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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

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Whats That

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Composition :

DANAZOL-50MG

Manufacturer/Marketer :

Ar-Ex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Endometryl 50 Capsule

Endometryl 50 Capsule belongs to the class of drugs called synthetic steroids used to treat endometriosis and breast cysts. Endometriosis is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

Endometryl 50 Capsule contains Danazol which works by suppressing the activity of ovaries. Thus, it decreases the amount of estrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

Take Endometryl 50 Capsule as prescribed by your doctor. You are advised to take Endometryl 50 Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience sore throat, hoarse voice, hair loss, excessive hair growth on the body or face, stomach pain, skin rashes, or chest pain. Most of these side effects of Endometryl 50 Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Endometryl 50 Capsule or any other medicines, please tell your doctor. Endometryl 50 Capsule is contraindicated in pregnant and breastfeeding women. You are recommended to avoid or limit consumption of alcohol with Endometryl 50 Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Endometryl 50 Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Endometryl 50 Capsule as it may increase the effect of certain anesthetics.

Uses of Endometryl 50 Capsule

Endometriosis, Breast lumps

Directions for Use

Take Endometryl 50 Capsule with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Endometryl 50 Capsule contains Danazol which decreases the amount of estrogen in the body by suppressing the activity of ovaries. Thus, Endometryl 50 Capsule induces temporary menopause and shrinks the tissue outside the uterus or stops its growth. Also, Endometryl 50 Capsule works by inhibiting the release of hormones in the body that cause breast pain and lumps.

Storage

Store in a cool and dry place away from sunlight
Side effects of Endometryl 50 Capsule
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Drug Warnings

If you are allergic to Endometryl 50 Capsule or any other medicines, please tell your doctor. Endometryl 50 Capsule is contraindicated in pregnant and breastfeeding women. It is advised to use effective non-hormonal contraceptives to avoid pregnancy while taking Endometryl 50 Capsule as it may cause birth defects. You are recommended to avoid or limit consumption of alcohol with Endometryl 50 Capsule as it may cause shortness of breath or make you feel sick. Drive only if you are alert as Endometryl 50 Capsule may cause dizziness, vertigo (spinning feeling), or blurred vision. If you are about to undergo any surgery, please inform your doctor that you are taking Endometryl 50 Capsule as it may increase the effect of certain anesthetics. If you have pain while moving your legs or arms, stop taking Endometryl 50 Capsule and consult a doctor immediately as this might be due to a blood clot.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Endometryl 50 Capsule:
Combining Endometryl 50 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin.

How to manage the interaction:
Taking Endometryl 50 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Endometryl 50 Capsule:
Using pimozide together with Endometryl 50 Capsule may significantly increase the blood levels of pimozide.

How to manage the interaction:
Taking Endometryl 50 Capsule with Pimozide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medication without doctor's advice.
How does the drug interact with Endometryl 50 Capsule:
Co-administration of Vilazodone with Endometryl 50 Capsule can increase the blood levels of Vilazodone.

How to manage the interaction:
Taking Endometryl 50 Capsule with Vilazodone together can result in an interaction, but it can be taken if a doctor has advised it. If you experience any symptoms such as diarrhea, nausea, vomiting, dry mouth, dizziness, or sleep disturbances, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Endometryl 50 Capsule:
Using Lovastatin together with Endometryl 50 Capsule may significantly increase the blood levels of Lovastatin.

How to manage the interaction:
Although there is a possible interaction between Endometryl 50 Capsule and Lovastatin, you can take these medicines together if prescribed by your doctor. However, if you experience a muscle tenderness, muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes contact a doctor right away. Do not discontinue any medications without first consulting your doctor.
DanazolMipomersen
Severe
How does the drug interact with Endometryl 50 Capsule:
Combining Mipomersen with Endometryl 50 Capsule may increase the risk of liver problems.

How to manage the interaction:
Co-administration of Endometryl 50 Capsule with Mipomersen can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, bleeding, or liver damage contact a doctor right away. Do not stop using any medications without first talking to a doctor.
DanazolLomitapide
Severe
How does the drug interact with Endometryl 50 Capsule:
Combining Lomitapide with Endometryl 50 Capsule can increase the blood levels of Lomitapide.

