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  1. Home
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  3. EPALPEX 150MG SR TABLET

EPALPEX 150MG SR TABLET, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

EPALRESTAT-150MG

Manufacturer/Marketer :

Shilpex Pharmysis

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About EPALPEX 150MG SR TABLET

EPALPEX 150MG SR TABLET belongs to a group of medicines called aldose reductase inhibitors used to manage diabetic neuropathy. Diabetic neuropathy is a chronic progressive nerve disease which causes nerve pain due to nerve damage in diabetic patients. It mostly affects the legs and feet.

EPALPEX 150MG SR TABLET contains ‘Epalrestat’ that works by inhibiting aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. EPALPEX 150MG SR TABLET prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

You are advised to take EPALPEX 150MG SR TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking EPALPEX 150MG SR TABLET if you are pregnant or breastfeeding. EPALPEX 150MG SR TABLET may cause drowsiness and dizziness, so drive only if you are alert. EPALPEX 150MG SR TABLET is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with EPALPEX 150MG SR TABLET as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of EPALPEX 150MG SR TABLET

Diabetic neuropathy (diabetic nerve pain)

Directions for Use

Swallow EPALPEX 150MG SR TABLET as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

EPALPEX 150MG SR TABLET belongs to a group of medicines called aldose reductase inhibitors. EPALPEX 150MG SR TABLET is used for the management of diabetic neuropathy. EPALPEX 150MG SR TABLET works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients who have diabetes which leads to nerve pain. EPALPEX 150MG SR TABLET prevents sorbitol accumulation, thereby treating diabetic neuropathy (pain due to nerve damage).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take EPALPEX 150MG SR TABLET if you are allergic to any of its contents. Inform your doctor if you have liver or kidney problems. Consult your doctor before taking EPALPEX 150MG SR TABLET if you are pregnant or breastfeeding. EPALPEX 150MG SR TABLET may cause drowsiness and dizziness, so drive only if you are alert. EPALPEX 150MG SR TABLET is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with EPALPEX 150MG SR TABLET as it could lead to increased drowsiness and sleepiness.

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

EPALPEX 150MG SR TABLET Substitute

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

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FAQs

EPALPEX 150MG SR TABLET works by inhibiting aldose reductase enzyme which catalyses the conversion of glucose to sorbitol. EPALPEX 150MG SR TABLET prevents the accumulation of sorbitol, thereby helps in treating diabetic neuropathy.

Diarrhoea could be a side-effect of EPALPEX 150MG SR TABLET. Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.

EPALPEX 150MG SR TABLET might cause high blood pressure. So, if you have hypertension, consult your doctor before taking EPALPEX 150MG SR TABLET. Regularly monitor blood pressure levels while taking EPALPEX 150MG SR TABLET.

Do not discontinue EPALPEX 150MG SR TABLET without consulting your doctor. To treat your condition effectually, continue taking EPALPEX 150MG SR TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking EPALPEX 150MG SR TABLET.

EPALPEX 150MG SR TABLET may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. If you have diabetes and experience numbness, pain, tingling sensation, or weakness in the hands or legs, you must consult a doctor. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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