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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About ENZOFLEX 4MG TABLET

ENZOFLEX 4MG TABLET is a combination medication primarily used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, torticollis (neck muscle contractions), and upper and lower back pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

ENZOFLEX 4MG TABLET is a combination of two drugs: Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of ENZOFLEX 4MG TABLET include nausea, vomiting, loss of appetite, stomach pain, diarrhoea, and heartburn. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting ENZOFLEX 4MG TABLET, inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. ENZOFLEX 4MG TABLET is not recommended for pregnant and breastfeeding women. ENZOFLEX 4MG TABLET should not be given to children and adolescents below 18 years of age as safety has not been established. Avoid consuming alcohol while undergoing treatment with ENZOFLEX 4MG TABLET. 

Uses of ENZOFLEX 4MG TABLET

Pain due to muscle spasms.

Directions for Use

Swallow it as a whole with a glass of water. Do not chew, crush or break it.

Medicinal Benefits

ENZOFLEX 4MG TABLET treats pain due to muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAIDs) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevents the formation of chemical messengers called 'prostaglandins (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This helps reduce muscle stiffness and improves muscle movements, thereby relieving pain due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ENZOFLEX 4MG TABLET

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Heartburn

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), autoimmune diseases (systemic lupus erythematosus), and smoking habit. Please consult your doctor before starting ENZOFLEX 4MG TABLET if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with ENZOFLEX 4MG TABLET unless prescribed. Stop taking ENZOFLEX 4MG TABLET and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. ENZOFLEX 4MG TABLET is not recommended for pregnant and breastfeeding women. ENZOFLEX 4MG TABLET may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol while being treated with ENZOFLEX 4MG TABLET. This medicine is not recommended in children and adolescents below 18 years of age as safety and efficacy are not established.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacDasatinib
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Enzoflex 4mg Tablet:
Co-administration of Enzoflex 4mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Enzoflex 4mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacDasatinib
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking Dasatinib together with Enzoflex 4mg Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflex 4mg Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacHuman immunoglobulin
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking Enzoflex 4mg Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Enzoflex 4mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacCelecoxib
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Co-administration of Enzoflex 4mg Tablet with Celecoxib may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although there is a interaction between Enzoflex 4mg Tablet and Celecoxib, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacRamucirumab
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Co-administration of Enzoflex 4mg Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflex 4mg Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacOmacetaxine mepesuccinate
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking Enzoflex 4mg Tablet with Omacetaxine mepesuccinate can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Enzoflex 4mg Tablet and Omacetaxine mepesuccinate but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacLeflunomide
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Co administration of Enzoflex 4mg Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Enzoflex 4mg Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacAcalabrutinib
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking acalabrutinib together with Enzoflex 4mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Enzoflex 4mg Tablet and Acalabrutinib can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking Enzoflex 4mg Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflex 4mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacAmiloride
Severe
How does the drug interact with Enzoflex 4mg Tablet:
Taking amiloride with Enzoflex 4mg Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Enzoflex 4mg Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS

ENZOFLEX 4MG TABLET Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ENZOFLEX 4MG TABLET contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that relieves muscle stiffness due to muscle spasms and improves muscle movements.

ENZOFLEX 4MG TABLET is usually prescribed for a short period and can be discontinued if there is no pain. To treat your condition effectually, continue taking ENZOFLEX 4MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ENZOFLEX 4MG TABLET.

Diarrhoea can be a side-effect of ENZOFLEX 4MG TABLET. Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

It is not advised to use other NSAIDs or pain killers while using ENZOFLEX 4MG TABLET. Please seek medical advice for further information.

You are not recommended to take ENZOFLEX 4MG TABLET with warfarin as simultaneous use of these two medicines may increase the bleeding risk. However, if you are supposed to use these medicines together, please contact your doctor so that the dose may be adjusted or you may be prescribed alternate medicine.

Drug-Drug Interactions Checker List

  • WARFARIN
  • LITHIUM
  • METHOTREXATE
  • CICLOSPORIN
  • TACROLIMUS
  • TRIMETHOPRIM
  • MIFEPRESTONE
  • ASPIRIN
  • IBUPROFEN
  • DIGOXIN
  • VORICONAZOLE
  • PHENYTOIN
  • COLESTIPOL
  • CHOLESTYRAMINE

Special Advise

  • Let your doctor know that you are taking ENZOFLEX 4MG TABLET if you are undergoing any medical tests.
  • Your doctor may recommend liver function tests to monitor your liver functioning.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. At the same time, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.

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