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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

SILDENAFIL-25MG

Manufacturer/Marketer :

Karisca Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Endowal-S Tablet

Endowal-S Tablet belongs to the group of medicines called phosphodiesterase type-5 (PDE 5) inhibitors primarily used to treat erectile dysfunction (impotence) in adult men. Additionally, Endowal-S Tablet may also be used to treat pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening.
 
Endowal-S Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. Thus, Endowal-S Tablet helps treat erectile dysfunction. Endowal-S Tablet relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treating pulmonary hypertension.
 
You are advised to take Endowal-S Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Endowal-S Tablet may cause side effects such as headache, nausea, dizziness, indigestion and stomach upset. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not take Endowal-S Tablet if you are allergic to any of the components or if you are taking nitrate medicines or riociguat (a drug used to treat pulmonary hypertension). Endowal-S Tablet is not recommended for use in children. Consult your doctor if you experience hearing or visual impairment. Avoid consumption of alcohol as it may impair your ability to get an erection. Taking Endowal-S Tablet after a heavy meal might take longer time for the medicine to work; therefore you are advised to take Endowal-S Tablet with light meals.

Uses of Endowal-S Tablet

Erectile dysfunction (impotence), Pulmonary arterial hypertension

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water as a whole. Do not crush, break or chew the tablet. Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose using the measuring cup provided by the pack.Powder for oral suspension: Check the label for directions before use. Add the prescribed quantity of water to the powder, close the cap and shake vigorously for 30 seconds. Take the prescribed dose using the dosing syringe.Sachet: Open the sachet and consume the entire contents.Orally disintegrating strip: Keep the strip in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.Jelly: Place the jelly in the mouth or under the tongue and allow it to dissolve.Effervescent tablets: Check the label for directions and take it as advised by the doctor. Dissolve the effervescent tablet in half glass of water and consume the solution immediately.

Medicinal Benefits

Endowal-S Tablet belongs to the group of medicines called phosphodiesterase type-5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) in adult men and pulmonary arterial hypertension (high blood pressure in the lungs) in adults to improve the ability to exercise and to slow down clinical worsening. Endowal-S Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited. However, Endowal-S Tablet helps the person to get an erection only if he is sexually stimulated. Endowal-S Tablet relaxes the blood vessels, increases the blood supply to the lungs and reduces the workload of the heart. Thereby, treats pulmonary hypertension.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Endowal-S Tablet if you are allergic to any of the components, if you are taking medicines called nitrates which are used to treat angina or chest pain, or guanylate cyclase stimulator medicines (used to treat heart failure and PAH). Inform your doctor if you have/had heart problems such as angina, heart attack, irregular heartbeat, or heart failure, blood circulation problems, low blood pressure, eye or ear problems, sickle cell anaemia (an abnormality of red blood cells), multiple myeloma (cancer of bone marrow), leukaemia (cancer of blood cells), stomach ulcer, bleeding problems, problems with the shape of the penis or Peyronie's disease (a condition that causes painful erections).

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Endowal-S Tablet:
Coadministration of Indinavir and Endowal-S Tablet can increase the blood levels and side effects of Endowal-S Tablet.

How to manage the interaction:
Taking Indinavir and Endowal-S Tablet together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Endowal-S Tablet:
Coadministration of Isosorbide dinitrate and Endowal-S Tablet can increase the risk of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate and Endowal-S Tablet together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilTelaprevir
Critical
How does the drug interact with Endowal-S Tablet:
Combining Telaprevir and Endowal-S Tablet can increase the blood levels and effects of Endowal-S Tablet.

How to manage the interaction:
Taking Telaprevir and Endowal-S Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilSaquinavir
Critical
How does the drug interact with Endowal-S Tablet:
Coadministration of Saquinavir and Endowal-S Tablet can increase the blood levels and side effects of Endowal-S Tablet.

How to manage the interaction:
Taking Saquinavir and Endowal-S Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Endowal-S Tablet:
Coadministration of Ritonavir and Endowal-S Tablet may significantly increase the blood levels of Endowal-S Tablet.

