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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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ORAL

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Not Returnable

About Empraz L 75mg/40mg Tablet

Empraz L 75mg/40mg Tablet belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

Empraz L 75mg/40mg Tablet contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Empraz L 75mg/40mg Tablet helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

You are advised to take Empraz L 75mg/40mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Empraz L 75mg/40mg Tablet if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Empraz L 75mg/40mg Tablet may increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Empraz L 75mg/40mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Empraz L 75mg/40mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Empraz L 75mg/40mg Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Empraz L 75mg/40mg Tablet

Gastro-oesophageal reflux disease.

Directions for Use

Take Empraz L 75mg/40mg Tablet 1hour prior food. Swallow Empraz L 75mg/40mg Tablet as a whole with a glass of water, do not chew, or crush it.

Medicinal Benefits

Empraz L 75mg/40mg Tablet belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Empraz L 75mg/40mg Tablet is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Empraz L 75mg/40mg Tablet helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Empraz L 75mg/40mg Tablet if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Empraz L 75mg/40mg Tablet if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Empraz L 75mg/40mg Tablet may increase the risk of bone fractures. Do not take Empraz L 75mg/40mg Tablet if you are pregnant or breastfeeding. Empraz L 75mg/40mg Tablet may cause dizziness and drowsiness, so drive only if you are alert. Empraz L 75mg/40mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Empraz L 75mg/40mg Tablet as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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FAQs

Empraz L 75mg/40mg Tablet is a combination of two drugs, namely: Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Empraz L 75mg/40mg Tablet helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side-effect of Empraz L 75mg/40mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Empraz L 75mg/40mg Tablet with nelfinavir (a drug used to treat HIV infections). Consult your doctor before taking Empraz L 75mg/40mg Tablet with other medicines to rule out unpleasant side-effects.

Empraz L 75mg/40mg Tablet contains esomeprazole which might increase the risk of fracture in the wrist, hip or spine. This mainly occurs in people taking Empraz L 75mg/40mg Tablet for longer durations. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, your doctor may prescribe calcium and vitamin D supplements.

Empraz L 75mg/40mg Tablet may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Empraz L 75mg/40mg Tablet.

Dry mouth could be a side-effect of Empraz L 75mg/40mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • ATAZANAVIR
  • CLOPIDOGREL
  • WARFARIN
  • CILOSTAZOL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • ERLOTINIB
  • METHOTREXATE
  • CITALOPRAM
  • IMIPRAMINE
  • CLOMIPRAMINE
  • DULOXETINE
  • DIAZEPAM
  • PHENYTOIN
  • CISAPRIDE
  • DIGOXIN
  • TACROLIMUS
  • RIFAMPICIN

Special Advise

  • Empraz L 75mg/40mg Tablet may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Empraz L 75mg/40mg Tablet.
  • Inform your doctor before taking Empraz L 75mg/40mg Tablet if you are due to have Chromogranin A test.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

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