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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer

Nicholas Piramal India Limited

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Enace D 5 Tablet 30's

Enace D 5 Tablet 30's belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.

Enace D 5 Tablet 30's is a combination of two drugs: Enalapril (angiotensin-converting enzyme inhibitor) and Hydrochlorothiazide (diuretic). Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body that causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide belongs to diuretics (water tablets) that work by increasing the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Take Enace D 5 Tablet 30's as prescribed. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhoea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of Enace D 5 Tablet 30's do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Enace D 5 Tablet 30's is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enace D 5 Tablet 30's. Avoid potassium supplements with Enace D 5 Tablet 30's as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enace D 5 Tablet 30's.

Uses of Enace D 5 Tablet 30's

Hypertension (high blood pressure)

Directions for Use

Take Enace D 5 Tablet 30's with or without food as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Enace D 5 Tablet 30's is a combination of two drugs, namely: Enalapril and Hydrochlorothiazide. Enalapril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme which decreases the production of angiotensin II in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Hydrochlorothiazide is a diuretic (water tablet) that increases the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Thus, together they lower high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enace D 5 Tablet 30's

  • Dizziness
  • Weakness
  • Blurred vision
  • Nausea
  • Headache
  • Orthostatic hypotension (low blood pressure when standing up from lying or sitting position)
  • High cholesterol or uric acid levels
  • Electrolyte imbalance
  • Diarrhoea
  • Chest pain
  • Fast heartbeat
  • Changes in taste
  • Stomach pain

Drug Warnings

If you are known to be allergic to Enace D 5 Tablet 30's or any other medicines, please tell your doctor. Enace D 5 Tablet 30's is not recommended for pregnant women, especially in second and third trimesters as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Enace D 5 Tablet 30's. It is advised to complete the full course of medication and do not suddenly stop taking Enace D 5 Tablet 30's as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with Enace D 5 Tablet 30's as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking Enace D 5 Tablet 30's. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking Enace D 5 Tablet 30's. 

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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EnalaprilAliskiren
Critical
How does the drug interact with Enace D 5 Tablet:
Using aliskiren together with Enace D 5 Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enace D 5 Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Enace D 5 Tablet:
Taking Cisapride and Enace D 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Enace D 5 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Enace D 5 Tablet:
Taking Dofetilide and Enace D 5 Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Enace D 5 Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Enace D 5 Tablet:
Taking potassium citrate with Enace D 5 Tablet may increase potassium levels in the blood, leading to kidney problems, muscle paralysis, and abnormal heart rhythm.

How to manage the interaction:
Co-administration of Enace D 5 Tablet with Potassium citrate can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medications without a doctor's advice.
EnalaprilOlmesartan medoxomil
Severe
How does the drug interact with Enace D 5 Tablet:
Coadministration of Olmesartan medoxomil with Enace D 5 Tablet can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking olmesartan medoxomil together with Enace D 5 Tablet may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilTelmisartan
Severe
How does the drug interact with Enace D 5 Tablet:
Coadministration of Enace D 5 Tablet with Telmisartan may increase the risk of hyperkalemia (high potassium levels in the blood), hypotension, syncope (fainting), and renal failure due to additive or synergistic effects. If you are elderly, dehydrated, or have a history of renal or heart illness, your risk is enhanced.

How to manage the interaction:
Although taking Enace D 5 Tablet together with Telmisartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, papayas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilTrimethoprim
Severe
How does the drug interact with Enace D 5 Tablet:
Enace D 5 Tablet combined with Trimethoprim can cause hyperkalemia by elevating blood potassium levels. In severe cases, hyperkalemia can induce muscle paralysis, renal damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of renal or cardiovascular disease.

How to manage the interaction:
Although taking Enace D 5 Tablet together with Trimethoprim may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
EnalaprilTriamterene
Severe
How does the drug interact with Enace D 5 Tablet:
Taking Enace D 5 Tablet together with triamterene may increase the levels of potassium in your blood (hyperkalemia), especially if you are dehydrated or have kidney disease or diabetes.

How to manage the interaction:
Although taking Enace D 5 Tablet with Triamterene may result in an interaction, they can be taken together if your doctor prescribes it. However, contact your doctor immediately if you experience weakness, confusion, numbness or tingling. Do not discontinue any medication without consulting your doctor.
EnalaprilLomitapide
Severe
How does the drug interact with Enace D 5 Tablet:
Combining lipitapide with other drugs that can damage the liver, including Enace D 5 Tablet, increases the risk of liver issues.

How to manage the interaction:
Although taking Enace D 5 Tablet and Lomitapide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - joint pain, swelling, skin rash, itching, abdominal pain, or dark urine - immediately contact your doctor. Do not stop using any medications without a doctor's advice.
EnalaprilTelmisartan
Severe
How does the drug interact with Enace D 5 Tablet:
Co-administration of Enace D 5 Tablet with Telmisartan can increase the risk of kidney failure, low blood pressure, and high potassium levels.

How to manage the interaction:
Although there is a possible interaction between Enace D 5 Tablet and Telmisartan, you can take these medicines together if prescribed by your doctor. However, contact a doctor if you experience nausea, vomiting, weakness, tingling of the hands and feet, or feelings of heaviness in the legs, so it's important to seek medical help. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ENALAPRIL-5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consumption of potassium rich food while on the treatment with Enace D 5 Tablet can lead to weakness, confusion, numbness of tingling sensation in hands or legs, or slow or rapid heartbeat. Avoid or limit consumption of potassium rich food while on the treatment with Enace D 5 Tablet.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavor to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing, or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in vegetables, fruits, whole grains, and low-fat dairy products.
  • Try to include heart-healthy omega 3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil which may help in lowering high blood pressure.
  • Quit smoking and avoid the consumption of alcohol.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Enace D 5 Tablet 30's Substitute

Substitutes safety advice
  • Envas-H Tablet 10's

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    10.26per tablet
  • ENACE D 5MG TABLET 30'S

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    7.25per tablet
  • Enal-H Tablet 10's

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    2.66per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE
  • HYDROCHLOROTHIAZIDE
  • FUROSEMIDE
  • PREGABALIN
  • METOPROLOL
  • AMLODIPINE
  • ALBUTEROL
  • SALMETEROL
  • CHOLECALCIFEROL

Special Advise

  • Regular monitoring of blood pressure, kidney functioning, and amount of electrolytes such as sodium, potassium, magnesium, creatinine, and liver enzyme levels are recommended while taking Enace D 5 Tablet 30's.
  • If you are about to take an anti-doping test, please inform your doctor that you are taking Enace D 5 Tablet 30's as it may give a positive result.
  • Low salt diet and regular exercise are recommended along with Enace D 5 Tablet 30's for effective results.

Disease/Condition Glossary

Hypertension: Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. 

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