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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
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Consume Type :

ORAL

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Not Returnable

About Ediclar 125mg Oral Suspension

Ediclar 125mg Oral Suspension belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection. The affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Ediclar 125mg Oral Suspension is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms given to treat such kinds of conditions.

Ediclar 125mg Oral Suspension contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Ediclar 125mg Oral Suspension helps in the prevention of infections.

Ediclar 125mg Oral Suspension should only be if your doctor has prescribed you. Ediclar 125mg Oral Suspension should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Ediclar 125mg Oral Suspension may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolve after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Ediclar 125mg Oral Suspension if allergic to azithromycin, other macrolide antibiotics, or any components present in Ediclar 125mg Oral Suspension. Ediclar 125mg Oral Suspension isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of you taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Ediclar 125mg Oral Suspension. Before using the Ediclar 125mg Oral Suspension, tell your doctor if you ever had an allergy to Ediclar 125mg Oral Suspension have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Ediclar 125mg Oral Suspension as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Ediclar 125mg Oral Suspension

Bacterial infections

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Ediclar 125mg Oral Suspension in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

Ediclar 125mg Oral Suspension is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Ediclar 125mg Oral Suspension is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ediclar 125mg Oral Suspension
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Ediclar 125mg Oral Suspension in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Ediclar 125mg Oral Suspension and iron supplements and antacids. Besides this, in some cases, the use of Ediclar 125mg Oral Suspension causes antibiotic-associated diarrhoea. Ediclar 125mg Oral Suspension may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Ediclar 125mg Oral Suspension can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Ediclar 125mg Oral Suspension with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Ediclar 125mg Oral Suspension may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Drug-Drug Interactions

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ClarithromycinTerfenadine
Critical
Critical

Drug-Drug Interactions

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ClarithromycinTerfenadine
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Terfenadine is taken with Ediclar 125mg Oral Suspension, the amount of Terfenadine in the blood can go up.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Quinidine is taken with Ediclar 125mg Oral Suspension, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
Using Lurasidone together with Ediclar 125mg Oral Suspension may result in significantly higher Lurasidone blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Ediclar 125mg Oral Suspension may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Naloxegol is taken with Ediclar 125mg Oral Suspension, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
When Dronedarone is taken with Ediclar 125mg Oral Suspension, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Ediclar 125mg Oral Suspension with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
Co-administration of Bepridil with Ediclar 125mg Oral Suspension may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ediclar 125mg Oral Suspension with Bepridil is not recommended as it can result in an interaction, it should be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ediclar 125mg Oral Suspension:
Taking Ediclar 125mg Oral Suspension with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Ediclar 125mg Oral Suspension:
Taking Ediclar 125mg Oral Suspension with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Ediclar 125mg Oral Suspension and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinErgotamine
Critical
How does the drug interact with Ediclar 125mg Oral Suspension:
When Ergotamine is taken with Ediclar 125mg Oral Suspension, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Ediclar 125mg Oral Suspension with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ediclar 125mg Oral Suspension:
The combination of Alprazolam and Ediclar 125mg Oral Suspension may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Alprazolam and Ediclar 125mg Oral Suspension, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Ediclar 125mg Oral Suspension properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Ediclar 125mg Oral Suspension. 
  • Avoid intake of alcoholic beverages with Ediclar 125mg Oral Suspension as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Ediclar 125mg Oral Suspension in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Author Details

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Drug-Diseases Interactions

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CLARITHROMYCIN-125MG/5MLOther bacterial intestinal infections
Severe
CLARITHROMYCIN-125MG/5MLToxic liver disease
Moderate

Drug-Diseases Interactions

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CLARITHROMYCIN-125MG/5MLOther bacterial intestinal infections
Severe
How does the disease interact with Ediclar 125mg Oral Suspension:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.

How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-125MG/5MLToxic liver disease
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Patients on Ediclar 125mg Oral Suspension have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.

How to manage the interaction:
Caution and monitoring is advised if Ediclar 125mg Oral Suspension is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Ediclar 125mg Oral Suspension is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Ediclar 125mg Oral Suspension.
CLARITHROMYCIN-125MG/5MLOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
The kidney and liver are the organs that eliminate of Ediclar 125mg Oral Suspension the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.

How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-125MG/5MLMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.

How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-125MG/5MLAbnormal results of function studies
Moderate
How does the disease interact with Ediclar 125mg Oral Suspension:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Ediclar 125mg Oral Suspension and erythromycin.

How to manage the interaction:
Ediclar 125mg Oral Suspension should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.

FAQs

Drug-Drug Interactions Checker List

  • AZITHROMYCIN
  • AMOXICILLIN+CLAVULANIC ACID
  • SIMVASTATIN
  • ATORVASTATIN
  • WARFARIN
  • BUDESONIDE+FORMOTEROL
  • CARBAMAZEPINE
  • PHENYTOIN
  • ERGOTAMINE
  • DIHYDROERGOTAMINE

Special Advise

  • Probiotics should be taken after taking the full course of Ediclar 125mg Oral Suspension in order to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

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