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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ENACE D 10MG TABLET

ENACE D 10MG TABLET belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

ENACE D 10MG TABLET is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take ENACE D 10MG TABLET as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of ENACE D 10MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

ENACE D 10MG TABLET is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking ENACE D 10MG TABLET. Avoid potassium supplements with ENACE D 10MG TABLET as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking ENACE D 10MG TABLET.

Uses of ENACE D 10MG TABLET

Hypertension (high blood pressure)

Directions for Use

Take ENACE D 10MG TABLET with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

ENACE D 10MG TABLET is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to ENACE D 10MG TABLET or any other medicines, please tell your doctor. ENACE D 10MG TABLET is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking ENACE D 10MG TABLET. It is advised to complete the full course of medication and do not suddenly stop taking ENACE D 10MG TABLET as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with ENACE D 10MG TABLET as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking ENACE D 10MG TABLET. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking ENACE D 10MG TABLET. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Enace D 10mg Tablet 30s:
Using aliskiren together with Enace D 10mg Tablet 30s may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enace D 10mg Tablet 30s with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Taking Cisapride and Enace D 10mg Tablet 30s can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Enace D 10mg Tablet 30s together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Enace D 10mg Tablet 30s:
Taking Dofetilide and Enace D 10mg Tablet 30s can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Enace D 10mg Tablet 30s together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Combine use of Enace D 10mg Tablet 30s and Valsartan can increase the effect of Valsartan.

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s together with Valsartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat, contact a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Using Enace D 10mg Tablet 30s together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Enace D 10mg Tablet 30s together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Coadministration of Ketoconazole and Enace D 10mg Tablet 30s may increase the risk of liver problems.

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s with Ketoconazole may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience fever, dark-coloured urine, light-coloured stools, yellowish discolouration of skin and eyes, and abdominal pain. Do not discontinue any medications without consulting a doctor.
EnalaprilPotassium acetate
Severe
How does the drug interact with Enace D 10mg Tablet 30s:
Combining Enace D 10mg Tablet 30s and Potassium acetate may result in significantly higher blood potassium levels. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscle paralysis, abnormal heart rhythm

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s and Potassium acetate together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience nausea, vomiting, weakness, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without a doctor's advice.
How does the drug interact with Enace D 10mg Tablet 30s:
Due to additive or synergistic effects, coadministration of Enace D 10mg Tablet 30s with Irbesartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. In severe cases, hyperkalemia can lead to muscle paralysis,kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s together with Irbesartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Enace D 10mg Tablet 30s has the potential to cause liver damage; this effect can be increased by the coadministration of medications that affect the liver, such as Leflunomide. This effect can be seen even long after discontinuing leflunomide as it stays in your blood longer.

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s together with Leflunomide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of liver damage like fever, chills, unusual bleeding, dark-coloured urine, light colour stools, yellowish discolouration of skin and eyes, and abdominal pain. It is advised not to consume alcohol while using these medications as it may increase the damage o the liver. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Enace D 10mg Tablet 30s:
Enace D 10mg Tablet 30s combined with Trimethoprim can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enace D 10mg Tablet 30s together with Trimethoprim may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-10MG+HYDROCHLOROTHIAZIDE-25MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of potassium rich food while on the treatment with Enace D 10mg Tablet 30s can lead to weakness, confusion, numbness of tingling sensation in hands or legs, or slow or rapid heartbeat. Avoid or limit consumption of potassium rich food while on the treatment with Enace D 10mg Tablet 30s.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ENACE D 10MG TABLET contains Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

You are not recommended to take furosemide with ENACE D 10MG TABLET as co-administration of these two medicines may increase the risk of low blood pressure. However, if you experience dizziness, reduced heart rate, headache or fainting, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

It is advised to inform your doctor if you have had skin cancer or develop an unexpected skin lesion as hydrochlorothiazide in ENACE D 10MG TABLET may increase the risk of certain types of skin and lip cancer especially when taken in high doses for a long period. Therefore, it is recommended to protect the skin from UV rays and sun exposure while taking ENACE D 10MG TABLET.

No, you are not recommended to take potassium supplements with ENACE D 10MG TABLET as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines with ENACE D 10MG TABLET.

If you have any kidney problems, it is advised to inform your doctor before taking ENACE D 10MG TABLET as ENACE D 10MG TABLET may worsen kidney functioning if there is any existing kidney problem. However, if you experience unexplained weight gain, swelling in feet, ankles or hands, please consult your doctor immediately.

You are not recommended to take more than the prescribed dose of ENACE D 10MG TABLET as it may cause ENACE D 10MG TABLET overdose resulting in symptoms such as low blood pressure, cough, nausea, dizziness, cramps, drowsiness, fast or slow heartbeat, anxiety, increased urination or difficulty in urination. However, if you experience any of these symptoms while taking ENACE D 10MG TABLET, please consult a doctor immediately.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • PREGABALIN
  • METOPROLOL
  • AMLODIPINE
  • ALBUTEROL
  • SALMETEROL
  • CHOLECALCIFEROL

Special Advise

  • Regular monitoring of blood pressure, kidney functioning, and amount of electrolytes such as sodium, potassium, magnesium, creatinine, and liver enzyme levels are recommended while taking ENACE D 10MG TABLET.
  • If you are about to take an anti-doping test, please inform your doctor that you are taking ENACE D 10MG TABLET as it may give a positive result.
  • Low salt diet and regular exercise are recommended along with ENACE D 10MG TABLET for effective results.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. 

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