How to manage the interaction:
Taking Endowal-S Tablet with Ritonavir together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Endowal-S Tablet:
Co-administration of Endowal-S Tablet with Riociguat may lower the blood pressure.

How to manage the interaction:
Taking Riociguat and Endowal-S Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SildenafilFosamprenavir
Critical
How does the drug interact with Endowal-S Tablet:
Coadministration of Fosamprenavir and Endowal-S Tablet can increase the blood levels and effects of Endowal-S Tablet.

How to manage the interaction:
Taking Fosamprenavir and Endowal-S Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Endowal-S Tablet:
Combining Darunavir and Endowal-S Tablet can increase the blood levels and effects of Endowal-S Tablet.

How to manage the interaction:
Taking Darunavir and Endowal-S Tablet together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilAmprenavir
Critical
How does the drug interact with Endowal-S Tablet:
Coadministration of Amprenavir and Endowal-S Tablet can increase the blood levels and effects of Endowal-S Tablet.

How to manage the interaction:
Taking Amprenavir and Endowal-S Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SildenafilNitroprusside
Critical
How does the drug interact with Endowal-S Tablet:
Coadministration of Endowal-S Tablet with Nitroprusside can increase the risk of developing low blood pressure.

How to manage the interaction:
Taking Endowal-S Tablet with Nitroprusside together is generally avoided as it can lead to an interaction, it can be taken only if prescribed by your doctor. If you experience any side effects such as dizziness, lightheadedness, headache, or heart palpitations you should seek immediate medical attention. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintaining a healthy weight, eating balanced diet and regular exercising may help you manage erectile dysfunction.
  • Avoid consumption of alcohol as it may temporarily impair your ability to get an erection.
  • Avoid usage of tobacco.
  • Share intimate time with your partner.

Habit Forming

No

Therapeutic Class

PDE5-INHIBITORS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Endowal-S Tablet works by relaxing the blood vessels in the penis, thereby allowing the blood to flow into the penis when the person is sexually excited.

No, do not take Endowal-S Tablet with nitrates. Taking Endowal-S Tablet with medicines used to treat angina/chest pain such as nitrates/nitroglycerin may cause severe lowering of blood pressure. Consult your doctor if you have a history of heart attack/stroke.

Caution is advised if Endowal-S Tablet is taken with alpha-blockers or blood-pressure-lowering medicines. Endowal-S Tablet relaxes and widens the blood vessels; this causes a decrease in blood pressure. Therefore, if Endowal-S Tablet is taken along with blood-pressure-lowering medicines it might cause further lowering in blood pressure. Consult your doctor if you are taking alpha-blockers or anti-hypertensives.

In some cases, Endowal-S Tablet may cause sudden vision loss in one or both eyes. Stop taking Endowal-S Tablet and consult your doctor immediately if you experience a sudden decrease or loss of vision.

Endowal-S Tablet may cause low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Drug-Drug Interactions Checker List

  • NITROGLYCERIN
  • RIOCIGUAT
  • RITONAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE

Special Advise

  • Do not take Endowal-S Tablet more than once in a day if prescribed for erectile dysfunction. 
  • Talk to your doctor if the erection persists for greater than four hours after the sexual intercourse.

Disease/Condition Glossary

Erectile dysfunction: It is the inability to keep a hard and erect penis suitable for sexual intercourse. It could be a sign of physical or psychological conditions such as fear of sexual failure, anxiety, depression, low self-esteem, or stress. Certain health-related factors such as smoking, drinking, being overweight, being physically inactive, and high blood pressure also contribute to erectile dysfunction. Symptoms of erectile dysfunction include difficulty in getting an erection, difficulty in maintaining the erection during intercourse and decreased sexual desire. 

Pulmonary arterial hypertension (PAH): High blood pressure affects the arteries in the lungs and heart, leading to pulmonary arterial hypertension. It occurs due to narrowed or blocked blood vessels which increases the workload on the heart. Symptoms include chest pain, dizziness, fatigue, and swelling in the legs and ankles.

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