ENBREL 25MG INJECTION is an immunosuppressant medicine that helps reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, psoriatic arthritis, and plaque psoriasis. ENBREL 25MG INJECTION is generally used alone or in combination with methotrexate medicine.

ENBREL 25MG INJECTION consists of Etanercept, which belongs to the TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused due to various autoimmune diseases.

ENBREL 25MG INJECTION may cause certain side effects such as tingling or numbness, dizziness, shortness of breath, bleeding, pale skin, bruising, vision problem, redness on the skin and arms, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. ENBREL 25MG INJECTION is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. ENBREL 25MG INJECTION may cause dizziness, so drive only if you are alert and focused. ENBREL 25MG INJECTION should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of liver damage. ENBREL 25MG INJECTION is not recommended for use in pregnant and nursing mothers as it can cause serious adverse effects on the baby.

ENBREL 25MG INJECTION consists of Etanercept, which belongs to TNF (Tumor necrosis factor) inhibitor class of drugs. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and other autoimmune disorders.

• Tingling or numbness
• Dizziness
• Shortness of breath
• Bleeding
• Bruising
• Vision problem
• Redness on the skin and arms
• Injection site reactions

ENBREL 25MG INJECTION should be avoided if allergic to it or any other components present.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, Hepatitis B Virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), and diabetes as it can worsen your health condition. Do not take live vaccines while being treated with ENBREL 25MG INJECTION to prevent any serious consequences. ENBREL 25MG INJECTION may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with ENBREL 25MG INJECTION as it could lead to increased dizziness and risk of stomach bleeding/ulcers. ENBREL 25MG INJECTION is not recommended for use in children below two years of age as safety and efficacy is not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interaction: ENBREL 25MG INJECTION may interact with other immunosuppressants (certolizumab, golimumab, infliximab, adalimumab, rituximab), medicines used to treat rheumatoid arthritis (anakinra), blood thinners (warfarin), cholesterol-lowering drugs (atorvastatin, lovastatin, simvastatin), acidity treating medicines (omeprazole), cough suppressants (Dextromethorphan), live vaccines, Alkylating agents (cyclophosphamide) and birth control pills.

Drug-Food Interaction: Alcohol consumption may cause dizziness and increase bleeding risk and liver injury.

Drug-Disease Interaction: ENBREL 25MG INJECTION should be used with caution in liver or kidney disease cases, heart failure, multiple sclerosis, diabetes, weak immune system (HIV), hepatitis B, cancer, and serious infections.

• CERTOLIZUMAB
• INFLIXIMAB
• ADALIMUMAB
• ANAKINRA
• WARFARIN
• SIMVASTATIN
• OMEPRAZOLE
• DEXTROMETHORPHAN
• ATORVASTATIN
• CYCLOPHOSPHAMIDE

• Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Massages can also be helpful.
• Avoid freezing and hot temperatures.
• Avoid wearing tight-fitting clothes; instead, wear loose garments.
• Rest well and get plenty of sleep.
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
• Stay hydrated; drink plenty of water.

• It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment though the patient gets a negative tuberculin test.
• It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting ENBREL 25MG INJECTION.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that causes joint pain and damage. It occurs when the immune system does not work properly. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints, or other body parts. Ankylosing spondylitis symptoms include decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

Psoriatic arthritis: It is a type of inflammatory arthritis which occurs in patients with psoriasis. It could also occur in patients without psoriasis, particularly in those with a family history of psoriasis. It affects large joints in the lower extremities, the distal joints of toes and fingers, and the back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.