How to manage the interaction:
Co-administration of Endometryl 50 Capsule with Lomitapide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience diarrhea, nausea, stomach pain, constipation, or any other discomfort, fever, joint pain, or skin rash consult a doctor. Do not stop using any medications without first talking to your doctor.
DanazolHalofantrine
Severe
How does the drug interact with Endometryl 50 Capsule:
Using Halofantrine together with Endometryl 50 Capsule may increase the blood levels of Halofantrine.

How to manage the interaction:
Although there is a possible interaction between Endometryl 50 Capsule and Halofantrine, you can take these medicines together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact a doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Endometryl 50 Capsule:
Using cisapride together with Endometryl 50 Capsule may significantly increase the blood levels of cisapride.

How to manage the interaction:
Although there is a possible interaction between Endometryl 50 Capsule and Cisapride, you can take these medicines together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, contact a doctor right away. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Endometryl 50 Capsule:
Using atorvastatin together with Endometryl 50 Capsule may significantly increase the blood levels of atorvastatin.

How to manage the interaction:
Concomitant administration of atorvastatin along with Endometryl 50 Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop taking any medication without doctor's advice.
How does the drug interact with Endometryl 50 Capsule:
Combining Leflunomide with Endometryl 50 Capsule may increase the risk of liver problems.

How to manage the interaction:
Co-administration of Endometryl 50 Capsule with Teriflunomide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or unusual bleeding contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

SYNTHETIC ANABOLIC STEROID

Endometryl 50 Capsule Substitute

Substitutes safety advice
  • Danogen-50 Capsule 10's

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  • Gonablok 50 Capsule 10's

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  • Zendol 50 mg Capsule 10's

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  • Gynazol 50 Capsule 10's

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  • Danzest 50mg Capsule

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    12.63per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Endometryl 50 Capsule contains Danazol that works by suppressing the activity of ovaries. Thus, it decreases the amount of oestrogen in the body and induces temporary menopause. Thereby, it shrinks the tissue outside the uterus or stops its growth.

You are not recommended to use a contraceptive pill with Endometryl 50 Capsule as it may decrease the effectiveness of hormonal contraceptives. Therefore, it is advised to use effective non-hormonal contraceptives such as Intra-Uterine Device or barrier method in conjunction with contraceptive jelly or foam. However, please consult a doctor if you have any concerns regarding this.

Endometryl 50 Capsule may be used to treat breast lumps when other treatments have not worked. Endometryl 50 Capsule inhibits the release of hormones in the body that cause breast pain and lumps.

Endometryl 50 Capsule may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking Endometryl 50 Capsule and inform your doctor if you have diabetes before taking Endometryl 50 Capsule .

You are not recommended to take Endometryl 50 Capsule with simvastatin as it may increase the levels of simvastatin in the blood and increase the risk of liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue). However, please consult a doctor before taking Endometryl 50 Capsule with other medicines.

Endometryl 50 Capsule is not recommended for patients suffering from severe liver disease as it may worsen the condition. Therefore, inform your doctor if you have any liver disease before taking Endometryl 50 Capsule .

Drug-Drug Interactions Checker List

  • WARFARIN
  • TACROLIMUS
  • CICLOSPORIN
  • SIMVASTATIN
  • ALFACALCIDOL
  • PROGESTERONE
  • TESTOSTERONE
  • ESTROGEN

Special Advise

  • If you are supposed to take Endometryl 50 Capsule for more than 6 months, your doctor may recommend an ultrasound test to check your liver condition.
  • Regular blood tests are recommended while taking Endometryl 50 Capsule to monitor liver functioning and blood levels.
  • Endometryl 50 Capsule may affect the results of certain blood tests used to check liver and thyroid function, hormone testosterone levels, sugars, fats, and protein levels in the blood. Therefore, inform your doctor that you are taking Endometryl 50 Capsule before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse or discomfort with bowel movements. 

Breast cysts (lumps): These lumps are non-cancerous but may be painful. Breast lumps may be caused due to milk cysts (sacs filled with milk) that may occur during breastfeeding, fibrocystic breasts (breast tissue feels lumpy), injury or mastitis (infection of breast).

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