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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About ENBREL 25MG INJECTION

ENBREL 25MG INJECTION is an immunosuppressant medicine that helps reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis. ENBREL 25MG INJECTION is generally used alone or in combination with methotrexate medicine.

ENBREL 25MG INJECTION consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

ENBREL 25MG INJECTION may cause certain side effects such as tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problem, redness on the skin and arms, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. ENBREL 25MG INJECTION is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. ENBREL 25MG INJECTION may cause dizziness, so drive only if you are alert and focused. ENBREL 25MG INJECTION should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of liver damage. ENBREL 25MG INJECTION is not recommended for use in pregnant and nursing mothers as it can cause serious adverse effects on the baby.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ETANERCEPT-25MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of ENBREL 25MG INJECTION

Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis.

Medicinal Benefits

ENBREL 25MG INJECTION consists of Etanercept, which belongs to TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and other autoimmune disorders.

Side Effects of ENBREL 25MG INJECTION

  • Tingling or numbness
  • Dizziness
  • Shortness of breath
  • Bleeding
  • Bruising
  • Vision problem
  • Redness on the skin and arms
  • Injection site reactions

Directions for Use

ENBREL 25MG INJECTION will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), and diabetes as it can worsen your health condition. Do not take live vaccines while being treated with ENBREL 25MG INJECTION to prevent any serious consequences. ENBREL 25MG INJECTION may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of stomach bleeding/ulcers. ENBREL 25MG INJECTION is not recommended for use in children below two years of age as safety and efficacy is not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Therapeutic Class

IMMUNOSUPPRESSANTS

Drug-Drug Interactions

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EtanerceptSirolimus
Severe
EtanerceptCiclosporin
Severe

Drug-Drug Interactions

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EtanerceptSirolimus
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Coadministration of ENBREL 25MG INJECTION with Sirolimus, may increase the risk or severity of developing serious infection.

How to manage the interaction:
Although there is a possible interaction between Sirolimus and ENBREL 25MG INJECTION, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptCiclosporin
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking ENBREL 25MG INJECTION and ciclosporin together can result in an interaction, it can be taken if a doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
EtanerceptAldesleukin
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Taking ENBREL 25MG INJECTION with Aldesleukin may increase the risk or severity of infection.

How to manage the interaction:
Co-administration of ENBREL 25MG INJECTION with Aldesleukin can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptDexamethasone
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Dexamethasone, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between ENBREL 25MG INJECTION and Dexamethasone, you can take these medicines together if prescribed by a doctor. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptPrednisolone
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Prednisolone, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between ENBREL 25MG INJECTION and Prednisolone, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptZidovudine
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with zidovudine, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking ENBREL 25MG INJECTION with Zidovudine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptGanciclovir
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Using ganciclovir together with ENBREL 25MG INJECTION may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Ganciclovir and ENBREL 25MG INJECTION, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.
EtanerceptCapecitabine
Severe
How does the drug interact with ENBREL 25MG INJECTION:
Co-administration of ENBREL 25MG INJECTION with Capecitabine may increase the risk or severity of infection may increase.

How to manage the interaction:
Co-administration of ENBREL 25MG INJECTION with Capecitabine can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptIrinotecan
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Irinotecan, the risk or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between ENBREL 25MG INJECTION and Irinotecan, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtanerceptPonatinib
Severe
How does the drug interact with ENBREL 25MG INJECTION:
When ENBREL 25MG INJECTION is used with Ponatinib, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between ENBREL 25MG INJECTION and Ponatinib, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CERTOLIZUMAB
  • INFLIXIMAB
  • ADALIMUMAB
  • ANAKINRA
  • WARFARIN
  • SIMVASTATIN
  • OMEPRAZOLE
  • DEXTROMETHORPHAN
  • ATORVASTATIN
  • CYCLOPHOSPHAMIDE

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Special Advise

  • It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment though the patient gets a negative tuberculin test.
  • It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting ENBREL 25MG INJECTION.

Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that causes joint pain and damage. It occurs when the immune system does not work properly. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis symptoms include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

Psoriatic arthritis: It is a type of inflammatory arthritis which occurs in patients with psoriasis. It could also occur in patients without psoriasis, particularly in those with a family history of psoriasis. It affects large joints in the lower extremities, the distal joints of toes and fingers, and the back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

ENBREL 25MG INJECTION Substitute

Substitutes safety advice
  • Intacept 25 Inj

    by AYUR

    4685.50per tablet
  • Etacept 25mg Injection 3ml

    by AYUR

    819.73per tablet
  • Rymti 25Mg/0.5Ml Inj

    4674.00per tablet
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