mg Oral Suspension and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
When Regorafenib is taken with Ediclar 125mg Oral Suspension, may alter the blood levels and effects of Regorafenib.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Regorafenib can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinTerfenadine
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Terfenadine is taken with Ediclar 125mg Oral Suspension, the amount of Terfenadine in the blood can go up.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinLomitapide
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Lomitapide is taken with Ediclar 125mg Oral Suspension, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
When Nimodipine is taken with Ediclar 125mg Oral Suspension, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
When Methylergometrine is taken with Ediclar 125mg Oral Suspension, the amount of Methylergometrine in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ediclar 125mg Oral Suspension with Methylergometrine is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Ediclar 125mg Oral Suspension is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Ediclar 125mg Oral Suspension with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ediclar 125mg Oral Suspension:
Taking Silodosin with Ediclar 125mg Oral Suspension may significantly increase the blood levels and effects of Silodosin, this may cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Silodosin is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, or heart palpitation. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Ediclar 125mg Oral Suspension properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Ediclar 125mg Oral Suspension. 
  • Avoid intake of alcoholic beverages with Ediclar 125mg Oral Suspension as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Ediclar 125mg Oral Suspension in fighting off infections.

Side Effects of Ediclar 125mg Oral Suspension

  • Headache
  • Diarrhoea
  • Being sick (vomiting)
  • Nausea (feeling sick)
  • Loss of appetite
  • Taste change
  • Bloating
  • Indigestion
  • Abdominal pain
  • Insomnia (difficulty sleeping)

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Author Details

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Drug-Diseases Interactions

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CLARITHROMYCIN-125MG/5MLOther bacterial intestinal infections
Severe
CLARITHROMYCIN-125MG/5MLToxic liver disease
Moderate

Drug-Diseases Interactions

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CLARITHROMYCIN-125MG/5MLOther bacterial intestinal infections
Severe
How does the disease interact with Ediclar 125mg Oral Suspension:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.

How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-125MG/5MLToxic liver disease
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Patients on Ediclar 125mg Oral Suspension have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.

How to manage the interaction:
Caution and monitoring is advised if Ediclar 125mg Oral Suspension is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Ediclar 125mg Oral Suspension is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Ediclar 125mg Oral Suspension.
CLARITHROMYCIN-125MG/5MLOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
The kidney and liver are the organs that eliminate of Ediclar 125mg Oral Suspension the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.

How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-125MG/5MLMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.

How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-125MG/5MLAbnormal results of function studies
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Ediclar 125mg Oral Suspension and erythromycin.

How to manage the interaction:
Ediclar 125mg Oral Suspension should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.

FAQs

Ediclar 125mg Oral Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Ediclar 125mg Oral Suspension helps in the prevention of infections.

You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Ediclar 125mg Oral Suspension. Avoid taking any other antibiotics containing Ediclar 125mg Oral Suspension unless your doctor has prescribed you.

After taking antibiotics such as Ediclar 125mg Oral Suspension, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Ediclar 125mg Oral Suspension treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

No, Ediclar 125mg Oral Suspension is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.

Side-effects are rare with Ediclar 125mg Oral Suspension and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​

No, Ediclar 125mg Oral Suspension should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

Drug-Drug Interactions Checker List

  • AZITHROMYCIN
  • AMOXICILLIN+CLAVULANIC ACID
  • SIMVASTATIN
  • ATORVASTATIN
  • WARFARIN
  • BUDESONIDE+FORMOTEROL
  • CARBAMAZEPINE
  • PHENYTOIN
  • ERGOTAMINE
  • DIHYDROERGOTAMINE

Special Advise

  • Probiotics should be taken after taking the full course of Ediclar 125mg Oral Suspension in order to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

Have a query?

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Alcohol

Unsafe

Ediclar 125mg Oral Suspension should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Ediclar 125mg Oral Suspension should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Ediclar 125mg Oral Suspension; your doctor will decide whether Ediclar 125mg Oral Suspension can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Not enough scientific data available for Ediclar 125mg Oral Suspension, hence it is advised to consult your doctor.

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Liver

Caution

Ediclar 125mg Oral Suspension to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Ediclar 125mg Oral Suspension to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Ediclar 125mg Oral Suspension can be given safely to children in the form of suspension only, dose to be adjusted and recommended by a child specialist only.

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